Table 1_Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.xlsx by Maria Jordan (10265489)

“…</p>Methods<p>In silico modeling of dysregulated pathways in IPF and screening for putative interfering small molecules identified carvedilol as a promising anti-fibrotic agent. We validated drug-mediated effects on key features of fibroblast activation in functional assays and gene expression analyses in human embryonic lung fibroblasts (MRC-5). …”

Table_4_Clinical Features of 50 Patients With Primary Adrenal Lymphoma.DOCX by Yan Wang (15435)

“…<p>Background and Objective: Primary adrenal lymphoma is a rare, progressive, easily misdiagnosed adrenal tumor with a poor prognosis. …”

Image_2_Pharmacological Inhibition of Amyloidogenic APP Processing and Knock-Down of APP in Primary Human Macrophages Impairs the Secretion of Cytokines.TIF by Philipp Spitzer (686930)

“…Still, it is unclear whether this can be attributed to the lack of APP or to the missing secretion of Aβ peptides. We inhibited the secretion of Aβ peptides in primary human monocyte derived macrophages with the γ-secretase inhibitor N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine-t-butyl-ester (DAPT) or the β-secretase inhibitor GL-189. …”

Table_1_Temperature-Dependent Lipid Accumulation in the Polar Marine Microalga Chlamydomonas malina RCC2488.docx by Daniela Morales-Sánchez (9911739)

“…Previously, when the polar marine microalga Chlamydomonas malina RCC2488 was cultivated under both nitrogen replete and depleted conditions at 8°C, it accumulated lipids and carbohydrates (up to 32 and 49%, respectively), while protein synthesis decreased (up to 15%). We hypothesized that the cultivation temperature had a more significant impact on lipid accumulation than the nitrogen availability in C. malina. …”

Supplementary file 1_Synergistic effects of potassium and gibberellin on the yield and quality of yellow pitahaya (Hylocereus megalanthus) fruits in the Peruvian Amazon.docx by Julio Cesar Santos-Pelaez (22674113)

“…The combination of 100 kg K₂O ha⁻¹ and 50 mg L⁻¹ GA₃ significantly improved fruit performance, with fruit weight (369.5 g), yield (12 t ha⁻¹), volume (322 cm³), and soluble solids (22.8°Brix), while acidity decreased (pH 4.87 vs. 4.55 in the control). …”

Voltage Profile Improvement in Case 2. by Biniam Alemayehu (22530422)

“…Results show that the proposed method reduces active power losses by 72.064%, decreases voltage deviation from 24.63% to 4.5% and improves the minimum bus voltage from 0.7537 pu to 0.9550 pu. …”

Cellular functions misregulated by HDACi after 48 h schistosomula treatment. by Letícia Anderson (2543926)

“…<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0005539#pntd.0005539.s005" target="_blank">S5 Table</a> gives the corresponding Smp gene information for each gene symbol present in this figure.…”

Image_4_Photosynthetic response of Chlamydomonas reinhardtii and Chlamydomonas sp. 1710 to zinc toxicity.TIF by Di Zhan (14842687)

“…The results demonstrated that Chlamydomonas sp. 1710 was much more tolerant to Zn than C. reinhardtii, with the half-maximal inhibitory concentration (IC50) values of 225.4 mg/L and 23.4  mg/L, respectively. The μ and Chl-a content of C. reinhardtii decreased in the presence of 15  mg/L Zn, whereas those of Chlamydomonas sp. 1710 were unaffected by as high as 100  mg/L Zn. …”

Table_1_Clinical Features of 50 Patients With Primary Adrenal Lymphoma.DOCX by Yan Wang (15435)

“…<p>Background and Objective: Primary adrenal lymphoma is a rare, progressive, easily misdiagnosed adrenal tumor with a poor prognosis. …”

Tight Chk1 Levels Control Replication Cluster Activation in <i>Xenopus</i> by Marie Platel (750508)

