Former Abusers of Anabolic Androgenic Steroids Exhibit Decreased Testosterone Levels and Hypogonadal Symptoms Years after Cessation: A Case-Control Study by Jon Jarløv Rasmussen (2993427)

“…</p><p>Methods</p><p>This study had a cross-sectional case-control design and involved 37 current AAS abusers, 33 former AAS abusers (mean (95%CI) elapsed duration since AAS cessation: 2.5 (1.7; 3.7) years) and 30 healthy control participants. …”

Decreased 11ß-HSD1 protein level by IGF-I overexpression <i>in vivo</i> and a direct treatment with IGF-I. by Subrata Chowdhury (787208)

“…<p><b>A</b>. IGF-I overexpression decreased the levels of 11ß-HSD1 in pancreatic islets, liver and visceral fat, shown in Western blots. …”

Longer exposure to MPA increases the CD4/CD8 ratio, decreases CD8+ T-cell frequency, and increases the density of the CCR5 coreceptor on CD4+ and CD8+ T-cells. by Michelle F. Maritz (5146730)

Fig 5 - by Kellie J. Walters (10451329)

Subjects:

Mean <i>μ</i>_<i>i</i> and standard deviation <i>σ</i>_<i>i</i> of <i>i</i> = [0%, 1%, 2.5%, 5%] concentration datasets. by Ishriak Ahmed (14265562)

Structure of P-YOLOv5s-GRNF. by Zhongjian Xie (4633099)

CII, inhibitor of SphK, decreases both the migration of HPAECs in a scratch assay <i>in vitro</i> and the content of S1P in HPAECs. by Evgeny V. Berdyshev (307465)

Increased AQP2 expression by a vasopressin analogue is decreased by NOX4 depletion in mpkCCD_cl4 cells. by Eric Féraille (513934)

Study flow chart. by Ruth Barclay (8428956)

“…Multivariate logistic regression models were developed for community ambulation. Mean age was 68 (SE 0.5) years (45% female). In the final community ambulation model (n = 855), factors associated with being less likely to ‘walk outdoors sometimes or often’ included difficulty or being unable to walk 2–3 blocks (decreased endurance) vs. no difficulty. …”

Participant characteristics (non-weighted). by Ruth Barclay (8428956)

“…Multivariate logistic regression models were developed for community ambulation. Mean age was 68 (SE 0.5) years (45% female). In the final community ambulation model (n = 855), factors associated with being less likely to ‘walk outdoors sometimes or often’ included difficulty or being unable to walk 2–3 blocks (decreased endurance) vs. no difficulty. …”

Community ambulation—Final model. by Ruth Barclay (8428956)

“…Multivariate logistic regression models were developed for community ambulation. Mean age was 68 (SE 0.5) years (45% female). In the final community ambulation model (n = 855), factors associated with being less likely to ‘walk outdoors sometimes or often’ included difficulty or being unable to walk 2–3 blocks (decreased endurance) vs. no difficulty. …”

Community ambulation—Initial model. by Ruth Barclay (8428956)

“…Multivariate logistic regression models were developed for community ambulation. Mean age was 68 (SE 0.5) years (45% female). In the final community ambulation model (n = 855), factors associated with being less likely to ‘walk outdoors sometimes or often’ included difficulty or being unable to walk 2–3 blocks (decreased endurance) vs. no difficulty. …”

Time course of best-corrected visual acuity (BCVA) in all eyes. by Yasuyuki Sotani (20114144)

Fig 5 - by Makenna B. McGill (15217451)

Annual treatment frequencies in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…Mean outpatient visits in the recurrence group decreased from 13.6 ± 3.0 to 11.9 ± 5.0, 8.1 ± 3.9, and 7.8 ± 3.2 at 1, 2, and 3 years postoperatively, respectively (Kruskal-Wallis test, p < 0.001). …”

Time course of central retinal thickness (CRT) in all eyes. by Yasuyuki Sotani (20114144)

“…<p>Mean CRT (μm ± standard deviation) significantly decreased from 504.7 ± 118.2 μm preoperatively to 302.5 ± 60.5 at 1 month, 307.5 ± 64.4 at 3 months, 286.8 ± 49.0 at 6 months, 305.3 ± 79.5 at 12 months, 288.8 ± 79.1 at 24 months, and 295.2 ± 87.4 at 36 months (Kruskal–Wallis test, P < 0.001; Dunn’s test, **P < 0.01). …”

Annual number of outpatient visits in all eyes. by Yasuyuki Sotani (20114144)

“…<p>Mean visit frequency (mean ± standard deviation) significantly decreased from 11.5 ± 4.3 preoperatively to 8.8 ± 4.1, 5.0 ± 3.4, and 4.4 ± 3.2 visits in the first, second, and third postoperative years, respectively (Kruskal–Wallis test, P < 0.001; Dunn’s test, **P < 0.01). …”

HAstV-1 infection leads to a time-dependent decrease in junctional protein levels. by Virginia Hargest (12447014)

Time course of central retinal thickness (CRT) in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…These values significantly decreased in the first postoperative year to 2.3 ± 2.6, 0.1 ± 0.3, 0.8 ± 1.6, 0, and 3.1 ± 2.8; in the second year to 2.1 ± 2.8, 0.4 ± 1.0, 0.0, 0.1 ± 0.3, and 2.6 ± 2.8; and in the third year to 2.0 ± 2.2, 0, 0.6 ± 1.7, 0.1 ± 0.3, and 2.8 ± 3.5 (Kruskal–Wallis test, p < 0.001; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0332941#pone.0332941.g007" target="_blank">Fig 7</a>). …”

Annual number of outpatient visits in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…<p>In the recurrence group, mean outpatient visits (± standard deviation) decreased from 13.6 ± 3.0 to 11.9 ± 5.0, 8.1 ± 3.9, and 7.8 ± 3.2 at 1, 2, and 3 years postoperatively, respectively (Kruskal-Wallis test, P < 0.001; Dunn’s test, **P < 0.01). …”