PINK1-deficiency facilitates mitochondrial iron accumulation and colon tumorigenesis by Mariella Arcos (17617599)

“…</p> <p><b>Abbreviation</b>: ANOVA: analysis of variance; APC: adenomatous polyposis coli; cAMP: cyclic adenosine monophosphate; CDX2: caudal type homeobox 2; CGAS: cyclic GMP-AMP synthase; CRC: colorectal cancer; DNA: deoxyribonucleic acid; DFP: deferiprone; DMEM: Dulbecco’s modified Eagle medium; DSS: dextran sodium sulfate; ERT2-Cre: Cre recombinase fused to a triple mutant form of the human estrogen receptor; EV: empty vector; GLB: glybenclamide/glyburide; H&E: hematoxylin and eosin; ICP-MS: inductively coupled plasma mass spectrometer; IL1B: interleukin 1 beta; kDa: kilodalton; MCU: mitochondrial calcium uniporter; MKI67: marker of proliferation Ki-67; mRNA: messenger ribonucleic acid; MTT: 3-(4,5-dimethylthiazol-2-Yl)-2,5-diphenyltetrazolium bromide; NLRP3: NLR family pyrin domain containing 3; OE: overexpression; PBS: phosphate-buffered saline; p-CREB: phosphorylated cAMP responsive element binding protein; PINK1: PTEN induced kinase 1; p-PRKAA/AMPK: phosphorylated protein kinase AMP-activated catalytic subunit alpha; qPCR: qualitative polymerase chain reaction; RNA-seq: ribonucleic acid sequencing; ROS: reactive oxygen species; sg: single guide; sh: short hairpin; SLC25A28: solute carrier family 25 member 28; SLC25A37/MFRN: solute carrier family 25 member 37; STING1: stimulator of interferon response cGAMP interactor 1; TP53/p53: tumor protein p53; TUBA: tubulin alpha; µL: microliter; µm: micrometer; µM: micromolar; mm: millimeter.…”

Attention reduces decision uncertainty under high cognitive demand. by Rahul Garg (3064578)

“…Yellow: increased, dark grey: decreased, light grey: unchanged. (M) Bar plots show the percentage of glomeruli exhibiting a change in response for cued vs. un-cued trials. …”

P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). by Hong Yan Huang (20135965)

“…<p>(A) P4HA3 deficiency inhibited migration and invasion abilities of MDA-MB-231, HCT116 and A549 cell lines by transwell assay. …”

Image_2_Anti-Migratory Effect of Dipotassium Glycyrrhizinate on Glioblastoma Cell Lines: Microarray Data for the Identification of Key MicroRNA Signatures.jpeg by Gabriel Alves Bonafé (6740750)

“…In addition, DPG treatment led to a 100% reduction in sphere formation. The qPCR results in U251 and U138MG cells showed that DPG increased miR-4443 (2.44 vs. 1.11, p-value = 0.11; 8.27 vs. 1.25, p-value = 0.04) and miR-3620 expression (1.66 vs. 1.00, p-value = 0.03; 8.47 vs. 1.01, p-value = 0.03) and decreased CD209 (0.44 vs. 1.10, p-value = 0.03; 0.49 vs. 1.07, p-value = 0.04) and TNC (0.20 vs. 1.03, p-value = 0.001; 0.39 vs. 1.06, p-value = 0.01) mRNA levels compared to controls. …”

Image_1_Anti-Migratory Effect of Dipotassium Glycyrrhizinate on Glioblastoma Cell Lines: Microarray Data for the Identification of Key MicroRNA Signatures.jpeg by Gabriel Alves Bonafé (6740750)

“…In addition, DPG treatment led to a 100% reduction in sphere formation. The qPCR results in U251 and U138MG cells showed that DPG increased miR-4443 (2.44 vs. 1.11, p-value = 0.11; 8.27 vs. 1.25, p-value = 0.04) and miR-3620 expression (1.66 vs. 1.00, p-value = 0.03; 8.47 vs. 1.01, p-value = 0.03) and decreased CD209 (0.44 vs. 1.10, p-value = 0.03; 0.49 vs. 1.07, p-value = 0.04) and TNC (0.20 vs. 1.03, p-value = 0.001; 0.39 vs. 1.06, p-value = 0.01) mRNA levels compared to controls. …”

MSCs inhibit lung edema and inflammatory cells in HS rats. by Shibani Pati (208746)

“…Five sections were analyzed per animal (n = 5) and 8–10 high power fields were counted for fluorescent positive (CD68+) cells. …”

Schematic overview of dynamic proteomics for exploring cell cycle dependent changes in level and localization. by Shlomit Farkash-Amar (121750)

“…(D) Fluorescence traces of individual cells over a 40 hours movie (tagged protein is DDX5). Sharp decreases are at division events (E) In silico synchronization is done by plotting cell dynamics on a time axis which indicates time from previous or next division. …”

Smart Window Based on Electric Unfolding of Microwrinkled TiO₂ Nanometric Films by Milan Shrestha (3959612)

