Molecular Properties Determining Unbound Intracellular and Extracellular Brain Exposure of CNS Drug Candidates by Irena Loryan (1681075)

“…In the present work we sought to gain a mechanistic understanding of the physicochemical properties that influence the transport of unbound drug across the blood–brain barrier (BBB) as well as the intra- and extracellular drug exposure in the brain. …”

High-Resolution Linkage Analyses to Identify Genes That Influence <em>Varroa</em> Sensitive Hygiene Behavior in Honey Bees by Jennifer M. Tsuruda (122483)

“…<div><p><em>Varroa</em> mites (<em>V. destructor</em>) are a major threat to honey bees (<em>Apis melilfera</em>) and beekeeping worldwide and likely lead to colony decline if colonies are not treated. …”

Nicotine promotes the development of oral leukoplakia via regulating peroxiredoxin 1 and its binding proteins by Moci Qi (12728326)

Mitral Repair by Minimally Invasive Approach by Daniel Navia (4732464)

Supplementary Material for: Association of Cancer and Its Interaction with Conventional Risk Factors on Cardiovascular Disease Risk by Suzuki Y. (3596711)

Supplementary Material for: Association of Cancer and Its Interaction with Conventional Risk Factors on Cardiovascular Disease Risk by Suzuki Y. (3596711)

Data_Sheet_1_Fatty Acid Profiles of Serum Lipid Fractions Change Minimally in Sled Dogs Before and After Short Bouts of Exercise.PDF by James R. Templeman (9238741)

“…<p>Although emerging data suggests a greater influence of gluconeogenic precursors, endurance sled dogs have long appeared to rely heavily on fatty acid oxidation for sustained energy production. …”

Viral manipulation of the STAT3 signaling pathway. by Armando Andres Roca Suarez (4967134)

“…EBNA2, Epstein–Barr virus nuclear antigen 2; EBV, Epstein–Barr virus; HBV, hepatitis B virus; HBx, hepatitis B virus X protein; HCMV, human cytomegalovirus; HCV, hepatitis C virus; HEV, hepatitis E virus; hMPV, human metapneumovirus; IAV, influenza A virus; IE1, intermediate-early protein 1; IL-6, interleukin 6; IL-10, interleukin 10; IRAK1, interleukin 1 receptor-associated kinase 1; JAK1, Janus kinase 1; KSHV, Kaposi’s sarcoma-associated herpesvirus; LMP1, latent membrane protein 1; miRNA, microRNA; MeV, measles virus; MK2, mitogen-activated protein kinase 2; MuV, mumps virus; NS5A, non-structural protein 5A; NSs, non-structural proteins; P, phosphorylation; PKCδ, protein kinase C delta type; PTPRD, receptor-type tyrosine-protein phosphatase D; RABV, rabies virus; ROS, reactive oxygen species; RVFV, Rift Valley fever virus; SOCS3, suppressor of cytokine signaling 3; STAT3, signal transducer and activator of transcription 3; TRIM28, tripartite motif-containing protein 28; u-STAT3, unphosphorylated STAT3; vIL-10, viral IL-10; vIL-6, viral IL-6; VZV, varicella-zoster virus; ZIKV, Zika virus.…”

Thermal biology and growth of bison (Bison bison) along the Great Plains: testing four theories of endotherm body size: dataset by Jeff M. Martin (6948683)

Table_1_Accelerometer-measured physical activity and sample-based frailty in older women: does pattern really matter?.DOCX by Ting Li (117885)

“…Additionally, bouted and sporadic MVPA were associated with decreased odds of being slow and their optimal cutoff values were 5 and 19.1 min/day, respectively. …”

Image_4_Trichinella spiralis Thioredoxin Peroxidase 2 Regulates Protective Th2 Immune Response in Mice by Directly Inducing Alternatively Activated Macrophages.TIF by Qi-Wang Jin (5392352)

“…Immunization of BALB/c mice with rTsTPX2 could induce a Th1-suppressing mixed immune response given the increased levels of Th2 cytokines (IL-4 and IL-10) production along with the decreased levels of Th1 cytokines (IFN-γ, IL-12, and TNF-α). …”

Image_2_Trichinella spiralis Thioredoxin Peroxidase 2 Regulates Protective Th2 Immune Response in Mice by Directly Inducing Alternatively Activated Macrophages.TIF by Qi-Wang Jin (5392352)

“…Immunization of BALB/c mice with rTsTPX2 could induce a Th1-suppressing mixed immune response given the increased levels of Th2 cytokines (IL-4 and IL-10) production along with the decreased levels of Th1 cytokines (IFN-γ, IL-12, and TNF-α). …”

HBP1 regulates UHRF1 expression. by Ruixiang Yang (10453370)

“…<p>(A) IHC staining of HBP1 and UHRF1 in pathological sections of cancer patients (<i>n =</i> 12/group). Scale bar = 100 μm. (B) Two-tailed Pearson correlation analysis method was used to calculate the correlation between the expression of HBP1 and UHRF1. …”

Image_3_Trichinella spiralis Thioredoxin Peroxidase 2 Regulates Protective Th2 Immune Response in Mice by Directly Inducing Alternatively Activated Macrophages.TIF by Qi-Wang Jin (5392352)

“…Immunization of BALB/c mice with rTsTPX2 could induce a Th1-suppressing mixed immune response given the increased levels of Th2 cytokines (IL-4 and IL-10) production along with the decreased levels of Th1 cytokines (IFN-γ, IL-12, and TNF-α). …”

Image_1_Trichinella spiralis Thioredoxin Peroxidase 2 Regulates Protective Th2 Immune Response in Mice by Directly Inducing Alternatively Activated Macrophages.TIF by Qi-Wang Jin (5392352)

“…Immunization of BALB/c mice with rTsTPX2 could induce a Th1-suppressing mixed immune response given the increased levels of Th2 cytokines (IL-4 and IL-10) production along with the decreased levels of Th1 cytokines (IFN-γ, IL-12, and TNF-α). …”

lncCyt b cooperates with hnRNPA2B1 to modulate glycolysis and exhibits physiological significance. by Jia Li (160557)

“…<p>(A) Native RIP followed by RT-qPCR detecting MDL1AS, lncND5 and lncCyt b retrieved by anti-hnRNPA2B1 antibody, or by normal IgG and anti-P53 antibody, in whole-cell, nuclear, or cytoplasmic lysates of A549 cells. …”

Analysis of apoptosis and protein changes after knock-down of RhoGDIα. by Li Wang (15202)

“…<p>A. Apoptosis of human PDL cells subjected to 20% cyclic strain for 24 h was determined by flow cytometry of cells stained with annexin V and PI. …”

Ca²⁺ homeostasis and the corpuscles of Stannius regulate sensory gating. by Susannah S. Schloss (21238775)

“…<p><b>(A–D)</b> E3 media with differing Ca²⁺ concentrations were applied to WT larvae at 5 dpf. …”

Table_1_Dosimetric Evaluation of Commercially Available Flat vs. Self-Produced 3D-Conformal Silicone Boluses for the Head and Neck Region.xlsx by Stephan Pollmann (2821559)

“…Increasing the surface–bolus distance from 5 to 10 mm decreased the surface dose by approximately 2% and 11% in the 6 × 6- and 3 × 3-cm² fields, respectively. …”

Table 1_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…</p>Methods<p>In this study, we employed Mendelian randomization (MR) to establish a robust potential link between gut microbial genera and CRC. …”