TNIP1 abrogates the profibrotic effects of proinflammatory cytokines on collagen synthesis by SSc fibroblatsts. by Yannick Allanore (58641)

“…<p>(A,B) SSc dermal fibroblasts treated with recombinant TNFa or IL1β and incubated 24 hours with TNIP1 displayed decreased mRNA levels for (A) <i>COL1A1</i> (1.6 and 1.5-fold reduction, <i>P</i> = 0.02 and 0.04, respectively) and (B) <i>COL1A2</i> (1.7 and 1.8-fold reduction, <i>P</i> = 0.02 and 0.009, respectively). …”

TNIP1 abrogates the profibrotic effects of proinflammatory cytokines on collagen synthesis by healthy fibroblatsts. by Yannick Allanore (58641)

“…<p>(A,B) Healthy dermal fibroblasts treated with recombinant Il1β or Il6 and incubated 24 hours with TNIP1 displayed decreased mRNA levels for (A) <i>COL1A1</i> (1.6 and 1.4-fold reduction, <i>P</i> = 0.01 and 0.03, respectively) and (B) <i>COL1A2</i> (1.7 and 1.6-fold reduction, <i>P</i> = 0.02 and 0.03, respectively). …”

Optimizing replay intensity and resolution in aberration-compensated off-axis holograms by ambient humidity control by Henry Nebrensky (1229277)

“…Roderic Lakes extracted using <a href="http://www.unige.ch/sciences/chifi/cpb/windig.html">WinDIG</a> version 2.5.…”

Functional Polymorphisms in the <em>TERT</em> Promoter Are Associated with Risk of Serous Epithelial Ovarian and Breast Cancers by Jonathan Beesley (89897)

“…<div><p>Genetic variation at the <em>TERT-CLPTM1L</em> locus at 5p15.33 is associated with susceptibility to several cancers, including epithelial ovarian cancer (EOC). …”

Table_2_The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing.docx by Léa Chantal Tran (12471495)

“…We aimed to identify differences in the metabolome of DM after two types of milk sterilization: the Holder pasteurization (HoP) and a high hydrostatic pressure (HP) processing. DM samples were sterilized by HoP (62.5°C for 30 min) or processed by HP (350 MPa at 38°C). 595 milk metabolites were analyzed using an untargeted metabolomic analysis. …”

Table_3_The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing.docx by Léa Chantal Tran (12471495)

“…We aimed to identify differences in the metabolome of DM after two types of milk sterilization: the Holder pasteurization (HoP) and a high hydrostatic pressure (HP) processing. DM samples were sterilized by HoP (62.5°C for 30 min) or processed by HP (350 MPa at 38°C). 595 milk metabolites were analyzed using an untargeted metabolomic analysis. …”

Table_8_The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing.docx by Léa Chantal Tran (12471495)

“…We aimed to identify differences in the metabolome of DM after two types of milk sterilization: the Holder pasteurization (HoP) and a high hydrostatic pressure (HP) processing. DM samples were sterilized by HoP (62.5°C for 30 min) or processed by HP (350 MPa at 38°C). 595 milk metabolites were analyzed using an untargeted metabolomic analysis. …”

Table_4_The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing.docx by Léa Chantal Tran (12471495)

“…We aimed to identify differences in the metabolome of DM after two types of milk sterilization: the Holder pasteurization (HoP) and a high hydrostatic pressure (HP) processing. DM samples were sterilized by HoP (62.5°C for 30 min) or processed by HP (350 MPa at 38°C). 595 milk metabolites were analyzed using an untargeted metabolomic analysis. …”

Table_1_The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing.docx by Léa Chantal Tran (12471495)

“…We aimed to identify differences in the metabolome of DM after two types of milk sterilization: the Holder pasteurization (HoP) and a high hydrostatic pressure (HP) processing. DM samples were sterilized by HoP (62.5°C for 30 min) or processed by HP (350 MPa at 38°C). 595 milk metabolites were analyzed using an untargeted metabolomic analysis. …”

Table_6_The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing.docx by Léa Chantal Tran (12471495)

“…We aimed to identify differences in the metabolome of DM after two types of milk sterilization: the Holder pasteurization (HoP) and a high hydrostatic pressure (HP) processing. DM samples were sterilized by HoP (62.5°C for 30 min) or processed by HP (350 MPa at 38°C). 595 milk metabolites were analyzed using an untargeted metabolomic analysis. …”

Table_7_The metabolome of human milk is altered differentially by Holder pasteurization and high hydrostatic pressure processing.docx by Léa Chantal Tran (12471495)

