Table_2_Characteristic of Perineural Invasion in Hilar Cholangiocarcinoma Based on Whole-Mount Histologic Large Sections of Liver.docx by Si-Yuan Wang (6307619)

“…Extrahepatic and intrahepatic PNI were identified in 20 (100%) patients and 1 (5.0%) patient, respectively. Vessel density decreased in most invaded nerves presented by CD-34, which correlated with 100% of poorly differentiated and 83% of moderately differentiated tumors (P<0.008).…”

Image_3_Modulation of Motor Cortex Activity After Intrathecal Baclofen Delivery in Chronic Thoracic Spinal Cord Injury.TIFF by Ivana Štětkářová (12540235)

“…</p>Methods<p>Ten subjects (eight males, 20–69 years) with thoracic SCI presenting no voluntary movements of lower limbs (except one) were enrolled in the fMRI study. fMRI at 1.5T with a finger tapping paradigm and mental movement simulating foot flexion on the dominant side were performed before, 3 months, and 1 year after start of cITBa. fMRI data processing was carried out using FMRI Expert Analysis Tool (FEAT), part of FSL. …”

DataSheet_1_Simulation of coastal resource and environmental carrying capacity in the Yangtze River delta coastal zone based on shared socioeconomic pathways.docx by Rongjuan Liu (7133834)

“…The carrying capacity under the five SSP scenarios did not improve. The mismatch between natural ecological conditions and the intensity of human activities in the shoreline area was more prominent than in the study area, with the SSP1 and SSP5 scenarios being the most obvious. …”

Essential Role of Neuron-Enriched Diacylglycerol Kinase (DGK), DGKβ in Neurite Spine Formation, Contributing to Cognitive Function by Yasuhito Shirai (239582)

“…In addition, overexpression of DGKβ in SH-SY5Y cells or primary cultured mouse hippocampal neurons resulted in branch- and spine-formation, while a splice variant form of DGKβ, which has kinase activity but loses membrane localization, did not induce branches and spines. …”

CYTOKININ AND AUXIN INFLUENCE ON GROWTH AND QUALITY OF WATERMELON IRRIGATED WITH SALINE WATER by GISELE LOPES DOS SANTOS (13289173)

“…The 25/75% (CPPU/IAA) proportion favored smaller decreases in leaf area and total dry mass under a saline condition of 2.0 dS m−1. …”

table1_Danggui-Shaoyao-San (DSS) Ameliorates Cerebral Ischemia-Reperfusion Injury via Activating SIRT1 Signaling and Inhibiting NADPH Oxidases.docx by Yunxia Luo (6661694)

“…We found that 1) ethanol extract of DSS, instead of aqueous extract, reduced infarct sizes and improved neurological deficit scores in the post-ischemic stroke rats; 2) Ethanol extract of DSS down-regulated the expression of the cleaved-caspase 3 and Bax, up-regulated bcl-2 and attenuated apoptotic cell death in the ischemic brains; 3) Ethanol extract of DSS decreased the production of superoxide and peroxynitrite; 4) Ethanol extract of DSS significantly down-regulated the expression of p67^phox but has no effect on p47^phox and iNOS statistically. 5) Ethanol extract of DSS significantly up-regulated the expression of SIRT1 in the cortex and striatum of the post-ischemic brains; 6) Co-treatment of EX527, a SIRT1 inhibitor, abolished the DSS’s neuroprotective effects. …”

Table_3_Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids.xls by Qian Zhuang (621842)

“…GPs increased the hepatic expression of genes encoding the cytochrome P450 (Cyp) enzymes Cyp7a1, Cyp7b1, and Cyp8b1, while decreasing the hepatic expression of genes encoding the adenosine triphosphate-binding cassette (Abc) transporters Abcg5 and Abcg8. …”

Polarity-Induced Reactive Wetting: Spreading and Retracting Sessile Water Drops by William S. Y. Wong (2795890)

“…Drops contacting the transition spread before retracting, occurring over the time scale of a few seconds. This phenomenon contradicts current understanding, exhibiting a uniquely (1) decreasing advancing contact angle and (2) increasing receding contact angle. …”

Data_Sheet_1_Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors.PDF by Diane L. Rosin (13165353)

“…Ilofotase alfa rescued CD73^–/– mice, which lack a 5′-ectonucleotidase that dephosphorylates AMP to adenosine; ZM241,385 inhibited that protection. …”

Evidence for home advantage in the time intervals between scores. by Haroldo V. Ribeiro (277883)

