DataSheet_1_Terminal fucosylation of haptoglobin in cancer-derived exosomes during cholangiocarcinoma progression.pdf by Hyewon Choi (687527)

“…Mechanically, it is primarily due to β-haptoglobin (β-Hp) originating from CCA expressing fucosyltransferase-3/4 (FUT 3/4) and N-acetylglucosaminyltransferase-V (MGAT5). Newly synthesized β-Hp is loaded into EVs in early endosomes via a KFERQ-like motif and then secreted from CCA cells to induce tumor progression. …”

Data_Sheet_1_Sperm DNA Hypomethylation Proximal to Reproduction Pathway Genes in Maturing Elite Norwegian Red Bulls.DOCX by Abdolrahman Khezri (8055263)

“…Most of the identified DMRs (69%) exhibited a less than 10% methylation difference while only 1.5% of DMRs exceeded a 25% methylation difference. …”

Data Sheet 1_Unveiling causal immune cell–gene associations in multiple myeloma: insights from systematic reviews and Mendelian randomization analyses.docx by Hui Zhang (7197)

“…Post-adjustment for multiple testing, the levels of seven types of immune cells (two types of Treg, two types of TNBK, two types of B cells, and one type of Myeloid cell) were found to be elevated in association with an increased risk of multiple myeloma (MM), while the levels of another eight types of immune cells (one types of Treg, three types of TNBK, one type of MT cells, and two types of Myeloid cell and one type of cDC cells) were demonstrated to be associated with a decreased risk of MM. As supported by sensitivity analysis. …”

DataSheet1_QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.pd... by Gulinigaer Anwaier (6903299)

“…QSYQ also inhibited the following: release of RP S19 from the injured myocardium, activation of C5a receptors in monocytes, polarization of macrophages, and release of TGF-β1. …”

DataSheet1_Enhanced Antifungal and Wound Healing Efficacy of Statistically Optimized, Physicochemically Evaluated Econazole-Triamcinolone Loaded Silica Nanoparticles.docx by Safirah Maheen (10327003)

“…The stability of optimized drugs loaded MSNs prepared with 100 gm of oil at pH 5.6 with a stirring time of 2 h was confirmed from a zeta potential value of −25 mV. …”

Lack of LeuB results in increased proteolytic activity during iron starvation caused by leucine shortage. by Nanbiao Long (5900231)

“…(G) Northern blot analyses demonstrating that lack of LeuB significantly decreases <i>leuA</i> transcript levels during iron starvation but not iron sufficiency. …”

FluidFM-mediated injections of liquids and bacteria into enteroid-derived IECs. by Chantal Ernst (9953921)

“…Focused ion beam image of a FluidFM tip: Scale bar: 5 μm. (<b>B</b>) Dye injection into single IECs. …”

Expression of <i>SHH</i> in the FEZ after RCAS-virus infection to induce overexpression and knockdown of <i>PBX1</i> and <i>PBX3.</i> by Chan Hee Mok (11247669)

“…In the FNP (including the mesenchyme and the ectoderm), RCAS-mir<i>PBX1</i> (n = 6) decreased <i>PBX1</i> expression compared to the normal control (n = 6; <b>L</b>), and RCAS-mir<i>PBX3</i> (n = 6) decreased <i>PBX3</i> expression compared to the normal control (n = 4; <b>M</b>). …”

Table_1_Comprehensive Multi-Omics Identification of Interferon-γ Response Characteristics Reveals That RBCK1 Regulates the Immunosuppressive Microenvironment of Renal Cell Carcinom... by Wenhao Xu (2302681)

“…After RBCK1 expression was confirmed in ccRCC, we found a significantly decreased number of infiltrating CD4⁺ T cells, CD4⁺ FOXP3⁺ Treg cells, M1 macrophages, and CD56^bight/dim NK cells in the immune-cold RBCK1^high group. …”

Regorafenib sensitizes human breast cancer cells to radiation by inhibiting multiple kinases and inducing DNA damage by Meghna Mehta (8446044)

“…</p> <p>Regorafenib reduced cell proliferation and enhanced radiosensitivity of MDA-MB-231 and SUM159PT cell lines but had no effect on the MCF 10a cells. Clonogenic survival assays showed that the surviving fraction at 2 Gy for both MDA-MB-231 and SUM159PT was reduced from 66.4 ± 8.9 and 88.2 ± 1.7 in controls to 38.1 ± 4.9 and 75.1 ± 1.1 following a 24 hr pretreatment with 10 μM and 5 μM Regorafenib, respectively. …”

