Data_Sheet_1_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.PDF by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Table_1_Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease.DOCX by Jie Zhou (28945)

“…Weighted multivariate COX regression models, restricted cubic splines (RCS) models, and stratified analyses were used to investigate the association of PHQ-9 scores and ALI with all-cause mortality.</p>Results<p>During a median follow-up of 5.8 years (interquartile range 3.4–8.6 years), a total of 985 patients died (25.0%). …”

Table 2_Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis.xlsx by Shu-Qin Ding (9319682)

“…Pro-inflammatory cytokines (Ifng, Il17a, Il1b, Il6) decreased, while anti-inflammatory markers (Arg1, Tgfb1) rose. …”

Data_Sheet_2_In silico Description of LAT1 Transport Mechanism at an Atomistic Level.PDF by Luca Palazzolo (5681993)

“…<p>The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine (DIT), a well-known LAT1 inhibitor. …”

Ischemic Acute Kidney Injury Perturbs Homeostasis of Serine Enantiomers in the Body Fluid in Mice: Early Detection of Renal Dysfunction Using the Ratio of Serine Enantiomers by Jumpei Sasabe (516628)

“…In the serum, the level of D-serine gradually increased after renal IRI in parallel with that of creatinine, whereas the L-serine level decreased sharply in the early phase after IRI. The increase of D-serine was suppressed in part by genetic inactivation of a D-serine-degrading enzyme, D-amino acid oxidase (DAO), but not by disruption of its synthetic enzyme, serine racemase, in mice. …”

Table_3_Genome-Wide Identification of Rapid Alkalinization Factor Family in Brassica napus and Functional Analysis of BnRALF10 in Immunity to Sclerotinia sclerotiorum.xlsx by Yu-Han He (12004193)

“…The oilseed rape genome carried 61 RALFs, half of them were atypical, containing a less conserved YISY motif and lacking a RRXL motif or a pair of cysteines. …”

An outbreak of HIV infection among people who inject drugs linked to injection of propofol in Taiwan by Yu-Ching Huang (815925)

“…The HIV epidemic curve among PWID revealed an outbreak of 82 in 2015, which then decreased to 43 in 2016 after propofol began to be regulated as a Schedule 4 controlled drug in August 2015. …”

Table_2_Colorectal cancer among inflammatory bowel disease patients: risk factors and prevalence compared to the general population.DOCX by Naim Abu-Freha (13894376)

“…</p>Results<p>During a follow-up of 139,448 years among Crohn’s disease (CD) patients and 139,533 years among ulcerative colitis (UC) patients, a frequency rate of CRC was 1.5% (191) among 12,888 CD patients and 2.1% (261) among 12,381 UC patients compared to 1.2% among 57,334 controls. …”

Table 4_Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis.xlsx by Shu-Qin Ding (9319682)

“…Pro-inflammatory cytokines (Ifng, Il17a, Il1b, Il6) decreased, while anti-inflammatory markers (Arg1, Tgfb1) rose. …”

Consortial population relaxation oscillator. by James J. Winkle (7181861)

“…<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009381#pcbi.1009381.g005" target="_blank">Fig 5B</a>). …”

Data_Sheet_1_Petrogenesis of the Late Oligocene Takht batholith, Southeastern Iran: Implications for the Diachronous Nature of the Arabia–Eurasia Collision.PDF by Kwan-Nang Pang (9266600)

“…Overall, our results indicate that the Takht batholith is a Cordilleran-type batholith formed beneath a continental or transitional arc of normal crustal thickness. …”

Liver tissue viability. by Peter Onody (50458)

“…The data are presented as means+SEM. ¤ <0.05 versus “early” control group; &p<0.05 versus sham-operated group; $ p<0.05 versus “early” IR group; #p<0.05 versus “late” control group; * p<0.05 versus “late” IR group. n = 5 in sham-operated (S) and control groups (C_E, C_L); n = 10 in IR (IR_L, IR_E) and levosimendan pretreated groups (L_E, L_L).…”

