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99541
Data Sheet 7_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo...
Published 2024“…</p>Results<p>The results show that compound 16C has low toxicity (LD<sub>50</sub> > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T<sub>1/2kel</sub>) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”
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99542
Visualization Study of Methane Deflagration Characteristics in Variable Diameter Pipelines Based on Schlieren Technique
Published 2024“…Under four experimental conditions of variable cross-sectional area ratio (<i>VR</i>) of 1.0, 0.6, 0.4, and 0.2, the schlieren images of the deflagration process of methane/air premixed gas with a methane concentration of 9.5% were captured by a high-speed camera. …”
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99543
Statistical analysis results.
Published 2023“…Average cell size increases at higher temperatures, likely resulting from cell cycle arrest, whereas chlorophyll fluorescence decreased, especially in 4 h, indicating a photoacclimation response. …”
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99544
Data Sheet 8_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo...
Published 2024“…</p>Results<p>The results show that compound 16C has low toxicity (LD<sub>50</sub> > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T<sub>1/2kel</sub>) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”
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99545
Image_2_Regulation of Myofilament Contractile Function in Human Donor and Failing Hearts.JPEG
Published 2020“…Permeabilized cardiac myocyte preparations were attached between a force transducer and a position motor, and both the Ca<sup>2+</sup> dependence and sarcomere length (SL) dependence of force, rate of force, loaded shortening, and power output were measured at 15 ± 1°C. …”
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99546
Image_1_Regulation of Myofilament Contractile Function in Human Donor and Failing Hearts.JPEG
Published 2020“…Permeabilized cardiac myocyte preparations were attached between a force transducer and a position motor, and both the Ca<sup>2+</sup> dependence and sarcomere length (SL) dependence of force, rate of force, loaded shortening, and power output were measured at 15 ± 1°C. …”
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99547
Image_8_Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation.jpeg
Published 2024“…., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. …”
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99548
Image_11_Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation.tif
Published 2024“…., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. …”
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99549
Data_Sheet_1_Trends in the Prevalence and Antibiotic Resistance of Non-tuberculous Mycobacteria in Mainland China, 2000–2019: Systematic Review and Meta-Analysis.PDF
Published 2020“…</p><p>Conclusions: The prevalence of NTM in China has shown a decreasing trend. M. abscessus was replaced as the dominant species by Mycobacterium intracellulare over the course of the study. …”
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99550
Table_2_Time-restricted feeding affects colonic nutrient substrates and modulates the diurnal fluctuation of microbiota in pigs.xlsx
Published 2023“…</p>Results<p>Results showed that TRF altered the distribution of feed intake without changing the total feed intake within a day (p = 0.870). TRF decreased the overall concentration of colonic cellulose and altered their oscillating patterns. …”
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99551
Data Sheet 4_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo...
Published 2024“…</p>Results<p>The results show that compound 16C has low toxicity (LD<sub>50</sub> > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T<sub>1/2kel</sub>) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”
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99552
Table2_QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.XLSX
Published 2022“…QSYQ also inhibited the following: release of RP S19 from the injured myocardium, activation of C5a receptors in monocytes, polarization of macrophages, and release of TGF-β1. …”
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99553
Differential regulation of <i>FasL</i> promoter activities in human T cells and in human colon cancer cells.
Published 2013“…<p><b>A</b>). Effect of TBE mutations on <i>FasL</i> promoter activities in Jurkat T cells. …”
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99554
Table_1_Time-restricted feeding affects colonic nutrient substrates and modulates the diurnal fluctuation of microbiota in pigs.xlsx
Published 2023“…</p>Results<p>Results showed that TRF altered the distribution of feed intake without changing the total feed intake within a day (p = 0.870). TRF decreased the overall concentration of colonic cellulose and altered their oscillating patterns. …”
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99555
Data Sheet 9_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo...
Published 2024“…</p>Results<p>The results show that compound 16C has low toxicity (LD<sub>50</sub> > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T<sub>1/2kel</sub>) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”
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99556
Image_3_Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation.jpeg
Published 2024“…., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. …”
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99557
Data_Sheet_1_Amino acid intake with protein food source and incident dyslipidemia in Korean adults from the Ansan and Ansung Study and the Health Examinee Study.docx
Published 2023“…Compared to the lowest quartile group, the highest quartile groups of essential amino acid intake [men: hazard ratio (HR) = 0.78; 95% confidence interval (CI), 0.63–0.97; P for trend = 0.0088; women: HR = 0.86; 95% CI, 0.76–0.99; P for trend = 0.0201] and nonessential amino acid intake (men: HR = 0.75; 95% CI, 0.60–0.94; P for trend = 0.0069; women: HR = 0.81; 95% CI, 0.71–0.93; P for trend = 0.0024) had a decreased risk of dyslipidemia. Plant-based protein intake had a negative association and animal-based protein intake had a nonsignificant association with dyslipidemia after adjustment for energy-adjusted fat intake. …”
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99558
Table_4_Sperm DNA Hypomethylation Proximal to Reproduction Pathway Genes in Maturing Elite Norwegian Red Bulls.XLSX
Published 2020“…Most of the identified DMRs (69%) exhibited a less than 10% methylation difference while only 1.5% of DMRs exceeded a 25% methylation difference. …”
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99559
Data Sheet 6_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo...
Published 2024“…</p>Results<p>The results show that compound 16C has low toxicity (LD<sub>50</sub> > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T<sub>1/2kel</sub>) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”
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99560
Image_12_Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation.tif
Published 2024“…., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. …”