RHT constitutive model parameters for rock [34]. by Hai Rong (18422937)

“…When the lateral stress coefficient and joint angle are the same, an increase in initial in-situ stress results in a reduction in the area of the blasting damage zone. (2) Under the same initial in-situ stress conditions, the area of the blasting damage zone initially increases and then decreases with an increasing joint angle. …”

Actin oscillations depend on the extent and timing of Gβ sequestration. by Oliver Hoeller (2148580)

“…To achieve stable, intermediate levels of Gβ sequestration, cells were cotreated with 300 nM rapamycin and 0, 5, 10, 20 or 40 μM FK506, a competitive inhibitor of rapamycin. …”

Image 1_Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage.jpeg by Peter Linde (22011383)

“…STING-MSC-CM decreased IL-6, IL-8 secretion (p = 0.08) by synoviocytes, decreased IL-8 (p = 0.05) by activated chondrocytes, increased G-CSF (p = 0.01), IL-4 (p = 0.01) and decreased IL-5 (p = 0.01) by activated macrophages. …”

Table1.DOCX by Kemin Yan (4924420)

“…The total WAT mass of the IT rats showed a 41.5% reduction compared with the Sham-IT rats, and serum levels of FGF21 and leptin of the IT rats decreased by 26.3 and 61.7%, respectively (all P < 0.05). …”

Table2.DOCX by Kemin Yan (4924420)

“…The total WAT mass of the IT rats showed a 41.5% reduction compared with the Sham-IT rats, and serum levels of FGF21 and leptin of the IT rats decreased by 26.3 and 61.7%, respectively (all P < 0.05). …”

Computational modeling of the bimodal distribution of RPs and altered parameters of the resting ion channels on the distribution of RPs. by Yuqin Yang (579353)

“…We computed the instantaneous conductances of Kir and K_D by Boltzmann equations, and the membrane potentials by the Hodgkin-Horowitz equation: <math><mrow><msub><mi>G</mi><mrow><mi>K</mi><mi>i</mi><mi>r</mi></mrow></msub><mo>=</mo><msub><mi>G</mi><mrow>max<mo>,</mo><mi>K</mi><mi>i</mi><mi>r</mi></mrow></msub><mo>/</mo><mrow><mo>(</mo><mrow><mn>1</mn><mo>+</mo>exp<mrow><mo>(</mo><mrow><mrow><mo>(</mo><mrow><msub><mi>V</mi><mi>m</mi></msub><mo>−</mo><msub><mi>V</mi><mrow><mn>0.5</mn></mrow></msub></mrow><mo>)</mo></mrow><mo>/</mo><mi>k</mi></mrow><mo>)</mo></mrow></mrow><mo>)</mo></mrow></mrow></math>; <math><mrow><msub><mi>G</mi><mrow><mi>K</mi><mi>D</mi></mrow></msub><mo>=</mo><msub><mi>G</mi><mrow>max<mo>,</mo><mi>K</mi><mi>D</mi></mrow></msub><mo>−</mo><msub><mi>G</mi><mrow>max<mo>,</mo><mi>K</mi><mi>D</mi></mrow></msub><mo>/</mo><mrow><mo>(</mo><mrow><mn>1</mn><mo>+</mo>exp<mrow><mo>(</mo><mrow><mrow><mo>(</mo><mrow><msub><mi>V</mi><mi>m</mi></msub><mo>−</mo><msub><mi>V</mi><mrow><mn>0.5</mn></mrow></msub></mrow><mo>)</mo></mrow><mo>/</mo><mi>k</mi></mrow><mo>)</mo></mrow></mrow><mo>)</mo></mrow></mrow></math>; <math><mrow><msub><mi>V</mi>m</msub><mo>=</mo><mrow><mo>(</mo><mrow><msub><mi>E</mi><mi>K</mi></msub><mo>*</mo><mrow><mo>(</mo><mrow><msub><mi>G</mi><mrow><mi>K</mi><mi>i</mi><mi>r</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mrow><mi>K</mi><mi>N</mi><mi>V</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mrow><mi>K</mi><mi>D</mi></mrow></msub></mrow><mo>)</mo></mrow><mo>+</mo><msub><mi>E</mi><mi>L</mi></msub><mo>*</mo><msub><mi>G</mi><mi>L</mi></msub></mrow><mo>)</mo></mrow><mo>/</mo><mrow><mo>(</mo><mrow><msub><mi>G</mi><mrow><mi>K</mi><mi>i</mi><mi>r</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mrow><mi>K</mi><mi>N</mi><mi>V</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mrow><mi>K</mi><mi>D</mi></mrow></msub><mo>+</mo><msub><mi>G</mi><mi>L</mi></msub></mrow><mo>)</mo></mrow></mrow></math>; Stable RPs were determined by programmed computation with MatLab software using up to 200 iterations after the initial parameters input (See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125266#pone.0125266.s001" target="_blank">S1 Dataset</a> for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125266#pone.0125266.g008" target="_blank">Fig 8<b><i>A—</i></b> 8<b><i>I</i></b></a>). …”

