LRG1 modifies the effects of TGFβ on myeloid and hematopoietic progenitor cell growth. by Lawrence J. Druhan (376410)

“…A dose-response reduction in cell proliferation as measured by the decreasing A490-A650 is observed with increasing concentrations of TGFβ that is mitigated by the addition of LRG1. …”

GNB1 and SCARB2 involvement in lipid metabolism of human subcutaneous adipocytes. by Takuya Kitamoto (11721639)

“…Abbreviations: ADIPOQ, adiponectin, C1Q and collagen domain containing; α, alpha subunit of the G proteins; β, GNB1; C1P, ceramide-1-phosphate; Cer, ceramide; CERK, ceramide kinase; CDH13/T-cadherin, cadherin 13; CEPT, choline/ethanolaminephosphotransferase; ChE, cholesterol ester; Chol, cholesterol; DG, diacylglycerol; DGAT, diacylglycerol O-acyltransferase; ER, endoplasmic reticulum; G3P, glycero-3-phosphate; GPCR, G protein-coupled receptor; γ, gamma subunit of the G proteins; HSPA8/HSC70, heat shock protein family A; IP₃, inositol (1,4,5)-trisphosphate; LAMP1/2, lysosomal associated membrane protein 1/2; LPA, lysophosphatidic acid; NPC1/2, NPC intracellular cholesterol transporter 1/2; PA, phosphatidic acid; PC, phosphatidylcholine; PI, phosphatidylinositol; PLIN2, perilipin 2; PLPP1, phospholipid phosphatase 1; PLC, phospholipase C; PNPLA2/ATGL, patatin like phospholipase domain containing 2; SCARB2, scavenger receptor class B member 2; SGMS/SMS, sphingomyelin synthase; SM, sphingomyelin; SOAT, sterol O-acyltransferase; SPH, sphingosine; SQSTM1/p62, sequestosome 1; TG, triacylglycerol; TMT1A/METTL7A, methyltransferase-like protein 7A.…”

Table_1_The association between thyroid-stimulating hormone and thyroid nodules, goiter and thyroid antibody positivity.docx by Shaohan Li (10942453)

“…Low TSH levels (0.27–1.41 IU/mL) were identified as a risk factor for TN (odds ratio [OR], 1.46; 95% CI: 1.14-1.87) and GR (OR 5.90, 95% CI 2.27-15.3). …”

Image_1_Comparative efficiency of silica gel, biochar, and plant growth promoting bacteria on Cr and Pb availability to Solanum melongena L. in contaminated soil irrigated with was... by Umm e Rabiya (13197495)

“…<p>Crop irrigation with untreated wastewater is a routine practice in developing countries that causes multiple human health consequences. …”

Data Sheet 1_Comparative transcriptomics of two petal variants reveals key functional genes underlying petal shape development in lotus (Nelumbo).zip by Jiaxin He (11256475)

“…</p>Results<p>It revealed that the broad petal variation of M512 was caused by a reduction in petal length while maintaining width, whereas the narrow petal phenotype of CSFY resulted from a combination of increased length and decreased width. …”

The putatively encoded protein isoform smLRP1 is expressed in human tumour cell lines. by Marlen Kolb (759117)

“…GADPH expression served as control. (<b>A</b>) In the absence of secondary anti-mouse antibody (1:5,000), no smLRP1 protein band (32 kDa) could be detected in A459. …”

Manipulation of Lrrk enhances tau neurotoxicity. by Farah H. Bardai (6107924)

“…<p>(A) Increasing or decreasing <i>Drosophila</i> Lrrk enhances the toxicity of human tau^R406W, which is further enhanced by expressing mutant forms of Lrrk engineered to mimic Parkinson’s disease mutations. …”

Table_2_An etude for post-pandemic practice: The impact of the COVID-19 pandemic on practice methods and instrumental technique.DOCX by Ellen Fallowfield (14287268)

“…Participants were statistically more likely to report “never” watching online tutorials than “often” (p = 0.014), but, of those that did watch such material, 75% agreed that it had a positive impact upon their practice. Most participants created digital content during this period; only 5% produced no such material. …”

Supplementary materials: Cost–effectiveness of sotagliflozin for the treatment of patients with diabetes and recent worsening heart failure by Jaehong Kim (261471)

“…<b>Results:</b> Sotagliflozin use decreased annualized rehospitalization rates by 34.5% (0.228 vs 0.348, difference: -0.120), annualized emergency department visits by 40.0% (0.091 vs 0.153, difference: -0.061) and annualized mortality by 18.0% (0.298 vs 0.363, difference: -0.065) relative to standard of care, resulting in a net gain in QAYs of 0.425 for sotagliflozin versus standard of care. …”

<b>Long-term evaluation of pollution</b><b>dynamics</b><b>in West Lake Taihu, China: Enhanced WQI and TLI models for improved accuracy and management relevance</b> by Bo Chao (1916083)