“…In the <i>Xenopus in vitro</i> system initiations are not sequence dependent and 2-5 origins are grouped in clusters that fire at different times despite a very short S phase. …”

Prediction of 30-day pediatric unplanned hospitalizations using the Johns Hopkins Adjusted Clinical Groups risk adjustment system by Mitchell G. Maltenfort (7252064)

“…Patients in the top 5% of risk scores accounted for 43% and the top 1% of risk scores accounted for 20% of all unplanned hospitalizations.…”

Image_1_Pharmacological Inhibition of Amyloidogenic APP Processing and Knock-Down of APP in Primary Human Macrophages Impairs the Secretion of Cytokines.tif by Philipp Spitzer (686930)

“…Still, it is unclear whether this can be attributed to the lack of APP or to the missing secretion of Aβ peptides. We inhibited the secretion of Aβ peptides in primary human monocyte derived macrophages with the γ-secretase inhibitor N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine-t-butyl-ester (DAPT) or the β-secretase inhibitor GL-189. …”

YFPγ2 fluorescence correlates with immunostaining of inhibitory postsynaptic, but not excitatory postsynaptic sites. by Adam Bleckert (336341)

“…<p>(<b>A, C</b>) Vertical sections from P12 and P21 retinas immunostained with anti-GABA_AR α1 raised in different hosts. …”

Inventory of ferns and lycophytes within forest fragments of Araucaria in southern Brazil by Ivanete Teresinha Mallmann (5694908)

“…For the floristic inventory, a parcel of 1 ha (100x100m) was demarcated inside three fragments, which were classified by size: large (246 ha - H1LF), medium (57 ha - H2MF) and small (5.2 ha - H3SF). …”

DataSheet_1_The Interaction of Arbuscular Mycorrhizal Fungi and Phosphorus Inputs on Selenium Uptake by Alfalfa (Medicago sativa L.) and Selenium Fraction Transformation in Soil.do... by Qi Peng (702503)

“…In our results, shoot Se concentration decreased, but plant Se content increased significantly as P level increased and had a significant positive correlation with AMF colonization rate. …”

Thermal/Optical Methods for Elemental Carbon Quantification in Soils and Urban Dusts: Equivalence of Different Analysis Protocols by Yongming Han (498643)

“…The soot concentrations agreed with EC from CTO-375, a pure thermal method.</p> </div>…”

Elevated levels of Wg or Zfh2 inhibit the regenerative behavior of hinge cells. by Michelle Ledru (6593078)

“…<p>(A-E) Expression trajectories of five genes from the ORA groups on tissue development and specification. …”

Proteomic Analysis of Drug-Resistant Mycobacteria: Co-Evolution of Copper and INH Resistance by Yuling Chen (438010)

“…The mc²155-Cu strain has a 5-fold higher resistance to copper sulfate and a 2-fold higher resistance to isoniazid (INH) than its parental strain mc²155, respectively. …”

Identification of <i>Drosophila</i> Gene Products Required for Phagocytosis of <i>Leishmania donovani</i> by Adam Peltan (112024)

“…Screening with dsRNAs from 1920 conserved metazoan genes has identified transcripts that, when reduced in expression, cause either increased or decreased phagocytosis. Focussing on genes in the latter class, RNAi-mediated knockdown of the small GTPase Rab5, the prenylated SNARE protein YKT6, one sub-unit of serine palmitoyltransferase (<i>spt2/lace),</i> the Rac1-associated protein Sra1 and the actin cytoskeleton regulatory protein, SCAR, all lead to a significant reduction in parasite phagocytosis. …”

Image_1_Anti-thrombosis Effects and Mechanisms by Xueshuantong Capsule Under Different Flow Conditions.TIF by Shuxian Han (6310388)

“…Under 0.9 Pa flow, XST at a concentration of 0.15 g⋅L^-1 reduced the platelets activation by 29.5%, and aspirin (ASA) showed no inhibitory effects. …”