Image_2_PiggyBac Transposon-Mediated CD19 Chimeric Antigen Receptor-T Cells Derived From CD45RA-Positive Peripheral Blood Mononuclear Cells Possess Potent and Sustained Antileukemi... by Masaya Suematsu (12006506)

“…We previously reported that piggyBac (PB) transposon-mediated CD19 CAR-T cells exhibit a memory-rich phenotype that is characterized by the high proportion of CD45RA⁺/C-C chemokine receptor type 7 (CCR7)⁺ T-cell fraction. …”

Tapered Multiblock Copolymers Based on Farnesene and Styrene: Impact of Biobased Polydiene Architectures on Material Properties by Christian Wahlen (1768180)

“…The one-pot, tapered copolymer approach was used to synthesize series of tri- (ABA) and pentablock (ABABA) copolymers of styrene (A) and β-farnesene (B), varying the polydiene volume fraction between 0.50 and 0.68, respectively. …”

Image_5_PiggyBac Transposon-Mediated CD19 Chimeric Antigen Receptor-T Cells Derived From CD45RA-Positive Peripheral Blood Mononuclear Cells Possess Potent and Sustained Antileukemi... by Masaya Suematsu (12006506)

“…We previously reported that piggyBac (PB) transposon-mediated CD19 CAR-T cells exhibit a memory-rich phenotype that is characterized by the high proportion of CD45RA⁺/C-C chemokine receptor type 7 (CCR7)⁺ T-cell fraction. …”

Image_7_PiggyBac Transposon-Mediated CD19 Chimeric Antigen Receptor-T Cells Derived From CD45RA-Positive Peripheral Blood Mononuclear Cells Possess Potent and Sustained Antileukemi... by Masaya Suematsu (12006506)

“…We previously reported that piggyBac (PB) transposon-mediated CD19 CAR-T cells exhibit a memory-rich phenotype that is characterized by the high proportion of CD45RA⁺/C-C chemokine receptor type 7 (CCR7)⁺ T-cell fraction. …”

Meta data of <i>In vitro</i> and <i>In vivo</i> experiments. by Mohammad Abdullah Taher (18691717)

“…The extract showed broad-spectrum antibacterial activity, with strongest inhibition against <i>Pseudomonas aeruginosa</i> (19 mm) and <i>Salmonella typhi</i> (19 mm), though 30–50% less potent than standard antibiotics. In antidiarrheal testing, 400 mg/kg dose reduced diarrheal episodes by 58.06% compared to control, while in analgesic assay it decreased writhing by 59.18%. …”

ENPP1 Affects Insulin Action and Secretion: Evidences from <em>In Vitro</em> Studies by Rosa Di Paola (158545)

“…<div><p>The aim of this study was to deeper investigate the mechanisms through which ENPP1, a negative modulator of insulin receptor (IR) activation, plays a role on insulin signaling, insulin secretion and eventually glucose metabolism. …”

CdpR directly binds to <i>pqsH-cdpR</i> intergenic region and regulates <i>pqsH</i> expression. by Jingru Zhao (2633782)

“…<b>(F)</b> The production of PQS was decreased in the <i>cdpR</i> mutant. Lane 1 contains 50 ng of PQS. …”

Table_1_BCR-ABL1 Doubling-Times and Halving-Times May Predict CML Response to Tyrosine Kinase Inhibitors.pdf by Maria Stella Pennisi (6371525)

“…Thus, we retrospectively examined BCR-ABL1 evolution in 305 chronic-phase CML patients receiving imatinib mesylate (IM) as a first line treatment. Patients were subdivided in two groups: those with a confirmed rise in BCR-ABL1 transcripts without MR^3.0 loss and those failing IM. …”

The core model with an additional intracellular feedback is superior and gene expression upon downregulation of IRF family members. by Katharina Robichon (8445099)

“…(<b>H</b>) Gene expression upon decreased <i>IRF8</i> expression. Huh7.5 cells were incubated with 50 nM siRNA directed against <i>IRF8</i> (red), against <i>IRF8</i> and <i>IRF2</i> (lilac) or non-targeting control (blue) for 24 hours, and then treated with 500 U/ml IFNα. …”

Image_1_PiggyBac Transposon-Mediated CD19 Chimeric Antigen Receptor-T Cells Derived From CD45RA-Positive Peripheral Blood Mononuclear Cells Possess Potent and Sustained Antileukemi... by Masaya Suematsu (12006506)

“…We previously reported that piggyBac (PB) transposon-mediated CD19 CAR-T cells exhibit a memory-rich phenotype that is characterized by the high proportion of CD45RA⁺/C-C chemokine receptor type 7 (CCR7)⁺ T-cell fraction. …”

Data_Sheet_1_Increased fruit intake is associated with reduced risk of depression: evidence from cross-sectional and Mendelian randomization analyses.docx by Zhaoqi Yan (11322876)

