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100781
Fetal Alcohol Exposure Reduces Dopamine Receptor D2 and Increases Pituitary Weight and Prolactin Production via Epigenetic Mechanisms
Published 2015“…Also, they show elevated pituitary mRNA levels of DNA methylating genes (DNMT1, DNMT3b, MeCP2) and histone modifying genes (HDAC2, HDAC4, G9a). When fetal alcohol exposed rats were treated neonatally with a DNA methylation inhibitor 5-Aza deoxycytidine and/or a HDAC inhibitor trichostatin-A their pituitary D2R mRNA, pituitary weights and plasma PRL levels were normalized. …”
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100782
Table_1_SHROOM4 Variants Are Associated With X-Linked Epilepsy With Features of Generalized Seizures or Generalized Discharges.DOCX
Published 2022“…</p>Results<p>Six hemizygous missense SHROOM4 variants, including c.13C > A/p. Pro5Thr, c.3236C > T/p.Glu1079Ala, c.3581C > T/p.Ser1194Leu, c.4288C > T/p.Arg1430Cys, c.4303G > A/p.Val1435Met, c.4331C > T/p.Pro1444Leu, were identified in six cases with idiopathic epilepsy without intellectual disability. …”
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100783
Table_1_Nitrogen-Induced Changes in Soil Environmental Factors Are More Important Than Nitrification and Denitrification Gene Abundance in Regulating N2O Emissions in Subtropical F...
Published 2022“…Therefore, a <sup>15</sup>N-tracing laboratory experiment with four N application rates (0, 12.5, 25, and 50 μg <sup>15</sup>N g<sup>–1</sup> soil) was conducted to investigate the response of nitrification- and denitrification-derived N<sub>2</sub>O to N additions in an evergreen broad-leaved forest (BF) and a Pinus forest (PF) in the Wuyi Mountains in southeastern China. …”
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100784
The tempo and mode of the taxonomic correction process: How taxonomists have corrected and recorrected North American bird species over the last 127 years
Published 2018“…Since North American bird species are known to have been extensively lumped in the first half of the 20<sup>th</sup> century with the advent of the biological species concept, we determined whether most splits seen today were the result of those lumps being recorrected. We found that 5% of lumps and 23% of splits fully reverted previous corrections, while a further 3% of lumps and 13% of splits are partial reversions. …”
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100785
Pearson correlation coefficients (k): SLGC markers.
Published 2024“…–For abbreviations, see the legends to Figs <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0291368#pone.0291368.g005" target="_blank">5</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0291368#pone.0291368.g006" target="_blank">6</a>.…”
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100786
TPL2 activation in ADI prostate cancer of the <i>Pten</i> deletion mouse model.
Published 2011“…(D) MTT assays to measure cell proliferation of E cells (E2 and E4) and CE cells (CE1 and CE3) with the treatment of different levels of TPL2 inhibitor (0, 1, 5, or 10 µM). Statistically significant decreases in cell proliferation in comparison to vehicle treatment are marked with * (p<0.05).…”
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100787
Data_Sheet_1_Saccharification Potential of Transgenic Greenhouse- and Field-Grown Aspen Engineered for Reduced Xylan Acetylation.xlsx
Published 2021“…<p>High acetylation of xylan in hardwoods decreases their value as biorefinery feedstocks. To counter this problem, we have constitutively suppressed RWA genes encoding acetyl-CoA transporters using the 35S promoter, or constitutively and wood-specifically (using the WP promoter) expressed fungal acetyl xylan esterases of families CE1 (AnAXE1) and CE5 (HjAXE), to reduce acetylation in hybrid aspen. …”
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100788
Pharmacokinetic Compatibility of Ginsenosides and <i>Schisandra</i> Lignans in <i>Shengmai-san</i>: From the Perspective of P-Glycoprotein
Published 2014“…</p><p>Results and Conclusions</p><p>The efflux ratios of ginsenoside Rb2, Rc, Rg2, Rg3, Rd and Rb1 were found more than 3.5 in L-MDR1 cells and can be decreased significantly by verapamil (a classical P-gp inhibitor). …”
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100789
Presentation_1_Molecular Surveillance and Ex Vivo Drug Susceptibilities of Plasmodium vivax Isolates From the China–Myanmar Border.pptx
Published 2021“…<p>Drug resistance in Plasmodium vivax may pose a challenge to malaria elimination. Previous studies have found that P. vivax has a decreased sensitivity to antimalarial drugs in some areas of the Greater Mekong Sub-region. …”
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100790
Mutation of acetylated lysine residues results in mislocalization of NDPK-D.