“…Results showed that total phosphorus (TP) and total nitrogen (TN) were the dominant factors influencing both water quality and eutrophication, replacing traditional dissolved oxygen (DO) and chlorophyll-a (Chl-a). RF and exceedance rate analyses confirmed TP (24.79%) and TN (19.51%) as the primary contributors to WQI, with exceedance rates > 80%, while DO showed little influence (< 9%) and an exceedance rate below 5%. …”

Flow chart for inclusion and exclusion criteria. by Maleda Tefera (9025154)

“…Specifically, the prevalence of stunting was 42.9% (95% CI: 42.14, 43.56), followed by underweight at 30.28% (95% CI: 29.63, 30.92), and wasting at 13.84% (95% CI: 13.35, 12.04).Children breastfed into their third year of life were more likely to develop underweight (AOR: 1.55; 95% CI 1.41, 1.70) and stunting (AOR: 5.45; 95% CI 4.83, 6.15). Conversely, the likelihood of wasting decreased in children breastfeeding in their second and third year of life (AOR: 0.75; 95% CI 0.67, 0.83) and (AOR: 0.50; 95% CI 0.43, 0.60) respectively. …”

Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney... by Rajiv Agarwal (12950)

“…<p dir="ltr">Objective: The CONFIDENCE trial demonstrated additive benefits of simultaneous initiation of finerenone, a nonsteroidal mineralocorticoid receptor antagonist, and a sodium-glucose cotransporter 2 (SGLT2) inhibitor compared to monotherapy in reducing urinary albumin-to-creatinine ratio (UACR). …”

Charge Distribution in Chromium and Vanadium Catecholato Complexes:  X-ray Absorption Spectroscopic and Computational Studies by Carsten Milsmann (1758994)

“…</i> <b>2004</b>, <i>43</i>, 462−465) to a Cr(III) monocatecholato complex, [Cr(tren)(cat)]⁺ (tren = tris(2-aminoethyl)amine, cat = catecholato(2−)), and its oxidized analogue, as well as to a series of V(V/IV/III) triscatecholato complexes ([VL₃]<i>ⁿ</i>^-, where <i>L</i> = cat, 3,5-di-<i>tert</i>-butylcatecholato(2−), or tetrachlorocatecholato(2−), and <i>n</i> = 1−3). …”

When Contact Is Not Enough: Affecting First Year Medical Students’ Image towards Older Persons by Sasmita Kusumastuti (3686185)

“…The percentage of students considering over 75 years as being old increased from 17.2% to 31.2% (p < 0.01) and those who thought they would find as much satisfaction in care for older as for younger patients decreased from 78.5% to 62.1% (p < 0.001). Exploratory principal component analysis showed particularly low scores on ‘comportment’ and ‘pleasurable interaction’ whereas the scores on ‘personality traits’ and ‘habitual behaviour’ significantly deteriorated (both p < 0.001). …”

RNAi-mediated gene knockdown alters horn shapes and sizes in head and thorax. by Takahiro Ohde (120422)

“…<p><b>(A</b>–<b>K)</b> RNAi effects on horn shapes. (<b>A)</b> Dorsal view of head horn and prothorax in an <i>EGFP</i> RNAi beetle. …”

Chiral Propargylic Cations as Intermediates in S_N1‑Type Reactions: Substitution Pattern, Nuclear Magnetic Resonance Studies, and Origin of the Diastereoselectivity by Dominik Nitsch (1783768)

“…Products were formed consistently with a diastereomeric ratio larger than 95:5 in favor of the <i>anti</i>-diastereoisomer. …”

Synthesis of Few-Layer Graphene by Peeling Graphite Flakes via Electron Exchange in Solution Plasma by Sangwoo Chae (4515772)

“…X-ray diffraction measurements revealed that the intensity of the 002 diffraction of graphite and the crystallite size along the [001] direction decreased to about 5 nm after SP treatment, indicating the progress of graphite flake peeling. …”

Image_1_Cyclic Stretch Induces Vascular Smooth Muscle Cells to Secrete Connective Tissue Growth Factor and Promote Endothelial Progenitor Cell Differentiation and Angiogenesis.TIF by Jing Yan (312090)

“…In vitro, EPCs were cocultured with VSMCs, which were exposed to cyclic stretch at a magnitude of 5% (which mimics physiological stretch) and a constant frequency of 1.25 Hz for 12 h. …”

Study population. by Madhurima Roy (9745137)

“…Plasma levels of neutrophil chemo-attractants CXCL8/1/2/5, CCL2 and 20 and cytokines, (IL-6, IFN-γ, IL-4, IL-10, TNF-α, IL-17 and IL-22, 23) were evaluated by a multiplex assay, while lesional expression of IL-8, IL-10 and IL-17 was evaluated by immunohistochemistry. …”

<i>Lefty1</i> and <i>Lefty2</i> are regulated by separate proximal enhancer regions in mouse embryonic stem cells. by Tiegh Taylor (5791382)

“…Strand specific GRO-seq data is shown, bidirectional transcription is a marker of active enhancers. The locations of previously identified enhancers active at embryonic day 8.5 are shown (ASE, LPE, NPE). …”