Data_Sheet_1_Stroke care during the COVID-19 pandemic: Case numbers, treatments, and mortality in two large German stroke registries.PDF by Alicia Brunssen (13136349)

“…</p>Results<p>Hospitalization numbers decreased in the two stroke registries by 8% and 10% in Q2 of 2020 and by 5% and 15% in Q4 of 2020 compared to the same quarters in 2019, respectively. …”

AKT2 regulated the tumorigenic potential of neuroblastoma cells <i>in vitro</i>. by Jingbo Qiao (382330)

“…<p>(<b>A</b>) AKT2 expression was measured in BE(2)-C/shCON and BE(2)-C/shAKT2 cells by Western blotting and consistent knockdown of AKT2 was confirmed. …”

Data_Sheet_1_Extreme Low-Temperature Stress Affects Nutritional Quality of Amino Acids in Rice.docx by Min Kang (287002)

“…<p>Global climate change has increased the frequency of extreme climate events, and their effects on the nutritional quality, especially on amino acids in rice, have not been quantified. The data from a 3-year low temperature stress (LTS) experiment including two rice varieties (Huaidao 5 and Nanjing 46), seven minimum/maximum temperature levels (one optimal 21/27°C and six LTS levels from 17/23 to 6/12°C), and three LTS durations (3, 6, and 9 days) after flowering, revealed significant interactive effects of LTS at different stages, durations, and temperature levels on the content and accumulation of amino acids. …”

DataSheet_2_Cold Exposure Induces Depot-Specific Alterations in Fatty Acid Composition and Transcriptional Profile in Adipose Tissues of Pigs.docx by Yanbing Zhou (3442439)

“…In this study, we kept finishing pigs (lack a functional UCP1 gene) under cold (5-7°C) or room temperature (22-25°C) and determined the effects of overnight cold exposure on fatty acid composition and transcriptional profiles of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT). …”

Data_Sheet_1_Light Intensity Modulates the Effect of Phosphate Limitation on Carbohydrates, Amino Acids, and Catechins in Tea Plants (Camellia sinensis L.).pdf by Santosh KC (1650817)

“…The results from young shoots showed that amino acids, pentose phosphate, and flavonol glycosides pathways were enhanced in response to decreasing light intensities and P deficiency. The expression of the genes hexokinase 1, ribose 5-phosphate isomerase A (RPIA), glutamate synthetase 1 (GS1), prolyl 4-hydroxylase (P4H), and arginase was induced by P limitation, thereafter affecting carbohydrates and amino acids metabolism, where shading modulated the responses of transcripts and corresponding metabolites caused by P deficiency. …”

Data_Sheet_2_Light Intensity Modulates the Effect of Phosphate Limitation on Carbohydrates, Amino Acids, and Catechins in Tea Plants (Camellia sinensis L.).pdf by Santosh KC (1650817)

