Image_1_Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation.tif by Kaixiang Xu (4571833)

“…Here, we generated the GGTA1, B2M, and CIITA (GBC) triple-gene-modified Diannan miniature pigs, analyzed the transcriptome of GBC-modified peripheral blood mononuclear cells (PBMCs) in the pig's spleen, and investigated their effectiveness in anti-immunological rejection. A total of six cloned piglets were successfully generated using somatic cell nuclear transfer, one of them carrying the heterozygous mutations in triple genes and the other five piglets carrying the homozygous mutations in GGTA1 and CIITA genes, but have the heterozygous mutation in the B2M gene. …”

Table_1_Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation.docx by Kaixiang Xu (4571833)

“…Here, we generated the GGTA1, B2M, and CIITA (GBC) triple-gene-modified Diannan miniature pigs, analyzed the transcriptome of GBC-modified peripheral blood mononuclear cells (PBMCs) in the pig's spleen, and investigated their effectiveness in anti-immunological rejection. A total of six cloned piglets were successfully generated using somatic cell nuclear transfer, one of them carrying the heterozygous mutations in triple genes and the other five piglets carrying the homozygous mutations in GGTA1 and CIITA genes, but have the heterozygous mutation in the B2M gene. …”

Table_2_Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation.docx by Kaixiang Xu (4571833)

“…Here, we generated the GGTA1, B2M, and CIITA (GBC) triple-gene-modified Diannan miniature pigs, analyzed the transcriptome of GBC-modified peripheral blood mononuclear cells (PBMCs) in the pig's spleen, and investigated their effectiveness in anti-immunological rejection. A total of six cloned piglets were successfully generated using somatic cell nuclear transfer, one of them carrying the heterozygous mutations in triple genes and the other five piglets carrying the homozygous mutations in GGTA1 and CIITA genes, but have the heterozygous mutation in the B2M gene. …”

Image_2_Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation.tif by Kaixiang Xu (4571833)

“…Here, we generated the GGTA1, B2M, and CIITA (GBC) triple-gene-modified Diannan miniature pigs, analyzed the transcriptome of GBC-modified peripheral blood mononuclear cells (PBMCs) in the pig's spleen, and investigated their effectiveness in anti-immunological rejection. A total of six cloned piglets were successfully generated using somatic cell nuclear transfer, one of them carrying the heterozygous mutations in triple genes and the other five piglets carrying the homozygous mutations in GGTA1 and CIITA genes, but have the heterozygous mutation in the B2M gene. …”

Data_Sheet_1_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.PDF by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_4_The gut microbiota correlate with the disease characteristics and immune status of patients with untreated diffuse large B-cell lymphoma.jpeg by Zhouning Lin (14648597)

“…</p>Results<p>The alpha-diversity index of intestinal microecology in DLBCL patients was not significantly different when compared with HCs (P>0.05), nonetheless beta-diversity was significantly decreased (P=0.001). p_Proteobacteria were dominant in DLBCL, while p_Bacteroidetes abundance was significantly decreased when compared with HCs (P<0.05). …”

Expression and significance of CEMIP and CYP11B2 in serum in women with foetal growth restriction by Yang Yue (286377)

presentation2_TRPM7 Induces Tumorigenesis and Stemness Through Notch Activation in Glioma.pptx by Jingwei Wan (9765332)

“…The Oncomine data revealed a significant increase in TRPM7 mRNA expression in anaplastic astrocytoma, diffuse astrocytoma, and GBM patients compared to that in normal brain tissues. …”

presentation1_TRPM7 Induces Tumorigenesis and Stemness Through Notch Activation in Glioma.pdf by Jingwei Wan (9765332)

“…The Oncomine data revealed a significant increase in TRPM7 mRNA expression in anaplastic astrocytoma, diffuse astrocytoma, and GBM patients compared to that in normal brain tissues. …”

Table_4_Network pharmacology reveals that Berberine may function against Alzheimer’s disease via the AKT signaling pathway.XLSX by Wei Wei (21173)

“…Akt1 mRNA expression levels were significantly decreased in AD mice and significantly increased after BBR treatment (p < 0.05). …”

Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes by Nivedita Hegdekar (6563744)

Image_7_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Table_3_Network pharmacology reveals that Berberine may function against Alzheimer’s disease via the AKT signaling pathway.XLSX by Wei Wei (21173)

“…Akt1 mRNA expression levels were significantly decreased in AD mice and significantly increased after BBR treatment (p < 0.05). …”

Table_1_Network pharmacology reveals that Berberine may function against Alzheimer’s disease via the AKT signaling pathway.XLSX by Wei Wei (21173)

“…Akt1 mRNA expression levels were significantly decreased in AD mice and significantly increased after BBR treatment (p < 0.05). …”

Image_1_The gut microbiota correlate with the disease characteristics and immune status of patients with untreated diffuse large B-cell lymphoma.jpeg by Zhouning Lin (14648597)

“…</p>Results<p>The alpha-diversity index of intestinal microecology in DLBCL patients was not significantly different when compared with HCs (P>0.05), nonetheless beta-diversity was significantly decreased (P=0.001). p_Proteobacteria were dominant in DLBCL, while p_Bacteroidetes abundance was significantly decreased when compared with HCs (P<0.05). …”

Image_1_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_6_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_9_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”

Image_3_The gut microbiota correlate with the disease characteristics and immune status of patients with untreated diffuse large B-cell lymphoma.jpeg by Zhouning Lin (14648597)

“…</p>Results<p>The alpha-diversity index of intestinal microecology in DLBCL patients was not significantly different when compared with HCs (P>0.05), nonetheless beta-diversity was significantly decreased (P=0.001). p_Proteobacteria were dominant in DLBCL, while p_Bacteroidetes abundance was significantly decreased when compared with HCs (P<0.05). …”

Image_2_Analysis of Epigenetic Age Predictors in Pain-Related Conditions.JPEG by Katarzyna Malgorzata Kwiatkowska (8950196)

“…Signs of premature aging have been associated with chronic pain, but few studies have investigated aging biomarkers in pain-related conditions. A set of DNA methylation (DNAm)-based estimates of age, called “epigenetic clocks,” has been proposed as biological measures of age-related adverse processes, morbidity, and mortality. …”