Mutation of acetylated lysine residues results in mislocalization of NDPK-D. by Yuki Fujita (330873)

“…Acetylation levels were determined as described in (A). Replacement of lysine residues with arginine decreased acetylation levels. n = 3. …”

Functional interpretation of direct and indirect consequences of miR-124 loss. by Kailiang Sun (184403)

“…Amongst motifs associated with decreased gene expression in <i>mir-124</i> mutants, the top motif corresponds to the Pumilio site; others motifs include the seeds of K box family miRNAs, miR-10-5p, and an orphan motif (AUGCAAA) with several hundred conserved matches (defined by TargetScan). …”

Table1_Novel Insight Into the Role of ACSL1 Gene in Milk Production Traits in Buffalo.docx by Yuxin Lin (4042208)

“…<p>Understanding the genetic mechanisms underlying milk production traits contribute to improving the production potential of dairy animals. Long-chain acyl-CoA synthetase 1 (ACSL1) plays a key role in fatty acid metabolism and was highly expressed in the lactating mammary gland epithelial cells (MGECs). …”

DataSheet_1_Molecular Surveillance and Ex Vivo Drug Susceptibilities of Plasmodium vivax Isolates From the China–Myanmar Border.docx by Weilin Zeng (279835)

“…<p>Drug resistance in Plasmodium vivax may pose a challenge to malaria elimination. Previous studies have found that P. vivax has a decreased sensitivity to antimalarial drugs in some areas of the Greater Mekong Sub-region. …”

Supplementary file 1_Mechanical properties of 3D voxel-printed materials for cardiovascular tissue imitation.docx by Joël Illi (21449474)

“…</p>Results<p>In the first step, varying the strand density, the tested samples showed a 0%–60% strain modulus of elasticity of 0.215–0.278 N/mm², representing a 4–5-fold reduction in elastic modulus compared to that of the base material, Agilus30 Clear. …”

Table 1_Redox status of biomarkers in serum of dogs with hypothyroidism and its treatment with levothyroxine sodium.docx by Ling Zhu (56356)

“…Following 45-day treatment with levothyroxine sodium (0.02 mg/kg orally twice daily), antioxidant parameters improved progressively: SOD increased from 60.2 to 76.7 U/mL (Day 0-14) and further to 83.3 U/mL (Day 45); CAT from 105.9 to 115.5 mU/mL (Day 0-14) reaching 132.9 mU/mL (Day 45); GSH-Px from 10.2 to 8.4 U/mL (Day 0-14) then 9.7 U/mL (Day 45), while MDA decreased from 8.2→6.8→4.4 μmol/L correspondingly. …”

Table 2_Redox status of biomarkers in serum of dogs with hypothyroidism and its treatment with levothyroxine sodium.docx by Ling Zhu (56356)

“…Following 45-day treatment with levothyroxine sodium (0.02 mg/kg orally twice daily), antioxidant parameters improved progressively: SOD increased from 60.2 to 76.7 U/mL (Day 0-14) and further to 83.3 U/mL (Day 45); CAT from 105.9 to 115.5 mU/mL (Day 0-14) reaching 132.9 mU/mL (Day 45); GSH-Px from 10.2 to 8.4 U/mL (Day 0-14) then 9.7 U/mL (Day 45), while MDA decreased from 8.2→6.8→4.4 μmol/L correspondingly. …”

Supplementary Material for: Time-Restricted Feeding Restored Insulin-Growth Hormone Balance and Improved Substrate and Energy Metabolism in MC4RKO Obese Mice by Wang W. (2888099)

“…<b><i>Results:</i></b> TRF increased pulsatile GH secretion in dark phase and suppressed hyperinsulinemia in MC4RKO obese mice to reach a reduced insulin/GH ratio. This was accompanied by the improvement in insulin sensitivity, metabolic flexibility, glucose tolerance, and decreased glucose fluctuation, together with appropriate modification of gene expression involved in substrate metabolism and adipose tissue browning. …”

Tumor uptake of the affibody molecules by subcutaneous xenografts. by Shanli Zhu (3504548)

“…The unselected original affibody scaffold molecule Z_WT with no binding affinity to LMP-2 served as a control. The fluorescence signal in xenografts were detectable at 0.5 h post-injection. …”

Neuromodulation with low-intensity pulsed ultrasound (Lipus) combined with curcumin-gold nanoparticles (Cur-AuNPs) in an Alzheimer's disease model by Laura de Roch Casagrande (22672470)

“…This is the first study to evaluate the synergistic effects of LIPUS and CUR-AuNPs in an AD model, which aimed to investigate the effects of these therapies on learning, memory and neuroinflammation in mice with <i>β</i>-amyloid peptide (βA1−42)-induced AD. Sixty mice were divided into five groups: control, βA1−42, βA1−42 + LIPUS, βA1−42 + CUR-AuNPs, and βA1−42 + LIPUS + CUR-AuNPs. …”

