Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

SNX5 phosphorylation sites. by Nao Itai (5954666)

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Effects of Cu (5 µM) pretreatment on Hcy-induced decrease in cell viability and LDH release. by Daoyin Dong (424519)

Three variants lower the rheobase and increase firing frequency of Ca_V3.3, while the A398V variant shows the opposite effect. by Yousra El Ghaleb (22075892)

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TG6-44 treatment decreases A/X31-induced ROS in THP-1 cells. by Juan A. De La Cruz (11154187)

The role of AGEs in high glucose-induced voltage-gated K⁺ (K_v) channels dysfunction in vascular smooth muscle cells (VSMCs). by Wen Su (332346)

“…B: I-V relationships of K_v current density in VSMCs. …”

Changes in Prevalence of HIV or Syphilis among Male Sex Workers and Non-Commercial Men Who Have Sex with Men in Shenzhen, China: Results of a Second Survey by Yuanwei Huang (3390809)

“…Decreased syphilis rates were observed in both MSWs (12.9% in 2008 vs 4.5% in 2014, P<0.001) and ncMSM (20.2% in 2008 vs 17.4% in 2014, P = 0.221).…”

S1 Data - by Kadio Jean-Jacques Olivier Kadio (15503159)

“…In an adjusted analysis, the hazards of LTFU were higher among men compared to women (aHR = 1.10; 95%CI 1.08–1.12), being aged 13–25 years old versus older patients (aHR = 1.07; 95%CI = 1.03–1.13), and among those initating ART in smaller health facilities (aHR = 1.52; 95%CI 1.45–1.60). …”

Participant characteristics. by Kadio Jean-Jacques Olivier Kadio (15503159)

“…In an adjusted analysis, the hazards of LTFU were higher among men compared to women (aHR = 1.10; 95%CI 1.08–1.12), being aged 13–25 years old versus older patients (aHR = 1.07; 95%CI = 1.03–1.13), and among those initating ART in smaller health facilities (aHR = 1.52; 95%CI 1.45–1.60). …”

A conceptual framework of piecewise LGCMs for changes in EQ-5D-5L measures following RT. by Somayeh Momenyan (10111603)

Pathways illustrating the network of genomic loci involved with (A & B) Regions undergoing increase in 5mC content and (C & D) decrease in 5mC contents, upon simulated microgravity. by Basudev Chowdhury (2182760)

“…<p>Pathways illustrating the network of genomic loci involved with (A & B) Regions undergoing increase in 5mC content and (C & D) decrease in 5mC contents, upon simulated microgravity.…”

Eight hours of 10% CSE leads to a decrease in wild-type AQP5 but no change in N228K AQP5 (n = 3; * p<0.05 with ANOVA one-way). by Nadia N. Hansel (359186)

“…<p>Eight hours of 10% CSE leads to a decrease in wild-type AQP5 but no change in N228K AQP5 (n = 3; * p<0.05 with ANOVA one-way).…”

S100A9 treatment decreases the secretion of pro-inflammatory cytokines (A) 5 days after LPS injection, sera were collected and tested for IL-6 by ELISA. by Annabelle Cesaro (112070)

DataSheet1_A Non-Synonymous Point Mutation in a WD-40 Domain Repeat of EML5 Leads to Decreased Bovine Sperm Quality and Fertility.docx by Eriklis Nogueira (7475576)

A mutation in <i>dSK</i> results in decreased long-term memory 24 h after 5 h ‘extended’ training session. by Ahmad N. Abou Tayoun (326696)

Revisiting the sealed heating method–V158411 decreases Chk1 nuclear immunofluorescence in HT29 cells heated in a low well volume. by Andrew J. Massey (239469)

The AMPK inhibitor CC exacerbates palmitate-induced decreases in viability. by Dustin M. Lee (8207457)

AQP2 and p-AQP2 IMCD localization. by Sophie Constantin Lütken (689916)

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AQP1 abundance. by Sophie Constantin Lütken (689916)

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