Image_2_Oral Delivered Dexmedetomidine Promotes and Consolidates Non-rapid Eye Movement Sleep via Sleep–Wake Regulation Systems in Mice.TIF by Zhen-Xin Feng (6050156)

“…Unlike the classic hypnotic diazepam, dexmedetomidine also increased the delta power in the EEG spectra of NREM sleep, especially at the frequency of 1.75–3.25 Hz, while ranges of 0.5–1.0 Hz were decreased. Immunohistochemical analysis showed that orally delivered dexmedetomidine 100 μg/kg at 2 h into the dark cycle decreased c-Fos expression in the cerebral cortex and sub-cortical arousal systems, while it increased c-Fos expression in the neurons of the ventrolateral preoptic nucleus. …”

Upregulation of miR21 and Repression of Grhl3 by Leptin Mediates Sinusoidal Endothelial Injury in Experimental Nonalcoholic Steatohepatitis by Sahar Pourhoseini (690459)

“…Using rodent models of NASH, and transgenic mice lacking leptin and leptin receptor, results showed that hyperleptinemia caused a 4–5 fold upregulation of hepatic miR21 as assessed by qRTPCR. …”

Image_1_Oral Delivered Dexmedetomidine Promotes and Consolidates Non-rapid Eye Movement Sleep via Sleep–Wake Regulation Systems in Mice.TIF by Zhen-Xin Feng (6050156)

“…Unlike the classic hypnotic diazepam, dexmedetomidine also increased the delta power in the EEG spectra of NREM sleep, especially at the frequency of 1.75–3.25 Hz, while ranges of 0.5–1.0 Hz were decreased. Immunohistochemical analysis showed that orally delivered dexmedetomidine 100 μg/kg at 2 h into the dark cycle decreased c-Fos expression in the cerebral cortex and sub-cortical arousal systems, while it increased c-Fos expression in the neurons of the ventrolateral preoptic nucleus. …”

RNA-seq based expression profile of durian P450s. by Nithiwat Suntichaikamolkul (8193135)

“…<p>(A) Four tissues of Musangking cultivar. (B) Five ripening stages of Monthong cultivar. …”

table_1_Circulating and Adipose Tissue mRNA Levels of Zinc-α2-Glycoprotein, Leptin, High-Molecular-Weight Adiponectin, and Tumor Necrosis Factor-Alpha in Colorectal Cancer Patients... by Huijuan Zhu (668017)

“…Serum leptin levels in the OW/OB + CRC group were found to be increased by 57.7%, while HMW-ADPN levels were decreased by 23.5% when compared with the NW + CRC group of CRC patients. …”

image_2_Circulating and Adipose Tissue mRNA Levels of Zinc-α2-Glycoprotein, Leptin, High-Molecular-Weight Adiponectin, and Tumor Necrosis Factor-Alpha in Colorectal Cancer Patients... by Huijuan Zhu (668017)

“…Serum leptin levels in the OW/OB + CRC group were found to be increased by 57.7%, while HMW-ADPN levels were decreased by 23.5% when compared with the NW + CRC group of CRC patients. …”

table_2_Circulating and Adipose Tissue mRNA Levels of Zinc-α2-Glycoprotein, Leptin, High-Molecular-Weight Adiponectin, and Tumor Necrosis Factor-Alpha in Colorectal Cancer Patients... by Huijuan Zhu (668017)

“…Serum leptin levels in the OW/OB + CRC group were found to be increased by 57.7%, while HMW-ADPN levels were decreased by 23.5% when compared with the NW + CRC group of CRC patients. …”

image_1_Circulating and Adipose Tissue mRNA Levels of Zinc-α2-Glycoprotein, Leptin, High-Molecular-Weight Adiponectin, and Tumor Necrosis Factor-Alpha in Colorectal Cancer Patients... by Huijuan Zhu (668017)

“…Serum leptin levels in the OW/OB + CRC group were found to be increased by 57.7%, while HMW-ADPN levels were decreased by 23.5% when compared with the NW + CRC group of CRC patients. …”

