The Type 2 Diabetes Risk Allele of <i>TMEM154</i>-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes by Marie Neergaard Harder (232759)

“…Significant associations between <i>TMEM154</i>-rs6813195 and the beta cell measures insulinogenic index and disposition index and between <i>FAF1</i>-rs17106184 and 2-hour serum insulin levels were selected for further investigation in additional Danish studies and results were combined in meta-analyses including up to 6,486 Danes.</p><p>Results</p><p>We confirmed associations with type 2 diabetes for five of the seven SNPs (<i>TMEM154</i>-rs6813195, <i>FAF1</i>-rs17106184, <i>POU5F1/TCF19</i>-rs3130501, <i>ARL15</i>-rs702634 and <i>ABCB9/MPHOSPH9</i>-rs4275659). …”

Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation. by Kyle C. Kloepping (9928265)

“…<p>(A) A375 melanoma cells were treated with 0.5 μM, 1.0 μM, or 2.0 μM 5-, 10-, or 16-TPP for 1 h and analyzed for mitochondria membrane potential by the JC-1 method (* significant relative to control; p<0.05; n = 2 from 2 separate experiments; N = 4). …”

Additional behavioral patterns in the 5€, 100€, and 1000€ treatments. by Pablo Brañas-Garza (336425)

Treatment by AG1024 induces unpairing of adult worms and decrease of egg laying in a dose and time-dependent manner. by Mathieu Vanderstraete (154327)

DataSheet2_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.pdf by Sunil Veeravalli (5074115)

“…<p>We previously showed that Fmo5^−/− mice exhibit a lean phenotype and slower metabolic ageing. …”

DataSheet1_Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5−/− mice, decreases plasma cholesterol and epididymal fat deposition.PDF by Sunil Veeravalli (5074115)

“…<p>We previously showed that Fmo5^−/− mice exhibit a lean phenotype and slower metabolic ageing. …”

HDAC5 inhibitors reverse the decreased expression of GR induced by DEX in cultured prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

Data_Sheet_2_Mycovirus Fusarium oxysporum f. sp. dianthi Virus 1 Decreases the Colonizing Efficiency of Its Fungal Host.pdf by Almudena Torres-Trenas (6445943)

Data_Sheet_1_Mycovirus Fusarium oxysporum f. sp. dianthi Virus 1 Decreases the Colonizing Efficiency of Its Fungal Host.docx by Almudena Torres-Trenas (6445943)

VEGFR2/VEGF-A ligand binding decreased ranibizumab and aflibercept mediated CCL2, CCL5, and CX3CL1 mRNA and protein levels in HCAECs. by Clare Arnott (2557705)

MAF1 protein expression is significantly decreased in luminal, HER2-positive, and TNBC breast cancer subtypes. by Stephanie Cabarcas-Petroski (9631636)

Class-specific mean decrease in accuracy (MDA) for directed motion and normal-, anomalous- and confined-diffusion. by Thorsten Wagner (1320081)

Decrease in cell migration and adhesion of MCF10A cells after knockdown of <i>MYO1C</i>. by Kittichate Visuttijai (3204519)

“…A dose-dependent decrease in relative cell index response to MYO1C depletion was observed reaching to a significant value with concentrations of 5 and 10 nM of <i>MYO1C</i>-siRNA at 48 hours post-transfection compared to control cells (mock transfection). …”

There is a significant decrease in fibroblast, α-SMA, and Ly6C staining accompanied with a decrease in proliferation, and increase in cell death in the outflow vein removed <i>Iex-... by Akshaar Brahmbhatt (551498)

“…</b> Pooled data from the semiquantitative analysis for intensity of Fsp-1 staining in the vessel wall of the outflow vein specimens removed from <i>Iex-1</i> KO and WT mice. There is a significant decrease in the mean Fsp-1 staining in the <i>Iex-1</i> KO animals when compared to WT controls (P<0.05). …”

– Decreasing rank differences in the comparison Wt-t0b vs Wt-t0a are plotted (in blue) against the rank of Wt-t0a and decreasing rank differences in the comparison Wt-t0a vs Wt-t0b... by Dietmar E Martin (5143)

A decrease in the invasiveness of <i>Candida albicans</i> into Caco-2 cells parallels the differentiation of intestinal epithelial cells. by Marianne Goyer (2550589)

“…The gene expression levels of Apolipoprotein A-IV (ΔΔCt) were statistically lower after 1, 2, 3 and 5 days post-seeding than at day 15 as a result of incomplete differentiation (*<i>p <</i> 0.05, Mann–Whitney test). …”

The Transition from a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk by Heba M Ismail (9568748)

“…Conclusions</p> <p>A transition from an increase to a decrease in AUC C-peptide approximately 1.5 years pre-diagnosis was validated in two independent cohorts. …”

Toca-1 recruitment around wild-type bacteria is associated with decreased recruitment of LC3 and autophagy markers. by Leigh A. Baxt (550378)

Fold decrease in virulence gene expression of <i>Salmonella in vivo</i> and <i>in vitro</i>^a. by Xiaojian Yang (295141)

“…Values represent down-regulation (fold-decrease) of gene expression.</p>#<p>Value for each gene represents a significant difference (<i>P</i><0.05) between the treatment and control samples in the <i>in vitro</i> experiment. …”

Developmental delay of <i>rpS13/+</i> animals is not due to a decrease in ribosome numbers or reduced translation rates. by Lisa Patricia Deliu (13570709)