“…We aimed to identify differences in the metabolome of DM after two types of milk sterilization: the Holder pasteurization (HoP) and a high hydrostatic pressure (HP) processing. DM samples were sterilized by HoP (62.5°C for 30 min) or processed by HP (350 MPa at 38°C). 595 milk metabolites were analyzed using an untargeted metabolomic analysis. …”

The synthetic lethality of the <i>erd1</i>Δ mutation with the Neo1p-depleted <i>cfs1</i>Δ mutation is not caused by reduced levels of cytoplasmic Pi. by Mamoru Miyasaka (9187916)

“…Cells were grown and spotted, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0236520#pone.0236520.g001" target="_blank">Fig 1B</a>, in YPGA (galactose) or YPDA (glucose) medium with either 20 mM Pi or 50 mM Pi and then incubated at 30°C for 1.5 d. …”

Model for the adaptive pathogenicity of <i>S</i>. Typhimurium to the host environment via the sequential modulation of RNase III and RNase G endoribonucleolytic activity. by Minho Lee (50566)

“…H-NS usually represses <i>hilA</i> gene expression; however, decreased cellular H-NS levels appear to activate the <i>hilA</i> promoter. …”

Nickel (ii) effects on Anammox reaction: reactor performance, dehydrogenase, sludge morphology and microbial community changes by Jian Cheng (48763)

“…The results showed that when the concentration of Ni²⁺ was 0.5 mg/L, the bioreactor had the highest denitrification efficiency, while the removal efficiency of ammonia nitrogen and nitrite nitrogen gradually decreased at concentrations higher than 2 mg/L, and the removal rates of ammonia nitrogen and nitrite nitrogen were 26% and 39.81% at the end of the experiment, respectively. …”

Exposure to Perfluorooctane Sulfonate In Utero Reduces Testosterone Production in Rat Fetal Leydig Cells by Binghai Zhao (509145)

“…<div><p>Background</p><p>Perfluorooctane sulfonate (PFOS) is a synthetic material that has been widely used in industrial applications for decades. …”

Differential gene GO enrichment analysis. by Jing Li (10611)

“…The results obtained were as follows: (1) Short-term low concentration of Cd stress (20 mg/kg) had a transient promotion effect on the growth of sisal roots, but Cd showed a significant inhibitory effect on the growth of sisal roots over time. (2) Under different concentrations of Cd stress, the Cd content in sisal root was greater than that in sisal leaf, and Cd accumulated mainly in sisal roots. (3) With the increase of Cd stress concentration, the antioxidant enzyme catalase activity increased, peroxidase activity showed a decreasing trend, and superoxide dismutase showed a trend of increasing and then decreasing. (4) Transcriptome sequencing analysis detected 123 differentially expressed genes (DEGs), among which 85 genes were up-regulated and 38 genes were down-regulated. …”

RNA sequencing results. by Jing Li (10611)

“…The results obtained were as follows: (1) Short-term low concentration of Cd stress (20 mg/kg) had a transient promotion effect on the growth of sisal roots, but Cd showed a significant inhibitory effect on the growth of sisal roots over time. (2) Under different concentrations of Cd stress, the Cd content in sisal root was greater than that in sisal leaf, and Cd accumulated mainly in sisal roots. (3) With the increase of Cd stress concentration, the antioxidant enzyme catalase activity increased, peroxidase activity showed a decreasing trend, and superoxide dismutase showed a trend of increasing and then decreasing. (4) Transcriptome sequencing analysis detected 123 differentially expressed genes (DEGs), among which 85 genes were up-regulated and 38 genes were down-regulated. …”

Table 6_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Presentation_1_Heat Stress Altered the Vaginal Microbiome and Metabolome in Rabbits.pdf by Yu Shi (117923)

“…Among them, the endocrine hormone estradiol (E₂) increased in the Heat group and was positively associated with a number of metabolites such as linolelaidic acid (C18:2N6T), N-acetylsphingosine, N-oleoyl glycine, trans-petroselinic acid, syringic acid, 2-(1-adamantyl)-1-morpholinoethan-1-one, 5-OxoETE, and 16-heptadecyne-1,2,4-triol. …”

Long-Term Trends of Per- and Polyfluoroalkyl Substances (PFAS) in Suspended Particular Matter from German Rivers Using the Direct Total Oxidizable Precursor (dTOP) Assay by Bernd Göckener (7527578)

“…Trends based on target analysis (∑PFCA_target: −10.0%, ∑PFSA_target: −8.2%) were more pronounced than in the dTOP analysis (∑PFCA_dTOP: −4.2%; ∑PFSA_dTOP: −5.3%), suggesting that conventional target analysis overestimated actual decreases as precursors are not considered. …”