Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells by Tanja Waldmann (7379)

“…Our findings suggest the use of the highest noncytotoxic drug concentration for gene array toxicogenomics studies, as higher concentrations possibly yield wrong information on the mode of action, and lower drug levels result in decreased gene expression changes and thus a reduced power of the study.…”

The response to ultrasound depends on bilayer curvature. by Martin Loynaz Prieto (475819)

“…</b> Capacitive currents at −200 mV in response to a 1-MHz, 610-mW/cm² ultrasound pulse with different solution volumes in the lower compartment of the bilayer chamber (<i>left</i>), along with illustrations of the inferred resting-state bilayer curvature (<i>right</i>). …”

Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells by Tanja Waldmann (7379)

“…Our findings suggest the use of the highest noncytotoxic drug concentration for gene array toxicogenomics studies, as higher concentrations possibly yield wrong information on the mode of action, and lower drug levels result in decreased gene expression changes and thus a reduced power of the study.…”

Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells by Tanja Waldmann (7379)

“…Our findings suggest the use of the highest noncytotoxic drug concentration for gene array toxicogenomics studies, as higher concentrations possibly yield wrong information on the mode of action, and lower drug levels result in decreased gene expression changes and thus a reduced power of the study.…”

Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells by Tanja Waldmann (7379)

“…Our findings suggest the use of the highest noncytotoxic drug concentration for gene array toxicogenomics studies, as higher concentrations possibly yield wrong information on the mode of action, and lower drug levels result in decreased gene expression changes and thus a reduced power of the study.…”

Influence of Soil Type, Cultivar and <i>Verticillium dahliae</i> on the Structure of the Root and Rhizosphere Soil Fungal Microbiome of Strawberry by Srivathsa Nallanchakravarthula (649524)

“…Inoculation with the pathogen <i>V. dahliae</i> had a significant influence on community structure, generally decreasing the number of rhizosphere soil- and root-inhabiting fungi. …”

Stit is required for optimal growth of the wing epithelium. by Fergal O'Farrell (435865)

“…(C) The expression of <i>Stit^KD</i> in the dorsal wing compartment led to a 33% reduction of the dorsal/ventral (D/V) cell number ratio (>15,000 cells from 10 <i>Stit^KD</i> pupal wings counted) relative to <i>GFP</i> expressing controls (8 animals, >15,000 cells counted). …”

Data Sheet 1_Characterization of the Vibrio anguillarum VaRyhB regulon and role in pathogenesis.docx by Yingjie Li (2106778)

“…It is unclear whether this upregulation model is mediated by a small RNA, RyhB. </p>Methods<p>The small RNA, VaryhB, was deleted in V. anguillarum strain 775, and its regulon was investigated using transcriptomic analysis. …”

GFP-MSCs recruited to human CRPC xenografts enhanced Wnt signaling. by Veronica R. Placencio (361478)

“…<p>A) The experimental setup is summarized in the timeline. …”

Bacterial components inhibit reverse transmigration. by Adarsh Gopinath (3360815)

Supplementary material 2. from Density independent decline from an environmentally transmitted parasite by Scott Carver (11313405)

The effect of NO on tumor growth. by Nadhir Yousfi (701929)

“…Images were taken at 1 dpi and 4 dpi. Images (A-A”‘) and (B-B”‘) show the tumors at 1 dpi and 4 dpi for control and CPTIO treated embryo. …”

Table_1_PAI-1 Exacerbates White Adipose Tissue Dysfunction and Metabolic Dysregulation in High Fat Diet-Induced Obesity.DOCX by Lin Wang (11986)

“…</p><p>Methods: Four- to five-weeks-old male C57B6/6J mice were fed a HFD (45%) for 14 weeks, while age-matched control mice were fed a standard laboratory chow diet (10% fat). …”

Image_1_Lipoxin-Induced Phenotypic Changes in CD115+LY6Chi Monocytes TAM Precursors Inhibits Tumor Development.TIF by Natália Mesquita de-Brito (6855914)

“…</p><p>Methods: Fourteen days after inducing B16-F10 melanoma tumors, mice received one single dose of ATL-1 (1 μg/i.v.), a lipoxin A4 analog. After further 7 days, blood and bone-marrow were collected, tumors and spleens were removed, and TAMs and blood monocytes were isolated.…”

Image_1_PAI-1 Exacerbates White Adipose Tissue Dysfunction and Metabolic Dysregulation in High Fat Diet-Induced Obesity.TIF by Lin Wang (11986)

“…</p><p>Methods: Four- to five-weeks-old male C57B6/6J mice were fed a HFD (45%) for 14 weeks, while age-matched control mice were fed a standard laboratory chow diet (10% fat). …”

Data_Sheet_1_Effects of Dietary Choline Levels During Pregnancy on Reproductive Performance, Plasma Metabolome and Gut Microbiota of Sows.docx by Wei Zhong (284774)

“…In addition, the plasma metabolome and gut microbiota of sows was studied. A total of 260 multiparous sows were allocated to five dietary treatment groups with increasing choline concentrations (1,050, 1,450, 1,850, 2,250, and 2,650 mg/kg) in a randomized complete block design. …”

Fig. S40. IVG plot of the depth and breadth of genome coverage obtained by the mapping to the 10-CrypGS<i> </i>reference file from double-enriched (D), single-enriched (S), and une... by Natalia J Bayona Vásquez (16388913)

Antisense inhibition of BDNF inhibits osteoclast formation and RANKL expression in myelomatous bones. by Li-Sha Ai (126640)

“…<p>(A) TRAP and H&E staining of the myelomatous bones. …”

The RT distributions of congruency sequence effect in the Stroop, word Flanker, and letter Flanker tasks. by Dandan Tang (383577)

“…<p>Panels <b>A, B, & C</b> illustrate the time courses of congruency sequence effect in Experiments 1, 2, & 3, respectively. …”

Supplementary Material for: First-in-human effects of PPT1 inhibition using the oral treatment with GNS561/ Ezurpimtrostat in patients with primary and secondary liver cancers by Harding J.J. (12088145)

“…Liver trough concentrations were much higher than in plasma a median time of 28 days of administration with a mean liver to plasma ratio of 9559 (Min 149-Max 25759), which is in accordance with rat preclinical data observed after repeated administration. …”