“…Fruit intake was also associated with a decreased risk of neuroticism traits related to depression, including feeling lonely (OR = 0.82, 95% CI = 0.74–0.90; p = 2.91E-05), feeling miserable (OR = 0.79, 95% CI = 0.72–0.87; p = 2.35E-06), feeling fed-up (OR = 0.75, 95% CI = 0.68–0.83; p = 2.78E-08), irritable mood (OR = 0.89, 95% CI = 0.79–0.99; p = 0.03), and neuroticism (OR = 0.85, 95% CI = 0.76–0.96; p = 9.94E-03). …”

Image_6_PiggyBac Transposon-Mediated CD19 Chimeric Antigen Receptor-T Cells Derived From CD45RA-Positive Peripheral Blood Mononuclear Cells Possess Potent and Sustained Antileukemi... by Masaya Suematsu (12006506)

“…We previously reported that piggyBac (PB) transposon-mediated CD19 CAR-T cells exhibit a memory-rich phenotype that is characterized by the high proportion of CD45RA⁺/C-C chemokine receptor type 7 (CCR7)⁺ T-cell fraction. …”

Image_3_PiggyBac Transposon-Mediated CD19 Chimeric Antigen Receptor-T Cells Derived From CD45RA-Positive Peripheral Blood Mononuclear Cells Possess Potent and Sustained Antileukemi... by Masaya Suematsu (12006506)

“…We previously reported that piggyBac (PB) transposon-mediated CD19 CAR-T cells exhibit a memory-rich phenotype that is characterized by the high proportion of CD45RA⁺/C-C chemokine receptor type 7 (CCR7)⁺ T-cell fraction. …”

Data_Sheet_1_BCR-ABL1 Doubling-Times and Halving-Times May Predict CML Response to Tyrosine Kinase Inhibitors.PDF by Maria Stella Pennisi (6371525)

“…Thus, we retrospectively examined BCR-ABL1 evolution in 305 chronic-phase CML patients receiving imatinib mesylate (IM) as a first line treatment. Patients were subdivided in two groups: those with a confirmed rise in BCR-ABL1 transcripts without MR^3.0 loss and those failing IM. …”

Gender-Specific Effects of Genetic Variants within Th1 and Th17 Cell-Mediated Immune Response Genes on the Risk of Developing Rheumatoid Arthritis by Rafael Cáliz (452151)

“…Carriers of <i>Dectin-2</i>_rs4264222T allele had an increased risk of RA (OR = 1.47, 95%CI 1.10–1.96) whereas patients harboring the <i>DC-SIGN</i>_rs4804803G, <i>MCP-1</i>_rs1024611G, <i>MCP-1</i>_rs13900T and <i>MCP-1</i>_rs4586C alleles had a decreased risk of developing the disease (OR = 0.66, 95%CI 0.49–0.88; OR = 0.66, 95%CI 0.50–0.89; OR = 0.73, 95%CI 0.55–0.97 and OR = 0.68, 95%CI 0.51–0.91). …”

Expression of RIO kinases is associated with EGFR and Akt activity in GBM cells. by Renee D. Read (268044)

“…(G) Neurosphere cultures treated for 24 hours with DMSO or indicated inhibitors. P110 inhibitors: 50 µM LY294002, 1 µM BEZ-235, 2 µM GDC-0941 <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003253#pgen.1003253-Raynaud1" target="_blank">[71]</a>, 2 µM PI-103 <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003253#pgen.1003253-Raynaud1" target="_blank">[71]</a>. …”

Plasma MicroRNAs as Potential Noninvasive Biomarkers for In-Stent Restenosis by Meijiao He (666387)

“…</p><p>Methods</p><p>This retrospective, observational single-centre study was conducted at the cardiovascular department of a tertiary hospital centre in the north of China. …”

DataSheet_1_Transcriptome analysis reveals that auxin promotes strigolactone-induced adventitious root growth in the hypocotyl of melon seedlings.pdf by Jingrui Li (1546318)

“…Compared to that in the control, the ABA content decreased by 10.30%–11.83% in the GR24 treatment group and decreased by 18.78%-24.00% in the GR24+IAA treatment group at 6–10 days.…”

Enhanced drug resistance suppression by serum-stable micelles from multi-arm amphiphilic block copolymers and tocopheryl polyethylene glycol 1000 succinate by Lei He (143930)

“…<p><b>Aim:</b> To develop a robust drug-delivery system using multi-arm amphiphilic block copolymers for enhanced efficacy in cancer therapy.…”

Data_Sheet_1_MicroRNA29B induces fetal hemoglobin via inhibition of the HBG repressor protein MYB in vitro and in humanized sickle cell mice.docx by Qingqing Gu (338902)

“…</p>Materials and methods<p>Human KU812 were cultured and normal CD34 cells (n = 3) were differentiated using a two-phase erythropoiesis culturing system and transfected with MIR29B (50 and 100 nM) mimic or Scrambled (Scr) control in vitro. …”