Model simulations reproduce Toll-dependent and Toll independent pathway mutant conditions. by Claudio D. T. Barros (10885464)

“…(G-L) Simulations increasing kinetic constant k9 (G-I) or k5 (J-L), by 3x, 2x or 1.5x, in a <i>cact</i>^<i>A2</i>/<i>cact</i>^<i>011</i> mutant background. …”

DNA binding activity of RegX3. by Gretta Roberts (217668)

“…<p>(A) Phosphorylation of RegX3 by EnvZ. 1 µM EnvZ protein was incubated with ³²P-ATP for 5 min. …”

Isoflurane reduces endothelial cell apoptosis and inflammation via CD73. by Mihwa Kim (580181)

“…In contrast, EA.hy926 cells treated with 2.5% isoflurane for 1 hr before the induction of apoptosis isoflurane showed reduced apoptotic death indicated by decreased PARP and caspase-3 fragmentation. …”

Comparison of limiting logistic distribution for hitting times with stochastic simulations. by Michael D. Nicholson (6589175)

“…Birth/death parameters: A (net growth rate decreases then increases), <i>α</i>₁ = <i>α</i>₂ = 1, <i>α</i>₃ = 1.4, <i>β</i>₁ = <i>β</i>₃ = 0.3, <i>β</i>₂ = 1.5; B, D (net growth rate increases then decreases); <i>α</i>₁ = <i>α</i>₃ = 1, <i>α</i>₂ = 1.4, <i>β</i>₁ = <i>β</i>₂ = 0.3, <i>β</i>₃ = 1.5; C (neutral), <i>α</i>₁ = <i>α</i>₂ = <i>α</i>₃ = 1, <i>β</i>₁ = <i>β</i>₂ = <i>β</i>₃ = 0.3. …”

Sex Differences in β-Adrenergic Responsiveness of Action Potentials and Intracellular Calcium Handling in Isolated Rabbit Hearts by Gregory S. Hoeker (650231)

“…These sex differences were more significant at faster (5.5 Hz) than resting rates (3 Hz). Treatment with Iso led to the development of spontaneous calcium release (SCR) with a dose threshold of 31.6 nM. …”

Allele Distributions under Environmental Fluctuations by Lauren Ancel Meyers (27605)

“…As environmental variability decreases, the population moves from the intermediate phenotype to the genetic boundary between the A and B phenotypes, and eventually to an oscillation between the center of the network for A and the gene for B. …”

Data_Sheet_1_Bioinformatic and functional characterization of cyclic-di-GMP metabolic proteins in Vibrio alginolyticus unveils key diguanylate cyclases controlling multiple biofilm... by Xiao-Xiao Gong (17018958)

“…This work provides a robust foundation for the study of the molecular mechanisms of c-di-GMP in the biofilm formation of V. alginolyticus.…”

Virulent leptospires become mammalian host-adapted during growth within dialysis membrane chambers. by Melissa J. Caimano (183705)

“…<p>Representative whole cell lysates of leptospires cultivated to late-logarithmic phase in EMJH medium at 30°C <i>in vitro</i> (IV) and within dialysis membrane chambers (DMC) implanted into the peritoneal cavities of female Sprague-Dawley rats. (A) Lysates were loaded according to the numbers of leptospires (5×10⁶ per lane) or total protein (5 µg per lane) and stained with SYPRO Ruby gel stain. …”

Data_Sheet_1_Correlation between retinal structure and brain multimodal magnetic resonance imaging in patients with Alzheimer’s disease.docx by Xiaoli Hao (2156446)

“…</p>Conclusion<p>Our study demonstrated that retinal structure change was related to the loss of integrity of white matter fiber tracts in the visual pathway and the decreased LGN volume and functional metabolism of V1 in AD patients. …”

Image_1_Hereditary Xerocytosis: Differential Behavior of PIEZO1 Mutations in the N-Terminal Extracellular Domain Between Red Blood Cells and HEK Cells.JPEG by Yohei Yamaguchi (716799)

“…How these PIEZO1 mutations impair channel function and alter red blood cell (RBC) physiology, is not completely understood. Here, we report the characterization of mutations in the N-terminal part of the protein (V598M, F681S and the double mutation G782S/R808Q), a part of the channel that was subject of many investigations to decipher its role in channel gating. …”