“…In-line transmittance of these optical metasurfaces decreases from 81% to 1.85% under a 4–5% radial compression. …”

S8 Fig - by Luciana López-Jury (8601540)

“…(<b>A</b>) Difference between echolocation context effect when decreasing LF inputs firing rate and increasing LF presynaptic adaptation relative to the respective value obtained with the awake model. …”

Robust SOD3 expression reduced anaplastic thyroid cancer cell growth. by Mikko O. Laukkanen (197270)

“…<p>(a) Real time RT-PCR analysis showed a high-level mRNA production of <i>SOD3</i> transgene in anaplastic thyroid cancer 8505c cells. …”

Table_1_Continuity and changes in grandchild care and the risk of depression for Chinese grandparents: new evidence from CHARLS.docx by Yue Hong (121499)

“…</p>Conclusion<p>Providing continuous low-intensity, decreased-intensity grandparenting and the cessation of caregiving were associated with a decreased level of depression for Chinese grandparents; however, there were complex interactions at play. …”

RCECs p-JNK (I), phosphorylated-NF-κβ (II) and cultured medium IL-1β(III) levels. by Yihui Chen (446576)

“…<p>RCECs cultured in NOP (normal osmotic pressure, 312mOsM) (A), HOP (high osmotic pressure, 500mOsM) (B), HOP+NAC (10 mM) (C), HOP+ DPI (10 µM) (D), HOP+ JNK inhibitor SP600125 (25 µM) (E) and HOP+ NF−kB inhibitor Bay11-7082(5 µM) (F) for 24 h. p-JNK expression in the HOP group was significantly higher than that in the NOP group (<i>P</i><0.01). p-JNK expression in the HOP group added with ROS inhibitor NAC and JNK inhibitor SP600125 was decreased significantly (<i>P</i><0.01) (I). phosphorylated-NF-κβ expression in the HOP group was significantly higher than that in the NOP group (<i>P</i><0.01). phosphorylated-NF-κβ expression in the the HOP group added with ROS inhibitor NAC, DPI and JNK inhibitor SP600125 was decreased significantly (<i>P</i><0.01) (II). …”

Table_1_The association between implementation of multidisciplinary rounds and clinical outcomes.DOCX by Pranati Sreepathy (14055423)

“…Significant increase in the utilization of physical therapy (34.2 to 53.5%; P < 0.01) and dietary services (7.2 to 19.3%; P < 0.01) were observed.…”

Table_1_Anatomical study of single incision contralateral C7 nerve transfer through subdural pathway.DOCX by Long Yao (3765892)

“…Divide the front root into 3 bundles and the rear root into 5 bundles.</p>Result<p>The C7 nerve has a filamentous structure, arranged symmetrically on both sides, and the length of the root fibers gradually shortens from top to bottom. …”

Table_1_Daylength effects on black spruce bud dormancy release change during endo- and ecodormancy.DOCX by Stephen J. Colombo (1761883)

“…The time required for budburst decreased as time after bud initiation increased. Time to terminal budburst also decreased linearly with longer photoperiods. …”

DataSheet1_Physicochemical and adsorptive properties of biochar derived from municipal sludge: sulfamethoxazole adsorption and underlying mechanism.docx by Xiaojie Qiu (114836)

“…Adsorption experiments using the optimized biochar sample of SBC800 resulted in a 95% sulfamethoxazole (SMX) removal efficiency and the maximum adsorption capacity of 7033.4 mg/kg, which was 47.5 times higher than that of SBC300. …”

Image_7_Temporal Bacterial Community Diversity in the Nicotiana tabacum Rhizosphere Over Years of Continuous Monocropping.TIF by Lang Yan (532266)

“…In this study, high-throughput sequencing targeting the 16S rRNA gene phylogenetic marker was performed on 60 soil samples of rhizosphere soil from flue−cured tobacco in the replanting, growth and harvest period across 5, 10, and 20 years of a continuous monocropping system. …”

Presentation_1_Grade-control outdoor turning flight of robo-pigeon with quantitative stimulus parameters.pdf by Ke Fang (700094)

“…The success rate of turning flight control decreases significantly when the stimulation parameters exceed SF > 100 Hz or SD > 5 s. …”

Table_7_Variation in Amygdalin Content in Kernels of Six Almond Species (Prunus spp. L.) Distributed in China.DOCX by Wei Wang (17594)

“…The highest level of amygdalin was detected in Tangut almond, with 5.45–9.73 g/100 g. The other kernels showed a range from 3.14 to 6.80 g/100 g in wild almond and from 3.00 to 4.22 g/100 g in longstalk almond. …”

The Yeast Rab GTPase Ypt1 Modulates Unfolded Protein Response Dynamics by Regulating the Stability of <em>HAC1</em> RNA by Nikoleta G. Tsvetanova (149142)

“…Decreasing expression of the Ypt1 protein resulted in a reduced rate of <em>HAC1</em> RNA decay, leading to significantly increased levels of both unspliced and spliced <em>HAC1</em> RNA, and delayed attenuation of the UPR, when ER stress was relieved. …”