Dynamics of conceptual distance <i>d</i> and the growth effects of the data set by Artem Chumachenko (21681455)

“…</p> <p>The analysis of conceptual distance dynamics highlights that the expansion of the dataset, as reflected in the dynamics of <i>N</i> or <i>N</i>₀₀ in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0327793#pone.0327793.s003" target="_blank">S2 Fig</a>, does not affect the behavior of the distance <i>d</i> in the manner predicted by the model in Eq (5) when only the number of background documents of type <i>N</i> ₀₀ increases. …”

DataSheet_1_Segmentation stability of human head and neck cancer medical images for radiotherapy applications under de-identification conditions: Benchmarking data sharing and arti... by Jaakko Sahlsten (13165413)

“…Eight publicly available defacing algorithms were investigated: afni_refacer, DeepDefacer, defacer, fsl_deface, mask_face, mri_deface, pydeface, and quickshear. Using a subset of scans where defacing succeeded (N=29), a 5-fold cross-validation 3D U-net based OAR auto-segmentation model was utilized to perform two main experiments: 1.) comparing original and defaced data for training when evaluated on original data; 2.) using original data for training and comparing the model evaluation on original and defaced data. …”

Interactive “Video Doctor” Counseling Reduces Drug and Sexual Risk Behaviors among HIV-Positive Patients in Diverse Outpatient Settings by Paul Gilbert (90408)

“…</p><h3>Methodology and Findings</h3><p>We conducted a parallel groups randomized controlled trial (December 2003–September 2006) at 5 San Francisco area outpatient HIV clinics. …”

ICS-209-PLUS - An all-hazards dataset mined from the US National Incident Management System 1999-2014 by Lise St. Denis (6634934)

“…This system captures detailed information on incident management costs, personnel, hazard characteristics, values at risk, fatalities, and structural damage. Most (98.5%) of the reports are fire-related, followed in decreasing order by <i>other</i>, hurricane, hazardous materials, flood, tornado, search and rescue, civil unrest, and winter storms. …”

Effect of schistosomiasis on the outcome of patients infected with HIV-1 starting antiretroviral therapy in rural Tanzania by Katarina Stete (213207)

“…After adjustment for age, sex, body mass index, educational attainment, WHO-stage, tuberculosis status, and year of ART initiation, CAA-positivity showed a trend of a decreased hazard of death/LFU (HR: 0.58, 95% CI: 0.32–1.05, p = 0.07), while CD4 count at baseline (HR: 0.86, 95% CI: 0.76–1.00, p = 0.02) and MXD (sum of eosinophils, basophils, and monocytes counts) >1,100 cells/μl (HR: 0.56, 95% CI: 0.34–0.93, p = 0.03) were identified as independently protective factors.…”

Table_1_Application of starch degrading bacteria from tobacco leaves in improving the flavor of flue-cured tobacco.pdf by Yinuo Gong (16454715)

“…After treating flue-cured tobacco with an enzyme preparation prepared by the fermentation of Paenibacillus amylolyticus A17 #, the content of starch, pectin, and cellulose in flue-cured tobacco decreased significantly compared with the control group. …”

Table_1_An Endurance-Dominated Exercise Program Improves Maximum Oxygen Consumption, Ground Reaction Forces, and Muscle Activities in Patients With Moderate Diabetic Neuropathy.DOC... by AmirAli Jafarnezhadgero (5832632)

“…The progressive intervention program lasted 12 weeks with three sessions per week, each 40–55 min. …”

Effects of activated vitamin D, alfacalcidol, and low-intensity aerobic exercise on osteopenia and muscle atrophy in type 2 diabetes mellitus model rats by Manabu Akagawa (5866520)

“…After 6 weeks of treatment, ALF and Comb treatments decreased <i>Atrogin-1</i> and <i>REDD1</i>. These results demonstrate that a combination of ALF and Exe improved CSA from the early phase of treatment by stimulating skeletal muscle differentiation and suppressing muscle catabolic genes. …”

Effects of the MB and its derivatives on extracellular acidification rate (ECAR). by Ethan Poteet (125162)

“…The initial 35 minutes establishes a baseline reading, followed by addition of drug at a concentration of 10 µM. …”

Alkenyl/Thiol Co-Functionalized Titanium-Oxo Nanoclusters Enable Synergistic Lithography for Enhanced Resolution and Sensitivity by Zuohu Zhou (14258773)