DataSheet4_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.ZIP by Yi-Chun Su (17473050)

“…Our results reveal that treating human osteoblasts with 0.5 μg/mL biphasic calcium phosphate nanomaterials results in a marked increase in alkaline phosphatase (ALP) activity and the upregulation of osteogenesis-related genes. …”

DataSheet1_Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota.PDF by Zuoyuan Wang (13247373)

“…Finasteride, a competitive and specific inhibitor of type II 5a-reductase, has been reported recently to be able to downregulate plasma TMAO level thus preventing the onset of atherosclerosis by our research group. …”

Poloxamer/Poly(ethylene glycol) Self-Healing Hydrogel for High-Precision Freeform Reversible Embedding of Suspended Hydrogel by Arthur Colly (10508947)

“…The usefulness of this approach is distinctly demonstrated through a six-axis printing of a highly complex silicone anatomical model. …”

Molecular epidemiology of HIV-1 infection among men who have sex with men in Taiwan from 2013 to 2015 by Wei-You Li (3686827)

“…The annual prevalence and incidence of HIV-1 showed a downward trend from 2013 to 2015 (6.56%, 5.97 per 100 person-years in 2013; 4.53%, 3.97 per 100 person-years in 2014; 1.84%, 2.08 per 100 person-years in 2015). …”

Image_1_Two Aquaporin Genes, GhPIP2;7 and GhTIP2;1, Positively Regulate the Tolerance of Upland Cotton to Salt and Osmotic Stresses.TIF by Anhui Guo (9376225)

“…<p>Aquaporins (AQPs) facilitate the transport of water and small molecules across intrinsic membranes and play a critical role in abiotic stresses. In this study, 111, 54, and 56 candidate AQP genes were identified in Gossypium hirsutum (AD₁), Gossypium arboreum (A₂), and Gossypium raimondii (D₅), respectively, and were further classified into five subfamilies, namely, plasma intrinsic protein (PIP), tonoplast intrinsic protein (TIP), nodulin 26-like intrinsic protein (NIP), small basic intrinsic protein (SIP), and uncategorized X intrinsic protein (XIP). …”

Table_2_Two Aquaporin Genes, GhPIP2;7 and GhTIP2;1, Positively Regulate the Tolerance of Upland Cotton to Salt and Osmotic Stresses.xls by Anhui Guo (9376225)

“…<p>Aquaporins (AQPs) facilitate the transport of water and small molecules across intrinsic membranes and play a critical role in abiotic stresses. In this study, 111, 54, and 56 candidate AQP genes were identified in Gossypium hirsutum (AD₁), Gossypium arboreum (A₂), and Gossypium raimondii (D₅), respectively, and were further classified into five subfamilies, namely, plasma intrinsic protein (PIP), tonoplast intrinsic protein (TIP), nodulin 26-like intrinsic protein (NIP), small basic intrinsic protein (SIP), and uncategorized X intrinsic protein (XIP). …”

Antioxidants Abrogate Alpha-Tocopherylquinone-Mediated Down-Regulation of the Androgen Receptor in Androgen-Responsive Prostate Cancer Cells by Alexandra M. Fajardo (3176451)

“…TQ pretreatment was also found to inhibit AR activation as measured using the Multifunctional Androgen Receptor Screening assay. Furthermore, TQ decreased androgen-responsive gene expression, including TM4SF1, KLK2, and PSA over 5-fold, whereas AT did not affect the expression of androgen-responsive genes. …”

Herbivore-induced defence response in the brown seaweed <i>Fucus vesiculosus</i> (Phaeophyceae): temporal pattern and gene expression by Markus Molis (220755)

“…Microarray hybridizations investigating the expression of genes 3 days before, as well as at the same time as, feeding assays revealed a decreased palatability of previously grazed <i>F. vesiculosus</i> pieces compared with non-grazed control pieces. …”