Bicyclic α‑Iminophosphonates as High Affinity Imidazoline I₂ Receptor Ligands for Alzheimer’s Disease by Sònia Abás (3614849)

“…Acute treatment in mice with a selected compound significantly decreased Fas-associated protein with death domain (FADD) in the hippocampus, a key signaling mediator of neuroprotective actions. …”

DataSheet2_Surface Reactivity of Carbonaceous Nanoparticles: The Importance of Surface Pocket.ZIP by Hongyu Wang (366946)

“…The lowest barrier height of ∼8.5 kcal/mol is observed at a C-H site locating in a surface pocket. …”

DataSheet1_Surface Reactivity of Carbonaceous Nanoparticles: The Importance of Surface Pocket.ZIP by Hongyu Wang (366946)

“…The lowest barrier height of ∼8.5 kcal/mol is observed at a C-H site locating in a surface pocket. …”

DataSheet3_Surface Reactivity of Carbonaceous Nanoparticles: The Importance of Surface Pocket.docx by Hongyu Wang (366946)

“…The lowest barrier height of ∼8.5 kcal/mol is observed at a C-H site locating in a surface pocket. …”

Compensatory evolution at TSS-distal sequences. by Ephraim Kenigsberg (234366)

“…<p><b>A</b>) <b>The TSS-distal trinucleotide spectrum is modified.…”

Mechanism of fast calcium release triggered by RyRs. by Kanishka Basnayake (6796661)

“…Initially, <i>n</i>_<i>Ca</i> = 8 and decreases exponentially with a time constant of 360 ms. …”

Profile-QSAR and Surrogate AutoShim Protein-Family Modeling of Proteases by Prasenjit Mukherjee (2041477)

“…Analysis suggested that the higher structural diversity of the protease structures, as well as smaller assay data sets and fewer potent compounds, both contributed to the decreased predictive power. In a prospective virtual screening application, 32 compounds were ordered from a 1.5 million archive and tested in a biochemical assay. …”

Flow cytometry results showing reduced numbers of GFP-positive NALM6 cells and increased cell death after pEGFP-TES transfection. by Robert J. Weeks (3176793)

“…<p>Transfected NALM6 cells (24 hours post-transfection) were labelled with Annexin V and VLD and analysed by flow cytometry. (A) Decreased numbers of GFP-positive NALM6 cells were present after pEGFP-TES transfection (p<0.001). …”

RNA sequencing of key brain regions in <i>Trappc9</i> deficient mice. by Zhengzheng S. Liang (9333660)

“…<p>(A) <i>Trappc9</i> transcripts abundance showed 18%, 53% and 74% reduction compared to the wild-type expression level in hippocampus, (B) and decreased by 23%, 63% and 79% of the wild-type expression level in hypothalamus (average expression across 5 females per genotype). …”

Bifurcation figures of the S-I-P-B dynamics, presenting maximum and minimum values (black circles), as well as equilibrium densities when competitor (<i>B</i>) is not present (red... by Ilona Merikanto (115920)

“…<p>In all the figures <i>f_PB</i> = 10⁻⁷. a) When outside-host growth rate of pathogen (<i>r_P</i>) is 0.05 and the competition coefficient (<i>f_BP</i>) is 10⁻⁵, decreasing <i>r_S</i> destabilizes the disease dynamics. b) When <i>r_P</i> is (0.05) and <i>f_BP</i> is higher (10⁻⁴), pathogen population is able to increase and the dynamics are locally stable and all four populations coexist.…”

Image_1_Weaning Age Affects the Development of the Ruminal Bacterial and Archaeal Community in Hu Lambs During Early Life.JPEG by Huiling Mao (6520772)

“…Compared to W30, PW30 had a decreased relative abundance of Bacteroidetes. …”

Table_1_Weaning Age Affects the Development of the Ruminal Bacterial and Archaeal Community in Hu Lambs During Early Life.DOCX by Huiling Mao (6520772)

“…Compared to W30, PW30 had a decreased relative abundance of Bacteroidetes. …”