Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Characterization of the optimized nanoparticles (These values are means of a minimum of 5 batches). by Anjuman Arora (750291)

Infection of B6 mice with wild type <i>B</i>. <i>hermsii</i> and <i>Bh</i>Δ<i>dam</i> at decreasing infectious doses of approximately 1 x 10⁵ to 10 spirochetes. by Allison E. James (2794606)

This is the raw data of Immunofluorescence in Met-5A cell. by Yangyang Yin (14323701)

Subjects:

In we present the number of modules determined by DMSP on various values of connectivity density by Ioannis A Maraziotis (86282)

“…When we apply stricter criteria (as in red dotted line) there is a slight decrease in the number of the modules but at the same time the connectivity density values are better. …”

Decrease in salivary TTV titer (log₁₀ titer/ml) in individuals positive for SARS-CoV-2 as a function of time from symptom onset. by Maria C. Mendes-Correa (11326465)

Data_Sheet_1_Can multi-cropping affect soil microbial stoichiometry and functional diversity, decreasing potential soil-borne pathogens? A study on European organic vegetable cropp... by Alessandra Trinchera (10984554)

Overexpression of ATX delays retinal vascularization and decreases vessel branching. by Hiroshi Yukiura (741223)

Decreased odor-evoked OSNs activity leads to an elevated level of TRPM5 mRNA. by Arisa Oshimoto (403221)

Decreased by Violet R. Mukaro (282939)

Decrease of NF-κB activity in tumor tissue of CCR5^−/− mice. by Ju Kyoung Song (324058)

“…<p><b>A</b>, The DNA binding activity of NF-κB was determined in the nuclear extracts of the CCR5^−/− mice and CCR5^+/+ mice tumor tissues by EMSA described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033747#s4" target="_blank">material and methods</a>. …”

The decrease of ULK1 expression by miR-17-5p from BCG infection. by Xiangguo Duan (423329)

Cytokine dependent decrease in vSMC viability after type I NKT cell activation. by Gijs H. M. van Puijvelde (500345)

Table_5_Elevated Seawater Temperatures Decrease Microbial Diversity in the Gut of Mytilus coruscus.XLSX by Yi-Feng Li (433967)

HFA decreased expression of osteoclastic markers in alveolar bone. by Mani Alikhani (5180768)

Increasing temperature decreases oxygen concentration and decreasing oxygen content decreases neuronal excitability. by Yuguo Yu (172221)

“…Increasing temperature can dramatically decrease oxygen levels. B. Response of layer 2/3 pyramidal cells (n = 5) to the intracellular injection of a depolarizing current pulse (200 pA, 500 ms) at different temperatures (same experiments as in A). …”

Dispersion-temperature of microgels decreases at lower pHs. by Chi-Shuo Chen (234719)

“…<p>As pH is reduced from 8.0 (black) to 7.7 (blue) to 7.5 (red) to 7.3 (green), non-linear microgel dispersion-temperature changes were observed while pH decreases. …”

Vacuolar dynamics after a rapid temperature decrease. by Noriaki Kadohama (382080)

“…<p>Vacuolar membrane labeled with FM1-43 (green) and chlorophyll fluorescence (magenta) in palisade mesophyll cells of saintpaulia leaf were observed before (A) and 10 min after (B) a rapid temperature decrease from 25°C to 5°C and kept at 5°C for 1 min. …”

Imiquimod decreases DFTD cell number in culture in a concentration and time dependent manner. by Amanda L. Patchett (3391931)

Mycolactone induces a decrease in dermal collagen fibers. by José B. Gama (296675)