Image1_Paleoclimate Records of the Middle Okinawa Trough Since the Middle Holocene: Modulation of the Low-Latitude Climate.jpg by Lei Liu (5074)

“…In contrast, RI-OH temperatures varied from 17.4 to 26.0°C, showing a lower trend than TEX^H₈₆ SSTs. …”

Presentation_1_Effect of Pelvic Bone Marrow Sparing Intensity Modulated Radiation Therapy on Acute Hematologic Toxicity in Rectal Cancer Patients Undergoing Chemo-Radiotherapy.pptx by Wei Huang (36889)

“…</p>Results<p>The radiation dose to PBM (V₅~V₄₅, D_mean, P<0.05), PBM sub-regions (V₁₀~V₃₅, D_mean, P<0.05) and both femoral heads (V₅~V₄₀, D_mean, P<0.05) decreased significantly in the PBM sparing IMRT group compared with that of the non-PBM sparing IMRT group (P<0.05). …”

Image_3_Postoperative Long-Term Independence Among the Elderly With Meningiomas: Function Evolution, Determinant Identification, and Prediction Model Development.tif by Haoyi Li (593226)

“…Independent risk factors for postoperative long-term non-independence included: advanced age (70–74 vs. 65–69 OR: 2.631; 95% CI: 1.545–4.481 and ≥75 vs. 65–69 OR: 3.833; 95% CI: 1.667–8.812), recurrent meningioma (OR: 7.791; 95% CI: 3.202–18.954), location in the skull base (OR: 2.683; 95% CI: 1.383–5.205), tumor maximal diameter >6 cm (OR: 3.089; 95% CI: 1.471–6.488), nerves involved (OR: 3.144; 95% CI: 1.585–6.235), high risk of WHO grade and biological behavior (OR: 2.294; 95% CI: 1.193–4.408), recurrence during follow-up (OR: 10.296; 95% CI: 3.253–32.585), lower preoperative KPS (OR: 0.964; 95% CI: 0.938–0.991) and decreased KPS on discharge (OR: 0.967; 95% CI: 0.951–0.984) (P < 0.05). …”

Data_Sheet_1_Anti-hyperuricemic and Anti-inflammatory Effects of Marantodes pumilum as Potential Treatment for Gout.docx by Eldiza Puji Rahmi (8584506)

“…The anti-hyperuricemic activity was initially assessed by XO inhibition with a spectrophotometric in vitro assay. The most active extract was further investigated on hyperuricemic rat model induced by potassium oxonate to determine serum uric acid levels and liver XO effect. …”

Data_Sheet_1_Multi-Step Unfolding and Rearrangement of α-Lactalbumin by SDS Revealed by Stopped-Flow SAXS.DOCX by Grethe Vestergaard Jensen (1658311)

“…A protein-surfactant complex is formed within the dead time of mixing (2.5 ms). …”

DataSheet_1_Including Volume Effects in Biological Treatment Plan Optimization for Carbon Ion Therapy: Generalized Equivalent Uniform Dose-Based Objective in TRiP98.pdf by Marco Battestini (12268814)

“…In particular, for a plan containing multiple OARs, we obtained the same target coverage and similar DVHs for OARs with a small volume effect while decreasing the mean dose received by the proximal parotid, thus reducing its NTCP by a factor of 2.5. …”

Molecular regulation of miR-378 on the development of mouse follicle and the maturation of oocyte in vivo by Xiao-Feng Sun (149119)

“…The results showed that CMV-miR-378 lentivirus transduction in the mouse ovaries resulted in reduced ovary size, extended oestrous cycle (6-7 d in miR-378 overexpression group and 4–5 dyas in GFP control group) due to continuous oestrum, decreased percentage of oocytes in vitro maturation rate (IVM 60.8% vs. 89.4% in GFP control), increased apoptosis rate (Bax/Bcl2 in mRNA and protein level), decreased expression of genes associated with gap junction, such as connexin 43 (Cx-43) and connexin (Cx-37) and decreased expression of genes associated with follicular development, such as BMP15 and GDF9. …”

