Figure 4 from SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance by Marta J. Llorca-Cardenosa (14961612)

“…<b>O,</b> SMG8 and SMG9 mutant cells present decreased forks ratio (a.u.) compared with the WT cells in a DNA fiber assay after 24 hours of 300 nmol/L berzosertib exposure (20 minutes incubation with 25 μmol/L IdU and 20 minutes incubation with 125 μmol/L CIdU). …”

The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane by Rizk, Nasser M

“…Sulforaphane (SFN) has been suggested as a new potential anti-diabetic compound acting by reducing blood glucose levels through mechanisms not fully understood (1). …”
Get full text
Get full text

Synthesis and Reactivity of Haloacetato Derivatives of Iron(II) Including the Crystal and the Molecular Structure of [Fe(CF₃COOH)₂(μ-CF₃COO)<sub>2<... by Fabio Marchetti (1322487)

“…Fe(CF₃COO)₂(DMF)<i>_x</i>, as obtained from Fe(CO)₅ and CF₃COOH/(CF₃CO)₂O in DMF, reacts with dioxygen at room temperature to give two μ₃-oxo compounds, namely, [Fe₃(μ₃-O)(CF₃COO)₆(DMF)₃], <b>3</b>, a Fe^(II)−Fe^(III)−Fe^(III) derivative, and [Fe₄(μ₃-O)₂(μ₂-CF₃COO)₆(CF₃COO)₂(DMF)₄], <b>4</b>, containing Fe(III) atoms only, which have been characterized by X-ray diffraction methods. …”

Synthesis and Reactivity of Haloacetato Derivatives of Iron(II) Including the Crystal and the Molecular Structure of [Fe(CF₃COOH)₂(μ-CF₃COO)<sub>2<... by Fabio Marchetti (1322487)

“…Fe(CF₃COO)₂(DMF)<i>_x</i>, as obtained from Fe(CO)₅ and CF₃COOH/(CF₃CO)₂O in DMF, reacts with dioxygen at room temperature to give two μ₃-oxo compounds, namely, [Fe₃(μ₃-O)(CF₃COO)₆(DMF)₃], <b>3</b>, a Fe^(II)−Fe^(III)−Fe^(III) derivative, and [Fe₄(μ₃-O)₂(μ₂-CF₃COO)₆(CF₃COO)₂(DMF)₄], <b>4</b>, containing Fe(III) atoms only, which have been characterized by X-ray diffraction methods. …”

ISOTT2021_Takahashi by Eiji Takahashi (7467422)

“…<div>These are supplemental materials for my presentation in ISOTT2021 (a remote meeting) entitled " On the mechanisms of sustained mitochondrial membrane potential without functioning complex IV".…”

Transcriptional alterations of genes related to fertility decline in male rats induced by chronic sleep restriction by Wenyang Chen (8430798)

“…</p> <p><b>Abbreviations</b>: CSR: chronic sleep restriction; SD: sleep deprivation; RNA-Seq: RNA sequencing; NGS: next generation sequencing; qRT-PCR: real-time quantitative reverse transcription polymerase chain reaction; KEGG: Kyoto encyclopedia of genes and genomic; NO: nitric oxide; INOS: Inducible nitric oxide synthase; Il6: interleukin-6; Tnf: tumour necrosis factor alpha; Hsd11b1: hydroxysteroid 11-beta dehydrogenase 1; Dnmt3a: DNA methyltransferase 3Ax; PSD: paradoxic sleep deprivation; DNMTs: DNA methyltransferases family; REM: rapid eye movement sleep; PGD: preimplantation genetic diagnosis; PGS: preimplantation genetic screening; ECS: expanded carrier screening; T: testosterone; FSH: follicle stimulating hormone; LH: luteinizing hormone; PRL: prolactin; BC group: Blank Control group; MC group: Model Control group; Hist1h2ba: histone cluster 1 H2ba; Lgr4: leucine-rich repeat-containing G protein-coupled receptor 4; Atrn: attractin ; Ogg1: 8-oxoguanine DNA glycosylase; SNVs: single nucleotide variants ; HPG axis: hypothalamic-pituitary-adrenal axis; Star protein: steroid acute regulatory protein; Dmac2l: distal membrane arm assembly complex 2 like; Esr1: estrogen receptor 1; MAPK pathways: mitogen-activated protein kinase pathways; Sos2: SOS Ras/Rho guanine nucleotide exchange factor 2; Jak2: Janus kinase 2; Pik3cb: phosphatidylinositol-4,5-bisphosphate 3-kinase, and catalytic subunit beta; Kras: KRAS proto-oncogene and GTPase; RRBS: reduced representation bisulfite sequencing; DEGs: differently expressed genes; SPF: Specific Pathogen Free; HE: hematoxylin & eosin; DMR: differentially methylated region; GO Analysis: Gene Ontology analysis; SINE: short interspersed nuclear elements; LINE: long interspersed nuclear elements; LTR: long terminal repeats</p>…”

