Image1_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.JPEG by Yi-Chun Su (17473050)

“…Our results reveal that treating human osteoblasts with 0.5 μg/mL biphasic calcium phosphate nanomaterials results in a marked increase in alkaline phosphatase (ALP) activity and the upregulation of osteogenesis-related genes. …”

Diurnal Expression Pattern, Allelic Variation, and Association Analysis Reveal Functional Features of the <i>E1</i> Gene in Control of Photoperiodic Flowering in Soybean by Hong Zhai (524629)

“…The basal expression level of <i>E1</i> was enhanced by the long light phase, and decreased by duration of dark. We identified a 5bp (3 SNP and 2-bp deletion) mutation, referred to an <i>e1-b3a</i>, which occurs in the middle of B3 domain of the <i>E1</i> gene in the early flowering cultivar Yanhuang 3. …”

Table_3_Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.xlsx by Georgia Papapavlou Lingehed (13174338)

“…Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3^rd trimester, followed by a transient exacerbation after delivery. …”

Table_4_Aberrant expression of bone morphogenetic proteins in the disease progression and metastasis of breast cancer.docx by Ming Liu (105953)

“…BMPs also play dual roles in tumour growth and metastasis of BC.</p>Conclusion<p>A shift pattern of BMPs was showed in different subtypes of breast cancer suggesting a subtype specific involvement. …”

Image7_Integrative analysis of the role of BOLA2B in human pan-cancer.TIF by Mingxing Liang (11361621)

“…Post-transcriptional modifications, including m5C, m1A, and m6A, were observed to regulate BOLA2B expression in all cancers. …”

Parallel, High-Quality Proteomic and Targeted Metabolomic Quantification Using Laser Capture Microdissected Tissues by Shichen Shen (1392565)

“…The strategy features: (i) an optimized molecular weight cutoff (MWCO) filter-based separation of proteins and small-molecule fractions with high and consistent recoveries; (ii) microscale derivatization and charge-based enrichment for ultrasensitive quantification of key androgens (LOQ = 5 fg/1k cells) with excellent accuracy/precision; (iii) reproducible/precise proteomics quantification with low-missing-data using a detergent-cocktail-based sample preparation and an IonStar pipeline for reproducible and precise protein quantification with excellent data quality. …”

DataSheet_1_The impact of female BMI on sperm DNA damage repair ability of oocytes and early embryonic development potential in intracytoplasmic sperm injection cycles.docx by Yuqing Jiang (13241827)

“…However, in the overweight/obese women group, couples with a sperm DFI≥30% had a significantly lower fertilization rate (76% vs. 72.7%; p=0.027), cleavage rate (98.7% vs. 97.2%; p=0.006), and high-quality embryo rate (67.8% vs. 62.6%; p=0.006) than couples with a sperm DFI<30%.…”

Table_2_Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.xlsx by Georgia Papapavlou Lingehed (13174338)

“…Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3^rd trimester, followed by a transient exacerbation after delivery. …”

Image_1_Coenzyme Q10 or Creatine Counteract Pravastatin-Induced Liver Redox Changes in Hypercholesterolemic Mice.PDF by Ana C. Marques (149564)

“…We observed that pravastatin induced higher H₂O₂ production rate (40%), decreased activity of aconitase (28%), a superoxide-sensitive Krebs cycle enzyme, and increased susceptibility to Ca²⁺-induced MPT (32%) in liver mitochondria. …”

Spatial Variation of Phosphorous Retention Capacity in Subsurface Flow Constructed Wetlands: Effect of Wetland Type and Inflow Loading by Guangwei Yu (776189)

“…The values in 6 parts of areas ranged from 0.138 g·kg^-1 to 2.710 g·kg^-1, which also were from -33.5% to 1209% compared to the control value. On contrast, spatial difference of TP content in substrates of VSSF CWs was insignificant, with a variation ranging from 0.776 g·kg^-1 to 1.080 g·kg^-1, that was 275% to 421% higher than the control value. …”

Table_3_Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.xlsx by Georgia Papapavlou Lingehed (13174338)

“…Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3^rd trimester, followed by a transient exacerbation after delivery. …”

Data Sheet 1_Quantitative MRCP metrics as imaging biomarkers to differentiate benign from malignant bile duct obstructions.docx by Kulyada Eurboonyanun (12548926)

“…If detected early, surgical resection carries a 35% 5-year survival rate; this decreases to <11% 1-year survival rate when detected at later stages. …”

On the Viability of Heterolytic Peptide N–C_α Bond Cleavage in Electron Capture and Transfer Dissociation Mass Spectrometry by Matthew D. Wodrich (1344918)

“…Recently, we introduced the “enol” mechanism, which proposes that a backbone N–C_α bond located to the N-terminal (left) side of an aminoketyl radical is cleaved heterolytically. …”

Image_1_Educational and Exercise Intervention to Prevent Falls and Improve Participation in Subjects With Neurological Conditions: The NEUROFALL Randomized Controlled Trial.jpeg by Davide Cattaneo (173579)

“…</p><p>Results: Over a median (Interquartile Range) follow-up of 189 (182–205) days, [EG = 188 (182–202), CG = 189 (182–209)] fallers were 10 in the CG and 11 in the EG (hazard ratio 0.95, 95% confidence interval (CI) 0.45 to 2.5; P = 0.94). …”

Evidence of the Giant Barocaloric Effect in the PVA-Slime System by Molecular Dynamics Simulations by Richard Javier Caraballo-Vivas (22113727)

Supplementary Material for: Single-Center Noninferiority Randomized Trial on the Efficacy and Safety of Low- and High-Dose Rush Oral Milk Immunotherapy for Severe Milk Allergy by Takaoka Y. (4761996)

“…<b><i>Introduction:</i></b> Oral immunotherapy (OIT) has been reported to be effective but associated with a risk of severe symptoms. Thus, an OIT method with decreased risk is required. …”

Data_Sheet_1_Urinary CD8+HLA-DR+ T Cell Abundance Non-invasively Predicts Kidney Transplant Rejection.docx by Emil Grothgar (13048884)

“…<p>Early detection of kidney transplant (KT) rejection remains a challenge in patient care. Non-invasive biomarkers hold high potential to detect rejection, adjust immunosuppression, and monitor KT patients. …”

Table_1_Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy.xlsx by Georgia Papapavlou Lingehed (13174338)

“…Pregnancy represents a natural modulation of the disease course, where the relapse rate decreases, especially in the 3^rd trimester, followed by a transient exacerbation after delivery. …”

Table_1_High-Frequency Hearing Loss Is Associated With Anxiety and Brain Structural Plasticity in Older Adults.pdf by Wen Ma (446751)

“…Our results found gray matter volume (GMV) decreased in 20 brain regions in the ARHL group compared with the NH group, and a positive correlation existed between high-frequency pure tone audiometry (H-PT) and anxiety scores in the ARHL group. …”

Enhancement of Anti-Inflammatory Activity of <i>Aloe vera</i> Adventitious Root Extracts through the Alteration of Primary and Secondary Metabolites via Salicylic Acid Elicitation by Yun Sun Lee (498030)

“…Transcript accumulation analysis of polyketide synthase genes and gas chromatography mass spectrometry showed that these secondary metabolic changes resulted from increased expression of octaketide synthase genes and decreases in malonyl-CoA, which is the precursor for the tricyclic aromatic quinone biosynthesis pathway. …”