HMGB1 Attenuates Cardiac Remodelling in the Failing Heart via Enhanced Cardiac Regeneration and miR-206-Mediated Inhibition of TIMP-3 by Federica Limana (216501)

“…HMGB1 also enhanced MMP2 and MMP9 activity and decreased TIMP-3 levels. Importantly, miR-206 expression 3 days after HMGB1 treatment was 4-5-fold higher than in control hearts and 20–25 fold higher that in sham operated hearts. …”

OB interneurons are diffusely activated by the contralateral olfactory inputs. by Florence Kermen (362513)

“…(H) The pairwise similarity in interneuron response as a function of the distance separating them (ipsilateral, <i>n</i> = 4 fish; contralateral, <i>n</i> = 5 fish, *<i>p</i> < 0.05; Student <i>t</i> test). …”

HIV-1 Diversity, Transmission Dynamics and Primary Drug Resistance in Angola by Inês Bártolo (232611)

“…Evolutionary trends were determined by comparison with a similar survey performed in 2001.</p><p>Results</p><p>47.1% of the viruses were pure subtypes (all except B), 47.1% were recombinants and 5.8% were untypable. …”

Stimulation of pp65-specific CD4+ T cells increased production of stainable IFNγ, MIP-1α and MIP-1β and their respective mRNA, but not RANTES and its mRNA. by Joseph P. Casazza (257693)

“…B) PBMC were incubated with overlapping pp65 peptides, anti-CD154 PE, anti-CD107a Alexa680 and monensin for 5 hr. Cells were then stained as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000646#s4" target="_blank">Materials and Methods</a>, and live CD14⁻CD19⁻CD3⁺CD8⁻CD4⁺ memory cells were sorted into CD107⁻CD154⁻, CD107⁻CD154⁺ and CD107⁺CD154⁺ populations as shown. …”

Table_1_Biofilm Forming Antibiotic Resistant Gram-Positive Pathogens Isolated From Surfaces on the International Space Station.docx by Lydia-Yasmin Sobisch (6476684)

“…The number of recovered bacteria decreased significantly from V2A to V2A-Ag to AGXX®. …”

The Genetic Legacy of the Pre-Colonial Period in Contemporary Bolivians by Patricia Taboada-Echalar (392334)

“…Bolivia shows a decreasing autosomal molecular diversity pattern along the longitudinal axis, from the Altiplano to the lowlands. …”

Data_Sheet_1_Epidemiology of Pneumocystis jirovecii Pneumonia and (Non-)use of Prophylaxis.docx by Albert Dunbar (8848394)

“…An in-house PJ quantitative PCR (qPCR) was used in each center. A cycle threshold (Ct) value of ≤ 28.5–30 was considered a probable PCP. …”

Comparison of model results with animal interaction data. by Joseph Hickey (6274097)

“…<p>(a) David’s Scores, <i>D</i>, calculated from the mountain goat interaction data of Ref. …”

Total strain energy of fibroblasts on SU-8 nanopillar arrays. by Jasper Foolen (3088503)

“…Pillars have a diameter of 250nm, a height of 1.5μm and center to center distance was 800nm. …”

Delayed centrosome maturation causes asymmetric particle partitioning. by Jing Chen (4762)

“…(B) Time series of dynein distribution with ∼5 min time delay between the centrosome maturation (also see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034919#pone.0034919.s008" target="_blank">Movie S4</a>). …”

Table 1_Bevacizumab and anlotinib combination therapy acts via HIF-1α suppression to exert synergistic anti-angiogenic and anti-tumor effects in non-small cell lung cancer.docx by Nafeisha Simayi (22262161)

“…B+A inhibited cell viability by 78%, colony formation by 90%, and invasion by 75% in NSCLC cell lines A549 and H1299; downregulated N-cadherin 5.34-fold, vimentin 6.46-fold, and α-SMA 4.35-fold; and upregulated E-cadherin 3.75-fold. …”

Bis(β-diketiminate) Rare-Earth-Metal Borohydrides: Syntheses, Structures, and Catalysis for the Polymerizations of l‑Lactide, ε‑Caprolactone, and Methyl Methacrylate by Xiaodong Shen (1542499)

“…The <i>M</i>_n(obsd) values (<i>M</i>_n = the number-average molar mass) of the resulting PCL are in good agreement with <i>M</i>_n(calcd), with a ratio of monomer to <b>6</b> of up to 1000. The polymerization kinetics of l-LA in THF at 20 °C by complex <b>6</b> displays a first-order dependence on the monomer concentration. …”

Pathogen-Induced AgDscam Splice Form Repertoires Have Increased Affinity to, and Defense Activity against, the Eliciting Pathogen by Yuemei Dong (17509)

“…<div><p>(A) E. coli and P. veronii had increased affinity to both membrane-bound (M) and secreted (S) AgDscam splice form repertoires that were produced by Sua5B cells previously challenged with <i>E. coli (E.c.)…”

Image1_Optogenetic Manipulations of Amygdala Neurons Modulate Spinal Nociceptive Processing and Behavior Under Normal Conditions and in an Arthritis Pain Model.tiff by Mariacristina Mazzitelli (10869657)

“…Conversely, optical silencing of CeA–CRF neurons or of BLA axon terminals in the CeA decreased the evoked responses of spinal WDR neurons and vocalizations, but not hypersensitivity, in the arthritis pain model. …”

Image2_Optogenetic Manipulations of Amygdala Neurons Modulate Spinal Nociceptive Processing and Behavior Under Normal Conditions and in an Arthritis Pain Model.tiff by Mariacristina Mazzitelli (10869657)

“…Conversely, optical silencing of CeA–CRF neurons or of BLA axon terminals in the CeA decreased the evoked responses of spinal WDR neurons and vocalizations, but not hypersensitivity, in the arthritis pain model. …”

Effects of <i>Tmem2</i> ablation on NCC development. by Toshihiro Inubushi (647748)

“…The ratio of migratory NCCs relative to the total number of NCCs was also compared between <i>Tmem2</i>^<i>CKO</i> and control embryos (<i>bottom graph</i>). Data represent means ± SD (<i>n</i> = 5). ***<i>p</i> < 0.001 by Student’s <i>t</i>-test. …”

DataSheet_1_Effectiveness of Regdanvimab Treatment in High-Risk COVID-19 Patients to Prevent Progression to Severe Disease.docx by Ji Yeon Lee (2295001)

“…</p>Conclusion<p>Regdanvimab treatment was associated with a decreased risk of progression to severe disease.…”

Image_2_Distinct Neutrophil Populations in the Spleen During PICS.TIF by Satarupa Sengupta (419942)

“…The CD54^hi population showed traditional, proinflammatory properties, but a relatively decreased chemotactic response, while CD54^lo cells had significantly higher chemotaxis, yet significantly decreased proinflammatory functions. …”

DataSheet_1_Effectiveness of Regdanvimab Treatment in High-Risk COVID-19 Patients to Prevent Progression to Severe Disease.docx by Ji Yeon Lee (2295001)

“…</p>Conclusion<p>Regdanvimab treatment was associated with a decreased risk of progression to severe disease.…”

Image_1_Distinct Neutrophil Populations in the Spleen During PICS.TIF by Satarupa Sengupta (419942)

“…The CD54^hi population showed traditional, proinflammatory properties, but a relatively decreased chemotactic response, while CD54^lo cells had significantly higher chemotaxis, yet significantly decreased proinflammatory functions. …”