Rare coding variants pinpoint genes that control human hematological traits by Abdou Mousas (4336705)

“…We found 56 such rare coding or splice site variants at <i>P</i><5x10^-8, including 31 that are associated with a blood-cell phenotype for the first time. …”

Table1_Bifidobacterium longum CECT 7894 Improves the Efficacy of Infliximab for DSS-Induced Colitis via Regulating the Gut Microbiota and Bile Acid Metabolism.DOCX by Fangfei Xiao (11951737)

“…</p><p>Methods: C57BL/6 mice were treated with phosphate-buffered saline (PBS) or B. longum CECT 7894 (5 × 10⁸ CFU/day) once daily by gavage for 5 days and subsequently induced acute colitis by 3% (w/v) DSS in drinking water. …”

Data_Sheet_1_Dry Season Transpiration and Soil Water Dynamics in the Central Amazon.docx by Gustavo C. Spanner (6893450)

“…To scale tree water use to the plot level (stand transpiration), basal area was measured for all trees within a 5 m radius around each soil moisture probe. The sensitivity of tree transpiration to reduced precipitation varied by tree, with some increasing and some decreasing in water use during the dry period. …”

Suppression of TSC2 expression in response to Notch activation in EBs. by Subir Kapuria (121321)

“…<p>A, B. Over-expression of N intracellular domain (N^ICD; using esg::Gal4, tub:Gal80^ts combined with the N reporter Su(H)-Gbe::lacZ) decreases TSC2 levels in stem cells (arrowheads). …”

DataSheet_1_17β-Estradiol Induces Mitophagy Upregulation to Protect Chondrocytes via the SIRT1-Mediated AMPK/mTOR Signaling Pathway.pdf by Runhong Mei (10089769)

“…The chondrocytes viability and proliferation were determined by MTT and 5-Bromo-2’-deoxyuridine (BrdU) assay. These experiments were independently repeated 3 times The study found that 17β-E2 increased the expression level of SIRT1, p-AMPK, and mitophagy-related proteins but decreased p-mTOR expression, and then induced mitophagy upregulation in chondrocytes. …”

Trends and predictors of mother-to-child transmission of HIV in an era of protocol changes: Findings from two large health facilities in North East Nigeria by Ademola Joshua Itiola (7846871)

“…<div><p>Background</p><p>Research studies have demonstrated a reduction in the risk of mother-to-child transmission of HIV (MTCT) to less than 2%, or 5% in non-breastfeeding and breastfeeding populations, respectively, with antiretroviral interventions. …”

Image2_Bifidobacterium longum CECT 7894 Improves the Efficacy of Infliximab for DSS-Induced Colitis via Regulating the Gut Microbiota and Bile Acid Metabolism.TIF by Fangfei Xiao (11951737)

“…</p><p>Methods: C57BL/6 mice were treated with phosphate-buffered saline (PBS) or B. longum CECT 7894 (5 × 10⁸ CFU/day) once daily by gavage for 5 days and subsequently induced acute colitis by 3% (w/v) DSS in drinking water. …”

DataSheet_2_Body composition and inflammation variables as the potential prognostic factors in epithelial ovarian cancer treated with Olaparib.pdf by Xingzi Guo (18440394)

“…</p>Results<p>The median follow-up duration was 16 months (range: 5-49 months). Survival analysis indicated that high SATI, high VATI, high SMI, high BMD, low NLR, and low PLR were associated with decreased risk of disease progression (all p < 0.05). …”

Negative regulation of Tkv protein level by S6KL via proteasomal degradation pathway. by Guoli Zhao (699622)

“…Actin was used as a loading control. (D) Tkv protein level was increased in S2 cells expressing a reduced level of S6KL. …”

Socio-behavioral risk factors among older adults living with HIV in Thailand by Patou Masika Musumari (509494)

“…<div><p>Background</p><p>There has been a global increase in HIV infection in persons 50 years of age and older. …”

Table_1_Work-related injuries of rehabilitation therapists and measures for prevention.DOCX by Wei Liu (20030)

