AlgiMatrix™ Based 3D Cell Culture System as an In-Vitro Tumor Model for Anticancer Studies by Chandraiah Godugu (101721)

“…The cleaved caspase-3 expression was significantly decreased (2.09 and 2.47 folds respectively for 5-Fluorouracil and Camptothecin) in H460 spheroid cultures compared to 2D culture system. …”

Table_1_CD4 T Follicular Helper Cells Prevent Depletion of Follicular B Cells in Response to Cecal Ligation and Puncture.pdf by Matthew D. Taylor (8103320)

“…However, this reduction was less pronounced in immune educated mice than in controls and the percentage of CD4 T cells expressing a Tfh phenotype increased in the animals. CLP did not alter splenic architecture and decreased numbers of follicular, marginal, and germinal center B cells. …”

Image_3_CD4 T Follicular Helper Cells Prevent Depletion of Follicular B Cells in Response to Cecal Ligation and Puncture.TIFF by Matthew D. Taylor (8103320)

“…However, this reduction was less pronounced in immune educated mice than in controls and the percentage of CD4 T cells expressing a Tfh phenotype increased in the animals. CLP did not alter splenic architecture and decreased numbers of follicular, marginal, and germinal center B cells. …”

Extreme Wildlife Declines and Concurrent Increase in Livestock Numbers in Kenya: What Are the Causes? by Joseph O. Ogutu (785855)

“…As a result, livestock biomass was 8.1 times greater than that of wildlife in 2011–2013 compared to 3.5 times in 1977–1980. …”

Image2_The therapeutic targets and signaling mechanisms of ondansetron in the treatment of critical illness in the ICU.JPEG by Lili Tao (547628)

“…Background<p>There is accumulating evidence regarding the benefits of the 5-HT₃ receptor antagonist ondansetron for the treatment of critical illness due to its potential anti-inflammatory effect. …”

Data Sheet 1_Restoration of declining soil carbon stocks and lost surface elevations in degraded mangroves on the northern coast of Java, Indonesia.pdf by Trialaksita Sari Priska Ardhani (18053737)

“…Meanwhile, abandonment of ponds resulted in a loss of 34.24 Mg C ha^-1 in Wedung but a gain of 8.81 Mg C ha^-1 in Sayung. …”

Table_1_Distribution, Diversity, and Abundance of Nitrite Oxidizing Bacteria in the Subterranean Estuary of the Daya Bay.docx by Wei Sun (93580)

“…However, our understanding of Nitrospira distribution and their response to dynamic environmental parameters is still limited in the subterranean estuary (STE), a special environment of the mixed zone between land and sea. …”

Hydroxyurea alters hematological, biochemical and inflammatory biomarkers in Brazilian children with SCA: Investigating associations with βS haplotype and α-thalassemia by Sètondji Cocou Modeste Alexandre Yahouédéhou (6954542)

“…Those with the Benin haplotype presented increases in HbF and albumin levels, and a reduction in platelet counts (<i>p</i><0.05). …”

Coupled <i>in vitro</i> transcription/3′ end processing. by Sandra Holbein (336762)

“…Decreasing amounts of CF IA associated with ProtA-Clp1 or ProtA-Clp1 K136A T137A were analyzed for the presence of the four CF IA subunits Rna15, Pcf11, Clp1 and Rna14 as indicated on the right. …”

Graphical summary describing the signaling pathways potentially involved in Emo effects in nematodes. by Jürgen Krücken (225269)

“…DAG, diacyl glycerol; Emo, Emodepside; GABA_A-R, γ-aminobutyric acid A receptor; GPCR, G protein–coupled receptor; hGp, heterotrimeric G protein; IP3, inositol 1,4,5-trisphosphate; LAT-1, latrophilin-1; NO, nitric oxide; PIP2, phosphatidylinositol 4,5-bisphosphate; PKC-β, protein kinase C β; PLC, phospholipase C; SLO-1, slowpoke big K⁺ conductance channel.…”

Table2_Pan-cancer analysis identifies proteasome 26S subunit, ATPase (PSMC) family genes, and related signatures associated with prognosis, immune profile, and therapeutic response... by Hui Jia (638620)

“…Notably, they all shared a positive association with increased TMB, TIDE score, expression of immune checkpoints (CD276 and PVR), and more M1 macrophages but decreased B-cell abundance. …”

Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary... by Martina Korfei (2202892)

“…In agreement, both drugs decreased protein level of phosphorylated (p)-STAT3, a transcription factor mediating profibrotic responses, in treated IPF-fibroblasts. …”

Table1_Pan-cancer analysis identifies proteasome 26S subunit, ATPase (PSMC) family genes, and related signatures associated with prognosis, immune profile, and therapeutic response... by Hui Jia (638620)

“…Notably, they all shared a positive association with increased TMB, TIDE score, expression of immune checkpoints (CD276 and PVR), and more M1 macrophages but decreased B-cell abundance. …”

Norbornyl Cations of Group 14 Elements by Thomas Müller (3554)

“…This points to a reduced electrophilicity of the plumbacation compared to its predecessors.…”

Evaluation of PCR amplification bias and PCR amplification efficiency. by Trang Thi Quynh Tran (20485595)

“…Standard curves obtained by plotting the CT values against the methylation level for the MSP primer set (rDNA Me) were linear, and that for the MIP primer set (Ref) remained constant throughout. (<b>B</b>) A serial dilution of human methylated DNA ranging from 5 pg to 1000 pg was bisulfite-treated and used as the template for qPCR. …”

Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx by Qingguo Liu (9620123)

“…Objectives<p>Stroke is increasingly affecting young adults, with metabolic-risk factors playing a critical role in this trend. This study aims to assess the global burden and trends of stroke and its subtypes attributable to metabolic-risks in young adults from 1990 to 2021.…”

Image_1_Cell Adhesion Molecule Close Homolog of L1 (CHL1) Guides the Regrowth of Regenerating Motor Axons and Regulates Synaptic Coverage of Motor Neurons.TIF by Daria Guseva (191402)

“…Regarding the femoral nerve after injury, CHL1-deficient mice demonstrated preferential motor axon regrowth into the saphenous vs. quadriceps branch after nerve transection upstream of the nerve bifurcation by 8 weeks after transection, indicating decreased preferential motor re-innervation. Furthermore, in injured wild-type mice, enhanced CHL1 expression was observed in regenerating axons in the proximal nerve stump upstream of the bifurcation at days 1, 3, 5, 7 and 14, and in the distal stump at days 7 and 14 after injury, when compared to non-injured mice. …”

Image_2_Both AMP-activated and cAMP-dependent protein kinase regulate the expression of heat shock protein 70-2 gene in Neopyropia yezoensis.tif by Zhenjie Sun (9723659)

“…Here, a full-length sequence of the hsp70-2 gene was cloned and its’ expression regulation was analyzed. …”

Table1_Analysis of factors that influence the occurrence of otitis media with effusion in pediatric patients with adenoid hypertrophy.pdf by Wenjing Chen (383602)

“…Univariate analysis was performed as a basis for logistic regression analysis.</p>Results<p>A total of 511 children (329 boys and 182 girls) were included, their mean age was 5.37 ± 2.10 years. …”

Crosstalk between the Ras/ERK pathway and DENV-induced AMPs. by Wen-Quan Liu (9323021)

“…C6/36 cells were transfected with pIB-Ras for 48h, the pIB-V5 vector was taken as the control. The total RNAs were extracted and the <i>AMPs</i> transcription was analyzed by qPCR. …”