Synthesis and Reactivity of Haloacetato Derivatives of Iron(II) Including the Crystal and the Molecular Structure of [Fe(CF₃COOH)₂(μ-CF₃COO)<sub>2<... by Fabio Marchetti (1322487)

“…Fe(CF₃COO)₂(DMF)<i>_x</i>, as obtained from Fe(CO)₅ and CF₃COOH/(CF₃CO)₂O in DMF, reacts with dioxygen at room temperature to give two μ₃-oxo compounds, namely, [Fe₃(μ₃-O)(CF₃COO)₆(DMF)₃], <b>3</b>, a Fe^(II)−Fe^(III)−Fe^(III) derivative, and [Fe₄(μ₃-O)₂(μ₂-CF₃COO)₆(CF₃COO)₂(DMF)₄], <b>4</b>, containing Fe(III) atoms only, which have been characterized by X-ray diffraction methods. …”

Synthesis and Reactivity of Haloacetato Derivatives of Iron(II) Including the Crystal and the Molecular Structure of [Fe(CF₃COOH)₂(μ-CF₃COO)<sub>2<... by Fabio Marchetti (1322487)

“…Fe(CF₃COO)₂(DMF)<i>_x</i>, as obtained from Fe(CO)₅ and CF₃COOH/(CF₃CO)₂O in DMF, reacts with dioxygen at room temperature to give two μ₃-oxo compounds, namely, [Fe₃(μ₃-O)(CF₃COO)₆(DMF)₃], <b>3</b>, a Fe^(II)−Fe^(III)−Fe^(III) derivative, and [Fe₄(μ₃-O)₂(μ₂-CF₃COO)₆(CF₃COO)₂(DMF)₄], <b>4</b>, containing Fe(III) atoms only, which have been characterized by X-ray diffraction methods. …”

Synthesis and Reactivity of Haloacetato Derivatives of Iron(II) Including the Crystal and the Molecular Structure of [Fe(CF₃COOH)₂(μ-CF₃COO)<sub>2<... by Fabio Marchetti (1322487)

“…Fe(CF₃COO)₂(DMF)<i>_x</i>, as obtained from Fe(CO)₅ and CF₃COOH/(CF₃CO)₂O in DMF, reacts with dioxygen at room temperature to give two μ₃-oxo compounds, namely, [Fe₃(μ₃-O)(CF₃COO)₆(DMF)₃], <b>3</b>, a Fe^(II)−Fe^(III)−Fe^(III) derivative, and [Fe₄(μ₃-O)₂(μ₂-CF₃COO)₆(CF₃COO)₂(DMF)₄], <b>4</b>, containing Fe(III) atoms only, which have been characterized by X-ray diffraction methods. …”

Small networks of cortical neurons change from irregular, tonic-like firing in W to rhythmic, ON/OFF burst-like activity in NREMS. by Kaoru Ohyama (8911646)