“…Specifically, neuro-physiotherapists (OR [95% CI]: 3.04 [1.56–5.92]), musculoskeletal physiotherapists (OR [95% CI]: 2.46 [1.16–5.18]), and intensive care physiotherapists (OR [95% CI]: 4.70 [1.24–17.88]) were at higher risk. …”

Image 1_Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation.tif by Jingyi Hou (698975)

“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.…”

Protective Effects of Triphala on Dermal Fibroblasts and Human Keratinocytes by Sandeep R. Varma (843403)

“…TE increased collagen-I, involucrin and filaggrin synthesis by 70.72 ± 2.3%, 67.61 ± 2.1% and 51.91 ± 3.5% in HDF or HaCaT cells respectively. TE also exhibited anti-tyrosinase and melanin inhibition properties in a dose-dependent manner. …”

Image1_Jia-Wei-Yu-Ping-Feng-San Attenuates Group 2 Innate Lymphoid Cell-Mediated Airway Inflammation in Allergic Asthma.JPEG by Lingna Xue (11101695)

“…Jia-Wei-Yu-Ping-Feng-San (JWYPFS), a traditional Chinese medicine, has been widely used to treat asthma in China. …”

RNA-Seq Transcriptomic Responses of Full-Thickness Dermal Excision Wounds to <i>Pseudomonas aeruginosa</i> Acute and Biofilm Infection by S. L. Rajasekhar Karna (320813)

“…Additionally, the raw counts of multiple types of differentially-expressed ncRNAs increased on post-wounding day 3 in control wounds, but infection suppressed this increase. After 5 and 9 days, these ncRNA counts in control wounds decreased, whereas they increased in the infected, healing-impaired wounds. …”

DataSheet_1_Body composition and inflammation variables as the potential prognostic factors in epithelial ovarian cancer treated with Olaparib.pdf by Xingzi Guo (18440394)

“…</p>Results<p>The median follow-up duration was 16 months (range: 5-49 months). Survival analysis indicated that high SATI, high VATI, high SMI, high BMD, low NLR, and low PLR were associated with decreased risk of disease progression (all p < 0.05). …”

Image1_Bifidobacterium longum CECT 7894 Improves the Efficacy of Infliximab for DSS-Induced Colitis via Regulating the Gut Microbiota and Bile Acid Metabolism.TIF by Fangfei Xiao (11951737)

“…</p><p>Methods: C57BL/6 mice were treated with phosphate-buffered saline (PBS) or B. longum CECT 7894 (5 × 10⁸ CFU/day) once daily by gavage for 5 days and subsequently induced acute colitis by 3% (w/v) DSS in drinking water. …”

Hyperhidrosis Prevalence and Demographical Characteristics in Dermatology Outpatients in Shanghai and Vancouver by Yudan Liu (2623240)

“…Primary HH has highest prevalence in those younger than 30 years of age, decreasing dramatically in later years. Caucasian subjects are at least 2.5 times more likely to develop axillary hyperhidrosis compared to Chinese subjects. …”

Functional <i>IL6R</i> 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases by Ricardo C. Ferreira (174523)

“…We demonstrate that, although 358Ala increases transcription of the soluble <i>IL6R</i> isoform (<i>P</i> = 8.3×10⁻²²) and not the membrane-bound isoform, 358Ala reduces surface expression of IL-6R on CD4+ T cells and monocytes (up to 28% reduction per allele; <i>P</i>≤5.6×10⁻²²). Importantly, reduced expression of membrane-bound IL-6R resulted in impaired IL-6 responsiveness, as measured by decreased phosphorylation of the transcription factors STAT3 and STAT1 following stimulation with IL-6 (<i>P</i>≤5.2×10⁻⁷). …”

Table 1_Protocatechuic aldehyde ameliorates high glucose-induced podocyte injury by attenuating inflammation, oxidative stress, and apoptosis via suppression of endoplasmic reticul... by Yishu Wang (845334)

“…</p>Objective<p>To investigate the effects and mechanism of PCA on high glucose-induced podocyte inflammation, oxidative stress, and apoptotic injury.</p>Methods<p>A podocyte injury model was established by treating mouse podocytes (MPC5) with high-glucose medium. …”