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461
Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis
Published 2019“…Background When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. …”
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462
Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey.
Published 2020“…The association between egg consumption and diabetes is inconclusive. We aimed to examine the association between long-term egg consumption and its trajectory with diabetes in Chinese adults. …”
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463
Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation
Published 2016“…Municipal solid waste management is one of the major challenges facing Qatar with more than 2.5 million tons of municipal solid waste each year, a very high waste generation rate in a country with small land mass. …”
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464
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465
Dynamic Imaging of Hydrate Specific Area Evolution during Xenon Hydrate Formation
Published 2020“…During hydrate formation and dissociation, full 3D images are acquired at a time resolution of 45 seconds and a spatial resolution of 5.38 ?…”
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466
Electrocatalytic arsenite oxidation in bicarbonate solutions combined with CO2 reduction to formate
Published 2020“…However, the application of a potential higher than the peak (E > Ep,As) leads to a significant decrease in the FE due to water oxidation. …”
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467
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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468
Smoking cessation counseling in Qatar: Community pharmacists' attitudes, role perceptions and practices
Published 2012“…Main outcome measures: Qatar community pharmacists' smoking cessation practices, their attitudes toward tobacco use, smoking cessation and smoking cessation counseling and their perceived barriers for smoking cessation counseling. Results: Over 5 months, we collected 127 surveys (40 % response rate). …”
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469
Effects of financial turmoil on financial integration and risk premia in emerging markets
Published 2016“…Our sample consists of monthly data for 12 emerging stock markets over the period 1988M3-2015M3. …”
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470
The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments
Published 2004“…The mean hole volume, vh, varies in PS between 105 Å3 (27 °C) and 220 Å3 (190 °C), and shows a systematic decrease with increasing AN content, at Tg from 121 Å3 for PS to 102 (±2) Å3 for SAN50. …”
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471
Cold Plasma as Effective Tool for Aluminum Surface Cleaning
Published 2016“…In the final step, two layers of foils are wounded together and rolling oil is sprayed between the two layers and the -twin foil- is rolled down. A continuous amorphous oxide layer is formed immediately after rolling process due to the reaction of oxygen and air humidity and therefore new metal surface is produced [5]. …”
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472
Origanum Syriacum Inhibits Proliferation, Migration, Invasion and Induces Differentiation of Human Aortic Smooth Muscle Cells
Published 2014“…Cardiovascular diseases (CVDs) are still the number one cause of morbidity and mortality both in Qatar and worldwide. A major risk factor of CVDs is atherosclerosis, the hardening of blood vessels caused by decreased diameter and formation of plaque. …”
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473
Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse
Published 2016“…The three compounds could inhibit AR activity up to 90 % at 12.5 μM of phloretin, EGCG and [6]-gingerol with IC50 values of 4.1 μM, 3.7 μM, and 2.4 μM, respectively. …”
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474
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475
Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries
Published 2022“…Consumption of ketoconazole slowly declined, with 5.04% annual decrease, probably due to labelling changes in 2013 to reflect hepatotoxicity concerns. …”
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476
Empower Generations: Longitudinal Study for National Capacities in Life Sciences and Healthcare
Published 2021“…However, the association between a history of EG training and the university’s GPA is significant, with a p < 0.001, OR 5.016 (2.954–8.518). …”
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477
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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478
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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479
Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate
Published 2020“…Herein we report a catalyst consisting of CuAg/Cu2O nanoparticles (NPs), synthesized on the two-dimensional carbon nitride (CN) surface via galvanic exchange route for electrocatalytic methanol oxidation and carbon dioxide reduction. …”
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480
EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS
Published 2016“…The expression of Adhesion proteins (ICAM-1 and E-selectin) were increased in hyperglycemia and decreased expression with PBA. Conclusion: Our results suggest that hyperglycemia may activate ER stress that could play a role in the angiogenesis in the diabetic retinopathy.…”
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