Supplementary Figure 6 from <i>ALK</i> Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma by Anne-Florence Blandin (15056366)

“…ds=cortex-dev) shows that ALK positive cells make up less than 1% of all cells in the dataset and aren't localized within a specific cluster.B. Cluster-level summary of the human scRNA dataset shows that ALK expression (TPM) is decreased compared to EGFR, NTRK2, and NTRK3, and ALK positive cells make up a much lower percentage of each cluster compared to those 3 genes.C. 2D representation of developmental mouse forebrain (E12.5 – P6) in a single cell RNA-seq atlas (http://cc-shiny-01.functionalgenomics.ca/braindex/clusters) shows similar results as seen in the human scRNA Nowakowski dataset.D. …”

Supplementary Figure 6 from <i>ALK</i> Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma by Anne-Florence Blandin (15056366)

“…ds=cortex-dev) shows that ALK positive cells make up less than 1% of all cells in the dataset and aren't localized within a specific cluster.B. Cluster-level summary of the human scRNA dataset shows that ALK expression (TPM) is decreased compared to EGFR, NTRK2, and NTRK3, and ALK positive cells make up a much lower percentage of each cluster compared to those 3 genes.C. 2D representation of developmental mouse forebrain (E12.5 – P6) in a single cell RNA-seq atlas (http://cc-shiny-01.functionalgenomics.ca/braindex/clusters) shows similar results as seen in the human scRNA Nowakowski dataset.D. …”

DataSheet3_Effects of Huang-Lian-Jie-Du decoction on improving skin barrier function and modulating T helper cell differentiation in 1-chloro-2,4-dinitrobenzene-induced atopic derm... by Huiyuan Zhang (66646)

“…</p><p>Results: HLJDD showcased a substantial amelioration in skin through the upregulation of FLG, LOR, AQP3, and reducing scratching behaviors in AD-like mice, Also, the quantity of infiltrated mast cells (MCs), pruritus-related mRNA were decreased. …”

DataSheet1_Effects of Huang-Lian-Jie-Du decoction on improving skin barrier function and modulating T helper cell differentiation in 1-chloro-2,4-dinitrobenzene-induced atopic derm... by Huiyuan Zhang (66646)

“…</p><p>Results: HLJDD showcased a substantial amelioration in skin through the upregulation of FLG, LOR, AQP3, and reducing scratching behaviors in AD-like mice, Also, the quantity of infiltrated mast cells (MCs), pruritus-related mRNA were decreased. …”

DataSheet2_Effects of Huang-Lian-Jie-Du decoction on improving skin barrier function and modulating T helper cell differentiation in 1-chloro-2,4-dinitrobenzene-induced atopic derm... by Huiyuan Zhang (66646)

“…</p><p>Results: HLJDD showcased a substantial amelioration in skin through the upregulation of FLG, LOR, AQP3, and reducing scratching behaviors in AD-like mice, Also, the quantity of infiltrated mast cells (MCs), pruritus-related mRNA were decreased. …”

Cort expression leads to proteasome-mediated degradation of Mtrm in cell culture. by Zachary J. Whitfield (453399)

“…Only wild-type Cort leads to decreased levels of tagged Mtrm protein. The <i>RH65</i> mutation results in a premature stop codon in Cort. …”

Machine learning-based management of electric vehicles charging: Towards highly-dispersed fast chargers by Shibl, M.

“…Additionally, LSTM was also the model with the smallest error rate, at a value of ±0.7%, followed by RF, DT, KNN, SVM, DNN, and NB. …”
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Ratings of perceived exertion misclassify intensities for sedentary older adults during graded cycling test: Effect of supramaximal high-intensity interval training by Jabbour G.

“…Two healthy groups of 17 young adults [average (SD) age: 26.2 (2.4) year] and 13 older adults [average (SD) age: 54.5 (2.3) year] completed a 6-week SCE intervention on an ergocycle. …”
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Image3_Modulation of the biological network of lumbar spinal stenosis by Tongdu Huoxue Decoction based on clinical metabolomics.TIF by Luhong Ji (14819746)

“…Regarding metabolomics, the levels of 41 differential metabolites were significantly different in the normal group (group NC) compared to group A, and those were significantly restored after treatment with THD, including chenodeoxycholic acid 3-sulfate, taurohyodeoxycholic acid, 3,5-Dihydroxy-4-methoxybenzoic acid, pinocembrin. …”

Table_3_Transcriptional changes in the gilthead seabream (Sparus aurata) skin in response to ultraviolet B radiation exposure.xlsx by Ricardo N. Alves (8839895)

“…S. aurata juveniles were exposed for 43 days to two experimental groups: 1) UVB (daily dose, 6 kJ m^-2; representing levels between 5 and 7 m depth); 2) Unirradiated treatment, used as a control. …”