“…Here we have aggregated data from all seasons (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152440#pone.0152440.s004" target="_blank">S3</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152440#pone.0152440.s005" target="_blank">S4</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152440#pone.0152440.s006" target="_blank">S5</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152440#pone.0152440.s007" target="_blank">S6</a> Figs for individual results). …”

Kisspeptin expression by human term placenta. by Zahra Rasoulzadeh (2622283)

“…With purified Kp-10, anti-Kp-54/Kp-145 produced a single band at about 1.5 kDa, which is in good agreement with the theoretical MW for Kp-10-13. β-actin served as loading control. …”

Identification of SNP loci and candidate genes related to four important fatty acid composition in <i>Brassica napus</i> using genome wide association study by Qianglong Zhu (3614309)

“…<i>FAE1</i> and <i>BnaC</i>. <i>FAE1</i> on the A08 and C03 chromosomes, and other potential candidate genes involving in the fatty acid biosynthesis pathway, such as the orthologs genes of <i>FAD2</i>, <i>LACS09</i>, <i>KCS17</i>, <i>CER4</i>, <i>TT16</i> and <i>ACBP5</i>. …”

One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease - Fig 3 by Behzad Najafian (299389)

“…However, occasional podocytes showed no GL3 inclusions (Ø); <b>(C)</b>Total volume of GL3 inclusions per podocytes V(Inc/PC) was reduced after 11–12 months of ERT (p = 0.02); <b>(D)</b> Podocyte GL3 score (semiquantitative [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152812#pone.0152812.ref014" target="_blank">14</a>]) did not reduce significantly after 11–12 months (follow-up) of ERT (p = 0.18); <b>(E)</b> Podocyte volume significantly decreased after 11–12 months of ERT compared to baseline (p = 0.02). …”

Rate of ATP consumption by tumor cells can modulate the preference for aerobic glycolysis versus oxidative phosphorylation. by Shubham Tripathi (5479454)

“…The behavior shown is representative of that reported by te Boekhorst <i>et al</i>. [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009841#pcbi.1009841.ref035" target="_blank">35</a>] (see <i>Fig 5E</i> therein). …”

DataSheet1_Case report: further delineation of AEBP1-related Ehlers–Danlos Syndrome (classical-like EDS type 2) in an additional patient and comprehensive clinical and molecular re... by Tomomi Yamaguchi (6843290)

“…A next-generation sequencing panel-based analysis revealed compound heterozygous variants in AEBP1: NM_001129.5:c.[2296G>T]; [2383dup], p.…”

Data_Sheet_1_Interaction of energy and sulfur microbial diet and smoking status with polygenic variants associated with lipoprotein metabolism.PDF by Haeng Jeon Hur (6808157)

“…The risk alleles of CETP_rs708272 and ALDH1A2_rs588136 were linked to increased expression in the heart and decreased in the brain, respectively. …”

Data Sheet 2_Bevacizumab and anlotinib combination therapy acts via HIF-1α suppression to exert synergistic anti-angiogenic and anti-tumor effects in non-small cell lung cancer.pdf... by Nafeisha Simayi (22262161)

“…B+A inhibited cell viability by 78%, colony formation by 90%, and invasion by 75% in NSCLC cell lines A549 and H1299; downregulated N-cadherin 5.34-fold, vimentin 6.46-fold, and α-SMA 4.35-fold; and upregulated E-cadherin 3.75-fold. …”

Nano-ciprofloxacin/meropenem exhibit bactericidal activity against Gram-negative bacteria and rescue septic rat model supplementary data by Safy Hadiya (9463872)

“…Synergy was evidenced for CS<b>/</b>Plu-Cip<b>/</b>Mer with a bactericidal effect (at 1<b>× </b>MIC and sub-MICs), and it significantly decreased bacterial load and rescued infected rats. …”

Data Sheet 1_Bevacizumab and anlotinib combination therapy acts via HIF-1α suppression to exert synergistic anti-angiogenic and anti-tumor effects in non-small cell lung cancer.zip... by Nafeisha Simayi (22262161)

“…B+A inhibited cell viability by 78%, colony formation by 90%, and invasion by 75% in NSCLC cell lines A549 and H1299; downregulated N-cadherin 5.34-fold, vimentin 6.46-fold, and α-SMA 4.35-fold; and upregulated E-cadherin 3.75-fold. …”

Data_Sheet_1_MiR-223-3p Alleviates Vascular Endothelial Injury by Targeting IL6ST in Kawasaki Disease.pdf by Xiang Wang (127867)

“…The values of IL-6, E-selectin, and ICAM-1 mRNA expressions decreased, while the value of IL-6ST was increased between the agonist treated mice and KD mice. …”