Constitutive heterochromatin controls nuclear mechanics, morphology, and integrity through H3K9me3 mediated chromocenter compaction, Manning et al raw data by Gianna Manning (19858309)

“…Nuclear stiffness increases upon loss of H3K9me2 and decreases upon loss of H3K9me3.</b></p><p dir="ltr"><b>Figure 5. …”

Alternative splicing events affecting PTPRC exons 4 to 7. by Charlotte Vandermeulen (11457794)

“…(B) Increased inclusion of exon 4. Decreased inclusion of exon 5 (C), 6 (D) and 7 (E). …”

Overlap of epigenetic signatures and Hi-C contacts. by Ittai E. Eres (7010684)

“…<p>(A) Hi-C loci that do not make contact with promoters are ranked in order of decreasing DC FDR (x-axis). …”

DataSheet_1_Characterization of 3D heterocellular spheroids of pancreatic ductal adenocarcinoma for the study of cell interactions in the tumor immune microenvironment.docx by Giulio Giustarini (16544991)

“…Further, 4-culture tumor spheroids decreased the concentrations of T-cell chemoattracting cytokines, i.e., CCL4, CCL5, and CXCL9, when compared with the non-cancerous spheroids, revealing a critical immunosuppressive feature of the different types of cells forming the tumor spheroids. …”

Predictors in ordinal regression model for GDS. by Shane Naidoo (20148021)

“…</p><p>Results</p><p>The sample had a mean BMI of 27.53 kg/m² (95% CI [26.99, 28.07], SD = 5.49), with an obesity prevalence of 31.82%. …”

Video_7_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

RACK1_Y246F impairs the binding of ZBP1 and Src kinase to ribosomes and reduces the release and translation of β-actin mRNA. by Marcello Ceci (161143)

“…<b>D</b>, The level of β-actin mRNA, measured by qRT-PCR, on RNA isolated from non translating fractions (fractions 2–3 of ribosomal profile reported in <b>A</b>) and from polysomal fractions (fractions 5–8) was decreased in GFP-RACK1_Y246F/Flag-ZBP1 cells, as compared to that of GFP-RACK1_wt/Flag-ZBP1 expressing cells. …”

Emulsion Solvent Evaporation-Induced Self-Assembly of Block Copolymers Containing pH-Sensitive Block by Yuqing Wu (628490)

“…Interestingly, when pH was further decreased to ∼2.5, interfacial instability of the emulsion droplets was observed, and each emulsion droplet generated nanoscale assemblies including vesicles, worm-like and/or spherical micelles rather than a nanostructured microparticle. …”

Application of Ion Torrent Sequencing to the Assessment of the Effect of Alkali Ballast Water Treatment on Microbial Community Diversity by Masanori Fujimoto (629927)

“…<div><p>The impact of NaOH as a ballast water treatment (BWT) on microbial community diversity was assessed using the 16S rRNA gene based Ion Torrent sequencing with its new 400 base chemistry. …”

Video_3_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Video_1_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.MPG by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Image 1_Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis.tif by Shu-Qin Ding (9319682)

“…Pro-inflammatory cytokines (Ifng, Il17a, Il1b, Il6) decreased, while anti-inflammatory markers (Arg1, Tgfb1) rose. …”

Table_2_Colorectal cancer among inflammatory bowel disease patients: risk factors and prevalence compared to the general population.DOCX by Naim Abu-Freha (13894376)

“…</p>Results<p>During a follow-up of 139,448 years among Crohn’s disease (CD) patients and 139,533 years among ulcerative colitis (UC) patients, a frequency rate of CRC was 1.5% (191) among 12,888 CD patients and 2.1% (261) among 12,381 UC patients compared to 1.2% among 57,334 controls. …”