Image_3_QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice.TIF by Xiangming Wang (372213)

“…It was also found that the expression of SIRT1 and the proportion of p-AMPK (thr172)/AMPK were increased, while the p-mTOR (ser2448)/mTOR ratio was decreased after QDTS treatment in db/db mice, which was consistent with the effect of its active ingredients on the nutrient-sensing signal pathway as reported previously. …”

Table_1_QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice.DOCX by Xiangming Wang (372213)

“…It was also found that the expression of SIRT1 and the proportion of p-AMPK (thr172)/AMPK were increased, while the p-mTOR (ser2448)/mTOR ratio was decreased after QDTS treatment in db/db mice, which was consistent with the effect of its active ingredients on the nutrient-sensing signal pathway as reported previously. …”

Image_1_QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice.TIF by Xiangming Wang (372213)

“…It was also found that the expression of SIRT1 and the proportion of p-AMPK (thr172)/AMPK were increased, while the p-mTOR (ser2448)/mTOR ratio was decreased after QDTS treatment in db/db mice, which was consistent with the effect of its active ingredients on the nutrient-sensing signal pathway as reported previously. …”

Image_2_QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice.TIF by Xiangming Wang (372213)

“…It was also found that the expression of SIRT1 and the proportion of p-AMPK (thr172)/AMPK were increased, while the p-mTOR (ser2448)/mTOR ratio was decreased after QDTS treatment in db/db mice, which was consistent with the effect of its active ingredients on the nutrient-sensing signal pathway as reported previously. …”

Specificity of the dAtx2/ Ataxin-1 Interaction by Ismael Al-Ramahi (85012)

Table_1_Effect of the Tea Tree Oil on Growth Performance, Meat Quality, Serum Biochemical Indices, and Antioxidant Capacity in Finishing Pigs.DOCX by Tianyu Yang (3527117)

“…The TTO supplementation increased (P < 0.05) C18:2n6t concentration and decreased (P < 0.05) C12:0 and C16:0 concentration, relative to the control group. …”

Genome-wide characterization of LTF-responsive viral TSRs. by Ming Li (91180)

“…<p>(<b>A and B</b>) HFF infected with HCMV TB40/E UL79^HF (A) or Towne UL87^HF (B) for 72 or 96 h, respectively, were treated with dTag2 or dTag1 for the last 6 h of infection. …”

PINK1 auto-phosphorylation is impaired by L347P and E417G mutations. by Wencheng Liu (374270)

“…Lysates from the SH-SY5Y cells expressing wild type-PINK1-Flag (1^st and 2^nd panels), L347P-PINK1-Flag (3^rd and 4^th panels) or E417G- PINK1-Flag (5^th and 6^th panels) were subjected to 2-dimensional gel electrophoresis, followed by Western analyses using anti-Flag Ab. …”

An analysis of drug recognition expert evaluations and comparisons with police issued citations in Maryland, 2017–2021 by Komal Bhagat (21376985)

“…DRE accuracy improved to 91.8 ± 0.85% when none or one drug was detected and decreased to 80.5 ± 0.87% when two or more drugs were involved. …”

Analysis of pulmonary microecology and clinical characteristics of patients carrying human herpesvirus by Jing Luo (146659)

Data_Sheet_1_Differential Variation in Non-structural Carbohydrates in Root Branch Orders of Fraxinus mandshurica Rupr. Seedlings Across Different Drought Intensities and Soil Subs... by Li Ji (796082)

“…With increasing root order, the explanation of the variation in root traits by ST decreased (only 6.8% for 5th-order roots). The observed response in terms of morphological traits of different fine root branch orders of F. mandshurica seedlings to resource fluctuations ensures the maintenance of a low cost-benefit ratio in the root system development.…”

The pattern of proliferation along the heart tube is dynamic and is regulated by Tbx3 and Tbx2. by Inês Ribeiro (25630)

“…(H) Histogram showing the average of the total number of BrdU positive cells in the heart of 33 hpf embryos: wt, 31.4±1.661 (n = 5); Tbx3 mRNA, 17.5±1.708 (p<0.001; n = 6); Tbx2 mRNA, 17.0±1.000 (p<0.001; n = 7); <i>tbx3b</i> MO, 28.0±0.408 (n = 4); tbx2a MO, 31.3±2.658 (n = 4); double MO, 36.8±1.797 (n = 4). a, atrium; h, heart; nt, neural tube; v, ventricle.…”

Purkinje cell degeneration in TRAF4-KO cerebellum. by Sébastien Blaise (332585)

“…<p>(A): analyses of WT (a, c, e and g) and TRAF4-KO (b, d, f and h) cerebellum at 15 postnatal days; (a, b) cresyl violet staining of parasagittal sections (ML, molecular layer; GL, granular cell layer; WM, white matter); (c, d) white matter immunofluorescence analysis of calb28 (green); In the absence of TRAF4, the number of Purkinje cells was decreased. …”

Ruminal and morphometric parameters of rumen and intestine in lambs fed guava (Psidium guajava L.) agroindustrial waste by Priscila Torres Nobre (7529792)

“…There was a quadratic effect for papilla width, with a maximum value of 393.33 μm at the level of 34.43% GAW in the diet. …”

Effectiveness of EDTA in restorative procedures with self-etching adhesives by Camila Cruz LORENZETTI (6148994)

“…<p></p><p>Abstract Introduction Self-etching adhesives have simplified adhesive technique and decreased the postoperative sensitivity. When applied on dentin, it acts on the smear layer, but it is still a challenge in the effectiveness of this removal. …”

Mapping of the minimal functional region of the Notch1 promoter in primary human keratinocytes versus HeLa cells. by Chiara Lambertini (249675)

“…<p>(A) Different fragments of the human Notch1 promoter with decreasing 5′ ends were cloned into a luciferase reporter plasmid, followed by transient transfection into primary human keratinocytes and HeLa cells (black and grey bars, respectively) together with a Renilla minimal reporter for normalization. …”

Estrogen receptors in the VTA acutely regulate the sensitivity of DA neurons to ethanol but not DA. by Bertha J. Vandegrift (4573780)

“…<p>(A-B) Representative rate meter graphs showing response to 5 μM DA of a VTA DA neuron from a mouse in estrus (A) or diestrus (B) recorded before and during treatment with ICI 182,780. …”

miR-335-3p targeting THBS1 is downregulated in the fibrosis model. by Dong-Hee Han (140305)

“…<p>Transcriptome analysis on miRNA was conducted after treatment with 1 and 5 ng/mL TGF-β1 for 48 h. <b>(A)</b> miRNAs with significantly changed expression following TGF-β1 treatment were identified for each cell type. …”

datasheet1_Mitochondrial Function, Fatty Acid Metabolism, and Body Composition in the Hyperbilirubinemic Gunn Rat.pdf by Josif Vidimce (7903265)

“…<p>Background: Circulating bilirubin is associated with reduced adiposity in human and animal studies. A possible explanation is provided by in vitro data that demonstrates that bilirubin inhibits mitochondrial function and decreases efficient energy production. …”

Data_Sheet_1_The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes.PDF by Balázs Ördög (3342644)

“…The concomitant membrane potential (V_m) responses also showed a ChR variant-specific profile, with GtACR1 causing a slight increase in average V_m during illumination (V_plateau: −38 mV) as compared with a V_plateau > −20 mV for the other ChR variants. …”