“…For ON to OFF transitions firing before transition was 2.5±0.29 Hz decreasing to 0.98±0.09 after the transition (N = 253 transitions, p<0.01, t = 6.53, paired Student's t-test). …”

Rapamycin prevented death from renal dysfunction in <i>Tsc2</i>^{Δ<i>podocyte</i>}. by Wakiko Iwata (8600457)

“…<p>(<b>A</b>) <i>Tsc2</i>^{Δ<i>podocyte</i>} mice treated with rapamycin had improved survival compared to vehicle-treated <i>Tsc2</i>^{Δ<i>podocyte</i>} mice. …”

<i>B. bassiana</i>-induced cell loss requires Wek, but Wek has pleiotropic functions. by Deepanshu N. D. Singh (20721878)

“…The data underlying panels C, E, G, I and J can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003020#pbio.3003020.s011" target="_blank">S5 Table</a> Source data.…”

Table 1_Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks.docx by Chen Shaopeng (20576303)

“…</p>Methods<p>In this study, five adult male Tianzhu white yaks (4.5 years old) were selected and fed under the same nutritional conditions. …”

Sperm motility is altered in <i>Cfap97d1</i>^{<i>KOMP-/-</i>} mice. by Seiya Oura (9234312)

“…<p><b>(A)</b> Curvilinear velocity (VCL) and <b>(B)</b> average path velocity (VAP) values were reduced in <i>Cfap97d1</i>^{<i>KOMP-/-</i>} sperm. …”

Anticancer Effects of 1,3-Dihydroxy-2-Methylanthraquinone and the Ethyl Acetate Fraction of <i>Hedyotis Diffusa</i> Willd against HepG2 Carcinoma Cells Mediated <i>via</i> Apoptosi... by Yun-lan Li (2606119)

“…<div><p><i>Hedyotis Diffusa</i> Willd, used in Traditional Chinese Medicine, is a treatment for various diseases including cancer, owing to its mild effectiveness and low toxicity. …”

ApoE deficiency leads to impaired dendritic development of injury-induced adult-born granule neurons. by Yacine Tensaouti (8520171)

“…<p>(<b>A</b>) ApoE deficiency did not affect the distance to the first dendritic branching but did significantly affect dendritic complexity (<b>B</b>) in the iGCL (p < 0.001), oGCL (p < 0.01) and contralateral (p < 0.01) dentate gyrus when compared to WT. …”

Proposed model for extracellular/intracellular Gal-9 <i>trans</i> and <i>cis</i> association with Tim-3 in regulation of monocyte inflammatory cytokine expressions through TLR sign... by Cheng J. Ma (219544)

“…Intracellular Gal-9 also inhibits STAT3 but not STAT-1 phosphorylation, leading to increased IL-12 and decreased IL-23 gene transcriptions. However, intracellular Gal-9 appears to reduce Tim-3 cell surface expression by two distinct mechanisms: <i>cis</i> association/internalization and transcriptional inhibition, through a STAT-3-independent but possibly T-bet-dependent pathway (10). …”

Model coefficient estimates predict change in psychophysical pain evaluation given HFA. by Rose M. Caston (11815157)

“…The coefficient for the SFG decreased over time. Although many regions had low coefficients (0.1), none were negative, which means increased HFA is linked to increased pain ratings. …”

Analysing mHealth usage logs in RCTs: Explaining participants’ interactions with type 2 diabetes self-management tools by Meghan Bradway (5703473)

“…HbA1c was collected (baseline, 4- and 12-months). Usage logs were categorized into registrations or navigations.…”

Schematic representation of the distribution of group I introns, according to their Pcl (row) and to the species harboring them (column). by Cyril Férandon (236997)

“…All introns of the same Pcl are in the same row and all introns carried by a given species are in the same column. The first 35 Pcls were named by increasing alphabetic characters from the 5′-end of the <i>cox1</i> CDS. …”