“…The results from young shoots showed that amino acids, pentose phosphate, and flavonol glycosides pathways were enhanced in response to decreasing light intensities and P deficiency. The expression of the genes hexokinase 1, ribose 5-phosphate isomerase A (RPIA), glutamate synthetase 1 (GS1), prolyl 4-hydroxylase (P4H), and arginase was induced by P limitation, thereafter affecting carbohydrates and amino acids metabolism, where shading modulated the responses of transcripts and corresponding metabolites caused by P deficiency. …”

Effects of 15-LOX-1 gene transfer on retinal levels of PPAR-γ and VEGFR-2. by Zhi Li (72309)

“…OIR-LOX-GFP group versus OIR group *p<0.05; #p<0.05, OIR-LOX-GFP group versus OIR-GFP group **p<0.05; ##p<0.05, n = 5. C: Real-time PCR analysis of PPAR-γ and VEGFR-2 expression further showed that mRNA levels of PPAR-γ were significantly increased in OIR-LOX-GFP group and Control group, and decreased in OIR group and OIR-GFP group, whereas mRNA levels of VEGFR-2 were significantly increased in OIR group and OIR-GFP group, and decreased in OIR-LOX-GFP group and Control group. …”

Tumor suppressor function of <i>RBMS3</i> in NPC cells. by Juan Chen (61123)

“…<p>Expression of <i>RBMS3</i> in <i>RBMS3</i>-transfected SUNE1 (SUNE1-R4 and R5) and CNE2 cells (CNE2-R1 and R2) was confirmed by quantitative PCR (<b>A</b>) and Western blot (<b>B</b>). …”

Data Sheet 1_Cardiac T1 mapping in non-ST-segment elevation myocardial infarction: temporal changes in myocardial fibrosis.pdf by Luis Paiva (7175234)

“…Myocardial fibrosis assessed using LGE showed a decreasing trend at follow-up (9.4 ± 4.4% vs. 6.7 ± 4.4%; p = 0.051), particularly in the MI culprit coronary artery regions (14.2 ± 8.6% vs. 9.5 ± 7.0%; p = 0.015). …”

The BMP and FGF pathways reciprocally regulate odontoblast differentiation by Karo Parsegian (13028274)

“…</p> <p>BMP2 activated SMAD1/5/8 but not ERK1/2 signaling, whereas FGF2 exerted opposite effects. …”

GSTA3 Attenuates Renal Interstitial Fibrosis by Inhibiting TGF-Beta-Induced Tubular Epithelial-Mesenchymal Transition and Fibronectin Expression - Fig 1 by Yun Xiao (14988)

“…<p><b>A) Renals of UUO rats underwent display significant pathological changes and an increase in collagen I expression</b>. …”

DataSheet_1_Cold Exposure Induces Depot-Specific Alterations in Fatty Acid Composition and Transcriptional Profile in Adipose Tissues of Pigs.docx by Yanbing Zhou (3442439)

“…In this study, we kept finishing pigs (lack a functional UCP1 gene) under cold (5-7°C) or room temperature (22-25°C) and determined the effects of overnight cold exposure on fatty acid composition and transcriptional profiles of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT). …”

Experimental and Numerical Investigations of Soot Formation in the Laminar to Turbulent Transition of an Acetylene Diffusion Flame by Shijun Chen (835302)

Table_1_Age-Dependent Changes in Transcription Factor FOXO Targeting in Female Drosophila.XLSX by Allison Birnbaum (6669461)

“…Although the transcriptional regulation of FOXO have been previously characterized (especially in long-lived insulin mutants and under stress conditions), how normal aging impacts the transcriptional activity of FOXO is poorly understood. Here, we conducted a chromatin immunoprecipitation sequencing (ChIP-Seq) analysis in both young (2-week-old) and aged (5-week-old) wild-type female fruit flies, Drosophila melanogaster, to evaluate the dynamics of FOXO gene targeting during aging. …”