Image_3_MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.jpeg by Xilong Kang (2548195)

“…The overexpression of miR-5112 decreased inflammatory cytokine production, accompanied by a reduction of IKKγ in flagellin-stimulated BMDCs. …”

Image_4_Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients.TIF by Maximilianos Elkouris (175800)

“…Simultaneously, SNCA mRNA levels are increased in the nigra, while LRRK2 and PINK1 mRNA levels are decreased both in the nigra and the cerebellum of PD subjects compared to controls, indicating a possible correlation between the expression profile of the respective lncRNAs with their adjacent coding genes. …”

Image_2_Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients.TIF by Maximilianos Elkouris (175800)

“…Simultaneously, SNCA mRNA levels are increased in the nigra, while LRRK2 and PINK1 mRNA levels are decreased both in the nigra and the cerebellum of PD subjects compared to controls, indicating a possible correlation between the expression profile of the respective lncRNAs with their adjacent coding genes. …”

DataSheet6_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Proteomic Insight into Functional Changes of Proteorhodopsin-Containing Bacterial Species <i>Psychroflexus torquis</i> under Different Illumination and Salinity Levels by Shi Feng (1662253)

Fecal Microbial Composition of Ulcerative Colitis and Crohn’s Disease Patients in Remission and Subsequent Exacerbation by Edgar S. Wills (532537)

“…Thiopurine use was found to be a significant cause of clustering as shown by Principal Coordinate Analysis and was associated with decreases in bacterial richness (Choa1 501.2 vs. 847.6 in non-users; p<0.001) and diversity (Shannon index: 5.13 vs. 6.78, respectively; p<0.01).…”

Image 4_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Image_1_Pathogenicity Traits Correlate With the Susceptible Vitis vinifera Leaf Physiology Transition in the Biotroph Fungus Erysiphe necator: An Adaptation to Plant Ontogenic Resi... by Agnes Calonnec (6066989)

“…Using leaf age, we were able to accurately predict the susceptibility of the leaf: a leaf aged, on average, 13.3 days had a very high probability (0.8) of being susceptible, while this probability decreased to 0.5 one week later. …”

DataSheet4_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

complete data FOTS6639.xlsx by Andreas Nord (4533943)

“…This was likely driven by triggering of cerebral thermosensors in response to cooling of the poorly insulated head, the skin of which was 5.4oC colder at -30oC than at 0oC. Thermal conductance in winter was higher in yearling birds, probably because they were time/resource constrained from acquiring a high-quality plumage and sufficient fat reserves due to concomitant body growth. …”

Table_6_Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring.XLSX by Lisa J. Martin (228675)

“…Perinatal HP/LC and LP/HC exposures resulted in a decreased ability to clear glucose in the offspring, with reduced baseline insulin and glucose concentrations in the LP/HC group and a reduced insulin response post-glucose challenge in the HP/LC group. …”

Image_4_Apolipoprotein-E deficiency leads to brain network alteration characterized by diffusion MRI and graph theory.JPEG by Margaret Caroline Stapleton (17437713)

“…<p>Late-onset Alzheimer’s disease (LOAD) is a major health concern for senior citizens, characterized by memory loss, confusion, and impaired cognitive abilities. …”

DataSheet1_Comparative Toxicity Assessment of Kratom Decoction, Mitragynine and Speciociliatine Versus Morphine on Zebrafish (Danio rerio) Embryos.docx by Thenmoly Damodaran (11304312)

“…</p><p>Results: Kratom decoction at a concentration range of ≥500 μg/ml caused 100% mortality of zebrafish embryos and decreased the hatching rate in a concentration-dependent manner. …”

Table_2_Gut microbiome variation in pulmonary TB patients with diabetes or HIV comorbidities.docx by Portia Abena Morgan (11883253)

“…</p>Results<p>Compared to the healthy controls, the gut microbiome of all the TB cohorts was characterized by a significant decreased alpha diversity and significant compositional changes. …”

Table_1_Genome-wide association study of coleoptile length with Shanxi wheat.XLSX by Naicui Wei (12000617)

“…In total, nine stable genetic loci were identified via 3VmrMLM under the three conditions, explaining 2.94–7.79% of phenotypic variation. Five loci on chromosome 2B, 3A, 3B, and 5B have not been reported previously. …”

Table_3_Structure and Function of Oral Microbial Community in Periodontitis Based on Integrated Data.xlsx by Zhengwen Cai (10986837)

“…Objective<p>Microorganisms play a key role in the initiation and progression of periodontal disease. …”

Data_Sheet_1_Gut Microbiota Modulates Intestinal Pathological Injury in Schistosoma japonicum-Infected Mice.docx by Beibei Zhang (509356)

“…Depletion of the gut microbiota by antibiotics, or transfer of the gut microbiota from normal to infected mice decreased the levels of IL-4, IL-5, and IL-13 and promoted the production of cytokines and mRNA levels of IL-10 and TGF-β in infected mice. …”

DataSheet_2_Gut microbiome variation in pulmonary TB patients with diabetes or HIV comorbidities.pdf by Portia Abena Morgan (11883253)

“…</p>Results<p>Compared to the healthy controls, the gut microbiome of all the TB cohorts was characterized by a significant decreased alpha diversity and significant compositional changes. …”

Table_1_Glucocorticoid-Driven NLRP3 Inflammasome Activation in Hippocampal Microglia Mediates Chronic Stress-Induced Depressive-Like Behaviors.DOCX by Xiujing Feng (581203)

“…<p>Chronic stress is a key risk factor for depression, and microglia have been implicated in the pathogenesis of the disease. …”

The sensitivity of the transient and steady-state section of the postsynaptic response to changing the TM model parameters. by Alireza Ghadimi (13839874)

“…The steady section is the following part that PSCs converge to a value and remain unchanged. Considering <i>θ</i> = [<i>F</i>, <i>D</i>, <i>f</i>, <i>U</i>] the vectorized form of the parameters: <i>θ</i>_<i>blue</i> = [2, 0.05, 0.1, 0], <i>θ</i>_<i>red</i> = [1, 0.05, 0.1, 0] and <i>θ</i>_{<i>purple</i>} = [2, 0.5, 0.1, 0]. …”