One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease - Fig 3 by Behzad Najafian (299389)

“…However, occasional podocytes showed no GL3 inclusions (Ø); <b>(C)</b>Total volume of GL3 inclusions per podocytes V(Inc/PC) was reduced after 11–12 months of ERT (p = 0.02); <b>(D)</b> Podocyte GL3 score (semiquantitative [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152812#pone.0152812.ref014" target="_blank">14</a>]) did not reduce significantly after 11–12 months (follow-up) of ERT (p = 0.18); <b>(E)</b> Podocyte volume significantly decreased after 11–12 months of ERT compared to baseline (p = 0.02). …”

Prb1 overexpression promoted APC entry into vacuoles in <i>vps21Δ</i> cells (but not in <i>ypt1ts</i> and <i>ypt7Δ</i> cells) after nitrogen starvation. by Zulin Wu (4451572)

“…<p><b>A.</b> The accumulation of GFP-Atg8-labeled APCs in <i>vps21Δ</i> cells decreased after Prb1 overexpression. …”

Rate of ATP consumption by tumor cells can modulate the preference for aerobic glycolysis versus oxidative phosphorylation. by Shubham Tripathi (5479454)

“…The behavior shown is representative of that reported by te Boekhorst <i>et al</i>. [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009841#pcbi.1009841.ref035" target="_blank">35</a>] (see <i>Fig 5E</i> therein). …”

DataSheet1_Case report: further delineation of AEBP1-related Ehlers–Danlos Syndrome (classical-like EDS type 2) in an additional patient and comprehensive clinical and molecular re... by Tomomi Yamaguchi (6843290)

“…A next-generation sequencing panel-based analysis revealed compound heterozygous variants in AEBP1: NM_001129.5:c.[2296G>T]; [2383dup], p.…”

Data_Sheet_1_Interaction of energy and sulfur microbial diet and smoking status with polygenic variants associated with lipoprotein metabolism.PDF by Haeng Jeon Hur (6808157)

“…The risk alleles of CETP_rs708272 and ALDH1A2_rs588136 were linked to increased expression in the heart and decreased in the brain, respectively. …”

Data Sheet 2_Bevacizumab and anlotinib combination therapy acts via HIF-1α suppression to exert synergistic anti-angiogenic and anti-tumor effects in non-small cell lung cancer.pdf... by Nafeisha Simayi (22262161)

“…B+A inhibited cell viability by 78%, colony formation by 90%, and invasion by 75% in NSCLC cell lines A549 and H1299; downregulated N-cadherin 5.34-fold, vimentin 6.46-fold, and α-SMA 4.35-fold; and upregulated E-cadherin 3.75-fold. …”

Image_1_Diabetic and Elder Patients Experience Superior Cardiovascular Benefits After Gastric Bypass Induced Weight Loss.JPEG by Pedro R. Pereira (6016460)

“…Weight loss improves CV risk factors and the efficacy of bariatric surgery in decreasing CV mortality is now well-established. Our aim was to assess CV risk progression and occurrence of CV events in a cohort of patients that underwent Roux-en-Y gastric bypass (RYGB) for obesity treatment in a single academic public center.…”

Nano-ciprofloxacin/meropenem exhibit bactericidal activity against Gram-negative bacteria and rescue septic rat model supplementary data by Safy Hadiya (9463872)

“…Synergy was evidenced for CS<b>/</b>Plu-Cip<b>/</b>Mer with a bactericidal effect (at 1<b>× </b>MIC and sub-MICs), and it significantly decreased bacterial load and rescued infected rats. …”

Data Sheet 1_Bevacizumab and anlotinib combination therapy acts via HIF-1α suppression to exert synergistic anti-angiogenic and anti-tumor effects in non-small cell lung cancer.zip... by Nafeisha Simayi (22262161)

“…B+A inhibited cell viability by 78%, colony formation by 90%, and invasion by 75% in NSCLC cell lines A549 and H1299; downregulated N-cadherin 5.34-fold, vimentin 6.46-fold, and α-SMA 4.35-fold; and upregulated E-cadherin 3.75-fold. …”

