FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…(B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC₅₀ = 6.4 μM, p ≤ 0.05). (C) HuH6 cells were plated and allowed to reach 80% confluence, at which time the media was changed for fresh media (0, 5, or 8 μM FTY720) and a standard scratch wound was made. …”

(a) Decreased PYK2 expression, Tyr402 and ERK1/2 activations and migration of A549 cells were observed by SOCS3 up-regulation by Siyang Zhang (93223)

Decrease of cell viability and alterations of cell membrane permeability by infection with rotavirus isolates. by Carlos A. Guerrero (1264551)

Administration of APB5, but not APA5, decreases the hyperplasia of alveolar type 2 epithelial cells induced by BLM. by Masami Kishi (6167105)

“…The administration of APB5 markedly decreased the hyperplasia of type 2 epithelial cells induced by BLM. …”

Archazolid decreases the activity and expression of cathepsin B in endothelial cells. by Betty Luong (5738027)

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”

Effects of PD98059 in SNAP- induced decreased expression of Giα-2 and Giα-3 proteins in aortic VSMC from 12-week old SHR and age-matched WKY rats. by Oli Sarkar (4236406)

Detection of epistasis is confined in a time window whose width is controlled by the mean selection coefficient. by Gabriele Pedruzzi (5753792)

Cardamonin induced apoptosis and decreased the MMP of ovarian cancer cells. by Peiguang Niu (17044532)

FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia by Xiaofeng Wang (119575)

“…Furthermore, we found that FGFR3 interacted with ATG12–ATG5 conjugate by binding to ATG5. More intriguingly, FGFR3 signaling was found to decrease the protein level of ATG12–ATG5 conjugate. …”

Enkephalin-encoding herpes simplex virus-1 decreases inflammation and hotplate sensitivity in a chronic pancreatitis model-5 by Hong Yang (37298)

Lung cancer cell lines secrete BMP2 and knockdown of BMP2 decreases BMP signaling and induces cell death. by Elaine Langenfeld (402034)

“…(<b>D</b>) Western blot analysis of H1299 cells in SFM 48 hours after being transfected with control siRNA or siRNA targeting BMP2. BMP2 knockdown causes a decrease in expression of pSmad 1/5 and Id1. …”

Botulinum toxin A (3.5 U/kg) decreases mechanical allodynia induced by IoNC- injury in rats. by Boris Filipović (336089)

Decreased HIF levels associated with hyperoxic cell state. by Julie M. Koeman (108185)

“…<p>(A) Normalized densitometry of HIF-1α protein levels (•),HIF-1β protein levels (▴), and HIF-1 DNA-binding activity (⧫) as presented in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000176#pgen-1000176-g005" target="_blank">Figure 5B</a> of the Jiang et al. article. …”

Dietary zinc repletion decreases Zip10 expression. by Louis A. Lichten (215913)

“…Values are given as means ± SD. Values with a different superscript are significantly different at <i>P</i><0.05 or greater, <i>n</i> = 5. …”

Decreasing the front-to-rear difference of myosin II activity induced the collapse of leading front and reversed soma translocation of Schwann cells. by Ying Wang (11406)

Decrease of Paneth cells and goblet cells in small intestine upon deletion of TNKSs. by Pan Ye (2902336)

IODVA1 inhibits lamellipodia and circular dorsal ruffle (CDR) formation in MDA-MB-231 cells and decreases Rac activation. by Anjelika Gasilina (8566296)

Decrease of mitochondrial membrane potential by silvestrol. by Takayuki Kogure (235048)

METH decreased basal pERK1/2 levels and potentiated ERK1/2 phosphorylation induced by 6-OHDA. by Amina El Ayadi (341955)

“…METH decreased activation of ERK 1/2 in a concentration-dependent manner (0, 0.5, and 1 mM at the 24 hr time point) and enhanced the activation of ERK1/2 after 6-OHDA exposure. …”