Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart by Akhtar, Saghir

“…Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …”
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Development of pH-Controlled Aluminum-Based Polymeric Gel for Conformance Control in Sour Gas Reservoirs by Shamlooh M.

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Anti-Metastatic and Anti-Tumor Growth Effects of Origanum majorana on Highly Metastatic Human Breast Cancer Cells: Inhibition of NFκB Signaling and Reduction of Nitric Oxide Produc... by Al Dhaheri, Yusra

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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills by Abbas, Tariq

“…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …”
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Heat stress impairs proprioception but not running mechanics by Mtibaa K.

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In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies. by Ismail, Hesham M

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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function by Da'as, Sahar I.

“…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation-contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l-type Ca2+ (Cav1.2), sodium (NaV1.5) and potassium (KV7.1) channels. …”
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Age-Related Differences of the Athlete`s Heart by Kneffel, Zsuzsanna

“…Results: In children age (<10-12 years) usually no or a small training effect can be detected. …”
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro by Rizk, Nasser Moustafa

“…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …”
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Improvement of heat sink performance using paraffin/graphite/hydrogel phase change composite coating by Sreedevi, Paramparambath

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Repositioning for pressure injury prevention in adults. by Gillespie, Brigid M

“…We searched the Cochrane Wounds Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Ovid MEDLINE, Ovid Embase, and EBSCO CINAHL Plus on 12 February 2019. …”
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM) by Mohammad, Hadi Ahmad

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Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region by Dagenais, Renée

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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. by Al-Jaber, Hend

“…To investigate insulin signaling's influence in vitro by IRinducing factors, we assessed phospho-protein levels. Our results reveal a significant p-Akt induction with chronic high insulin (10%) and acute TNFα (12%) treatment under hypoxia (both P<0.05). …”
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Burden of disease attributable to suboptimal diet, metabolic risks and low physical activity in Ethiopia and comparison with Eastern sub-Saharan African countries, 1990-2015: findi... by Melaku, Yohannes Adama

“…While the age-adjusted proportion of all-cause mortality attributable to CMU decreased significantly between 1990 and 2015, it increased from 10.8% [95% UI: 8.8-13.3] to 14.5% [95% UI: 11.7-18.0] for dietary risks and from 17.0% [95% UI: 15.4-18.7] to 24.2% [95% UI: 22.2-26.1] for metabolic risks. …”
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Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries by Pathadka, Swathi

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Impacts of rural tourism-driven land use change on ecosystems services provision in Erhai Lake Basin, China by Li, Jinghui

“…The results show that constructed area in ELB, especially in the lakeside zone, increased strongly from 2000 to 2015 due to a tourism boom (in which tourism revenues increased 12-fold), at the expense of farmland, grassland, and forest. …”
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Dynamic Imaging of Hydrate Specific Area Evolution during Xenon Hydrate Formation by Jarrar, Zaher

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Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate by Nazir, Roshan

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The Impact of Multiple Autoclave Cycles on the Surface Roughness of Thermally Treated Nickel-Titanium Endodontic Files by Ba-Hattab, Raidan

“…An unsterilized group was assigned as the pre-autoclaving group (Cycle 0), and the other three groups underwent various autoclave sterilization cycles (Cycles 1, 5, and 10). The roughness average (Ra), root mean square (Rq), and average maximum peak-to-valley height (Rz) values were evaluated using SEM and ImageJ software. …”
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