Data_Sheet_1_MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.pdf by Xiang Wang (127867)

“…The values of IL-6, E-selectin, and ICAM-1 mRNA expressions decreased, while the value of IL-6ST was increased between the agonist treated mice and KD mice. …”

Data_Sheet_1_MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.pdf by Xiang Wang (127867)

“…The values of IL-6, E-selectin, and ICAM-1 mRNA expressions decreased, while the value of IL-6ST was increased between the agonist treated mice and KD mice. …”

<i>pqn-59</i> depletion corrects the reduction of mature <i>lin-4</i> and <i>let-7</i> miRNA levels observed in <i>alg-1(0)</i> mutants and has little effect on the expression of c... by Colleen Carlston (11740725)

Viral RNA burden of disease-associated tissues was quantified using nucleocapsid qPCR. by Katherine S. Lee (13248894)

“…<p>Viral RNA was detectable in the lung tissue of challenged mice from both variants at both timepoints compared to no challenge (One-Way ANOVA, left to right: <i>P =</i> 0.0082, 0.0011, 0.0008, 0.0029) (A). In Nasal Wash, viral RNA burden increased from both variants at Day 2 compared to no challenge (One-Way ANOVA, <i>P =</i> 0.0016 Alpha; <i>P =</i> 0.0030 Delta) and was decreased at Day 6 for both variants from copy numbers at Day 2 (One-Way ANOVA, <i>P</i> = 0.0043 Alpha; <i>P =</i> 0.0019 Delta) with no statistical difference between variants at each time point (B). …”

Table 1_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.xlsx by Ying Liu (18461)

“…</p>Conclusion<p>Although projections indicate a decreasing trend, health inequalities have intensified. …”

Data Sheet 3_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf by Ying Liu (18461)

“…</p>Conclusion<p>Although projections indicate a decreasing trend, health inequalities have intensified. …”

Data Sheet 4_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf by Ying Liu (18461)

“…</p>Conclusion<p>Although projections indicate a decreasing trend, health inequalities have intensified. …”

Data Sheet 1_Low-dose cyclophosphamide combined with chinese herbal medicine Shuli Fenxiao formula for the treatment of intermediate-to-high risk primary membranous nephropathy.pdf by Yiran Du (12754172)

“…At 24 weeks of treatment, 61.3% of patients achieved partial response and 24.5% achieved complete response. All Anti-phosholipase A2 Receptor Antibody (Anti-PLA2R) seropositive patients achieved immune remission. 24-hour urine total protein quantification (24hUTP) decreased from a median of 6.1 (IQR, 4.6-8.4) g/d to 2.7 (IQR, 0.6-8.7) g/d (P<0.001). …”

Data_Sheet_1_Regional catastrophic health expenditure and health inequality in China.PDF by Yan Guo (83742)

“…</p>Methods<p>Using data from China's Household Panel Study (CFPS), we selected Shanghai, Henan and Gansu as representative eastern-central-western regional provinces to construct a unique 5-year CHE unbalanced panel dataset. CHE incidence was measured by calculating headcount; CHE intensity was measured by overshoot and CHE inequality was estimated by concentration curves (CC) and the concentration index (CI). …”

Table_1_Hydrolyzed Fat Formula Increases Brain White Matter in Small for Gestational Age and Appropriate for Gestational Age Neonatal Piglets.DOCX by Megan P. Caputo (8439465)

“…</p><p>Methods: Sex-matched, littermate pairs of SGA (0.5–0.9 kg) and AGA (1.2–1.8 kg) 2 days old piglets (N = 60) were randomly assigned to control (CON) or HF formula diets in a 2 × 2 factorial design. …”

Data Sheet 6_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf by Ying Liu (18461)

“…</p>Conclusion<p>Although projections indicate a decreasing trend, health inequalities have intensified. …”