Image_1_Hereditary Xerocytosis: Differential Behavior of PIEZO1 Mutations in the N-Terminal Extracellular Domain Between Red Blood Cells and HEK Cells.JPEG by Yohei Yamaguchi (716799)

“…How these PIEZO1 mutations impair channel function and alter red blood cell (RBC) physiology, is not completely understood. Here, we report the characterization of mutations in the N-terminal part of the protein (V598M, F681S and the double mutation G782S/R808Q), a part of the channel that was subject of many investigations to decipher its role in channel gating. …”

Image_2_Hereditary Xerocytosis: Differential Behavior of PIEZO1 Mutations in the N-Terminal Extracellular Domain Between Red Blood Cells and HEK Cells.JPEG by Yohei Yamaguchi (716799)

“…How these PIEZO1 mutations impair channel function and alter red blood cell (RBC) physiology, is not completely understood. Here, we report the characterization of mutations in the N-terminal part of the protein (V598M, F681S and the double mutation G782S/R808Q), a part of the channel that was subject of many investigations to decipher its role in channel gating. …”

Image_2_Hereditary Xerocytosis: Differential Behavior of PIEZO1 Mutations in the N-Terminal Extracellular Domain Between Red Blood Cells and HEK Cells.JPEG by Yohei Yamaguchi (716799)

“…How these PIEZO1 mutations impair channel function and alter red blood cell (RBC) physiology, is not completely understood. Here, we report the characterization of mutations in the N-terminal part of the protein (V598M, F681S and the double mutation G782S/R808Q), a part of the channel that was subject of many investigations to decipher its role in channel gating. …”

Assessing worst case scenarios in movement demands derived from global positioning systems during international rugby union matches: Rolling averages versus fixed length epochs by Daniel J. Cunningham (3337278)

“…<div><p>The assessment of competitive movement demands in team sports has traditionally relied upon global positioning system (GPS) analyses presented as fixed-time epochs (e.g., 5–40 min). More recently, presenting game data as a rolling average has become prevalent due to concerns over a loss of sampling resolution associated with the windowing of data over fixed periods. …”

Change rate (μg g^-1 day^-1) in different DOC molecular-size pools during the incubation (Eq 1). by Ari Laurén (7484720)

“…<p>Parameter γ represents the change rate for mor (S_m), no worms (W₀), lower moisture status (θ₁) at 5°C temperature (T₅). The other treatment effects and the interaction effects (from W₁ to T₂₀ & S_p) are expressed as a difference with respect to γ. …”

Relative expression of Paneth cell AMPs correlates with severity of acute GI GvHD. by Daniela Weber (3470189)

“…<p>In the small intestine the relative expression of HD5 (p = 0.004), HD6 (p = 0.006) and Reg3α (p = 0.012) was significantly decreased (Mann-Whitney-U-Test) in case of severe acute GvHD (stage 2–4) (3A). …”

Stratification of genes that were differentially expressed in tissues determined to be infected (WNV (+)) or uninfected (WNV (−)) based on sensitive qRT-PCR detection of WNV RNA. by José Peña (95514)

Impact of 3-Amino-1,2,4-Triazole (3-AT)-Derived Increase in Hydrogen Peroxide Levels on Inflammation and Metabolism in Human Differentiated Adipocytes by Francisco Javier Ruiz-Ojeda (3214866)

“…Excessive H₂O₂ levels are degraded by catalase (CAT), the activity of which is decreased in obesity. We investigated the effects of inhibition of catalase activity on metabolism and inflammation by incubating human differentiated adipocytes with 10 mM 3-amino-1,2,4-triazole (3-AT) for 24 h. …”

Table_1_The global burden of cardiovascular disease attributable to diet high in sugar-sweetened beverages among people aged 60 years and older: an analysis for the global burden o... by Jiajie Lv (19179028)

“…ASMR declined from 19.5 to 13 per 100,000 (estimated annual percentage change (EAPC): −1.46%) and ASDR declined from 345.8 to 220.6 per 100,000 (EAPC: −1.66%). …”

New draft item by Helen Musulan (3119433)

“…Having a height requirement decreased the probability of counting a non-woody plant. …”