Published 2015“…Acetylation levels were determined as described in (A). Replacement of lysine residues with arginine decreased acetylation levels. n = 3. …”
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100791
Image_1_Molecular Serotype-Specific Identification of Non-type b Haemophilus influenzae by Loop-Mediated Isothermal Amplification.PDF
Published 2022“…To address this issue, we developed a rapid, simple, and cost-effective method for detecting serotypes of H. influenzae. …”
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100792
Table_1_Molecular Serotype-Specific Identification of Non-type b Haemophilus influenzae by Loop-Mediated Isothermal Amplification.DOCX
Published 2022“…To address this issue, we developed a rapid, simple, and cost-effective method for detecting serotypes of H. influenzae. …”
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100793
<i>CENPE</i> expression is associated with its DNA methylation status in esophageal adenocarcinoma and independently predicts unfavorable overall survival
Published 2019“…Univariate and multivariate analysis confirmed that <i>CENPE</i> expression was an independent indicator of unfavorable OS in EA patients, as a continuous variable (HR: 1.861, 95%CI: 1.235–2.806, <i>p</i> = 0.003) or as categorical variables (HR: 2.550, 95%CI: 1.294–5.025, <i>p</i> = 0.007). …”
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100794
Data Sheet 1_Past and future trends in swiss snow cover: multi-decades analysis using the snow observation from space algorithm.docx
Published 2025“…The pixel-wise analysis reveals significant negative trends in the monthly NDSI across all seasons, with the most pronounced decreases at low to mid-elevations, particularly in winter and spring (e.g., a 50% reduction in NDSI for pixels showing positive significative trends in winter below 1,000 m, and a 43% reduction in spring between 1,000 and 2,000 m). …”
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100795
Image_1_Molecular Serotype-Specific Identification of Non-type b Haemophilus influenzae by Loop-Mediated Isothermal Amplification.PDF
Published 2022“…To address this issue, we developed a rapid, simple, and cost-effective method for detecting serotypes of H. influenzae. …”
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100796
Observed SSTI incidence rate and counterfactuals.
Published 2024“…SCS had no effect on the average length of hospitalizations, but there was a decreasing post-intervention trend in hospitalizations involving surgery (-0.03; 95% CI: -0.06, 0.00).…”
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100797
Table_1_Molecular Serotype-Specific Identification of Non-type b Haemophilus influenzae by Loop-Mediated Isothermal Amplification.DOCX
Published 2022“…To address this issue, we developed a rapid, simple, and cost-effective method for detecting serotypes of H. influenzae. …”
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100798
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100799
Supplementary file 1_Past and future trends in swiss snow cover: multi-decades analysis using the snow observation from space algorithm.docx
Published 2025“…The pixel-wise analysis reveals significant negative trends in the monthly NDSI across all seasons, with the most pronounced decreases at low to mid-elevations, particularly in winter and spring (e.g., a 50% reduction in NDSI for pixels showing positive significative trends in winter below 1,000 m, and a 43% reduction in spring between 1,000 and 2,000 m). …”
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100800
Table1_Novel Insight Into the Role of ACSL1 Gene in Milk Production Traits in Buffalo.docx
Published 2022“…<p>Understanding the genetic mechanisms underlying milk production traits contribute to improving the production potential of dairy animals. Long-chain acyl-CoA synthetase 1 (ACSL1) plays a key role in fatty acid metabolism and was highly expressed in the lactating mammary gland epithelial cells (MGECs). …”