Preclinical Evaluation of Engineered Oncolytic Herpes Simplex Virus for the Treatment of Pediatric Solid Tumors by Michael L. Megison (469463)

“…<div><p>Recently, investigators showed that mice with syngeneic murine gliomas that were treated with a neuroattenuated oncolytic herpes simplex virus-1 (oHSV), M002, had a significant increase in survival. …”

Experimental Evidence for the Effect of Small Wind Turbine Proximity and Operation on Bird and Bat Activity by Jeroen Minderman (146256)

“…At shorter distances from operating turbines (0–5 m), bat activity (measured as the probability of a bat “pass” per hour) decreases from 84% (71–91%) to 28% (11–54%) as wind speed increases from 0 to 14 m/s. …”

Table_1_The Choice of Candidates in Survival Markers Based on Coordinated Gene Expression in Renal Cancer.xlsx by Natalya Apanovich (10780218)

“…Specifically, the high correlation coefficient of EGLN3 and NDUFA4L2 expression may indicate the importance of the coordinated regulation of glycolysis and mitochondrial metabolism. A panel of CA9, EGLN3, BHLHE41, and VWF enabled the prediction of survival for more than 3.5 years in patients with ccRCC, with a probability close to 90%. …”

DataSheet1_Preclinical Evaluation of Fingolimod in Rodent Models of Stroke With Age or Atherosclerosis as Comorbidities.docx by Andrea C. Diaz Diaz (13037151)

“…Tissue damage was evaluated at 7 days. A lower dose of fingolimod, 0.5 mg/kg, but not 1 mg/kg, increased lesion size but decreased ipsilateral brain atrophy in younger mice, without an effect on behavioural outcomes. …”

Stability and Structure of Hydrated Amorphous Calcium Carbonate by Yuriy G. Bushuev (1492837)

Inhibition of TGF-β signaling in EC-10T1/2 cell coculture leads to increased EC apoptosis. by Tony E. Walshe (269700)

“…<p>(A–B) Transwell cocultures of BAECs and 10T1/2 cells in the presence and absence of SB-431542, an inhibitor of ALK5. …”

Supplementary Material for: The Conundrum of Papillary Breast Lesions within the C3 Category by Weigner J. (4146718)

“…Features specific to papillary lesions within C3 include macropapillary fragments, complex sheets, palisading strips, cystic background, cohesion and a decreased nuclear-to-cytoplasmic ratio. Features favouring atypical/malignant papillary lesions include decreased numbers of bare bipolar nuclei, discohesion and a non-cystic background. …”

Figure 4 The Gαo RGS EGL-10 is required in rectal epithelial cells to regulate the immune response and affect pathogen clearance by Rachel Mcmullan (506214)

“…<p>egl-10 mutants were infected with M. nematophilum using either standard assay conditions (small lawn) or conditions where animals were unable to avoid the pathogen (big lawn) and the percentage of Dar progeny scored. egl-10(n692) and egl-10(md176) significantly decreased the percentage of Dar animals (A). Expression of EGL-10 cDNA, using a heatshock-inducible promoter, at L1, L2/L3 and L3/L4 stage (hs∷EGL-10), or a rectal epithelial promoter (egl-5p∷EGL-10), rescued the Dar phenotype in egl-10(n692) animals (A). …”

C4BP in gonococcal pathogenesis. by Lacie M. Werner (14710419)

“…<i>gonorrhoeae</i> with neutrophils, but not bacteria that are opsonized with IgG or that express Opa proteins that engage other ligands (5). As a consequence, C4BP enhances survival of <i>N</i>. …”

Ubqn binds to APP via its UBA domain and modulates APP levels. by Garrett G. Gross (49833)

“…<p>(A–F) SEMs of adult fly eyes of various genotypes. …”

DataSheet1_Tunable Thermo-Responsive Properties of Hydroxybutyl Chitosan Oligosaccharide.docx by Chong Chen (360710)

“…The LCST of HBCOS with a DS of 4.66 decreased to 33.5°C and 30°C as the HBCOS and NaCl concentrations increased to 50 mg/ml and 4% (w/v), respectively. …”

DataSheet1_Monitoring the impact of the COVID-19 lockdown on air quality in Lanzhou: Implications for future control strategies.docx by Hui Liu (33624)

“…NO₂, PM_2.5 and O₃ maintained the trend of the previous five years. …”

The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity by Erin K. Butler (185540)

“…Moreover, TRAP1 was able to prevent alteration in mitochondrial morphology caused by [A53T]α-Synuclein overexpression in human SH-SY5Y cells. …”

Serum uPA and suPAR levels of osteosarcoma-bearing and clinically healthy dogs. by Arata Matsuyama (7874123)

“…(A) Dogs with osteosarcoma had higher presurgical serum uPA level (n = 26) than clinically healthy dogs (n = 6; p = 0.008) and the level decreased postoperatively (n = 25; P < 0.001). …”

Proliferative capacity of long-term vaccine-elicited human T cells. by Nathifa Moyo (2838644)

“…<p>Cryopreserved and thawed PBMCs from pre-vaccination (Pre), 6 months (6m), and 1 (1y) and 2 (2y) years after the last vaccine administration were labelled with CFSE, stimulated with pools of stimulatory 15-mer peptides assembled for each returning volunteer for 5 days and analyzed using flow cytometry for dividing (decreased CFSE) CD4⁺ and CD8⁺ T cells. …”

hCRM1 expression in mouse cells improves Gag assembly efficiency and trafficking to the plasma membrane. by Nathan M. Sherer (86591)

“…(D) 3T3 cells were transfected with 0.25 µg Rev and 0.5 µg hCRM1 or luciferase plasmids plus decreasing amounts of GP-RRE plasmid as indicated. …”

Differential hepatic gene expression in NAFLD progression. by Michael Kriss (9188674)

“…<p>Heat map representing color-coded expression levels of differentially expressed genes (FDR<0.01, p<0.01) for each individual sample across the three cohorts (normal, NAS ≤3, and NAS ≥5). A total of 211 genes are included in the heatmap. …”

Binding experiment of hE3 to hCD137L by ELISA assay. by Ling Yi (184648)

“…<p>hE3, which is hIgG1-Fc fusion protein expressed by pCDH, containing hCD137 CRD I+II. hCD137L-mFc was coated at 1 µg/ml and a series of decreasing concentration of hE3, 10 µg/ml, 5 µg/ml, 1 µg/ml and 0.2 µg/ml were added, followed by detecting with HRP-goat-anti-human IgG. …”

Raw data of Metagenomic analysis of Tongxie Yaofang in treating rat model of ulcerative colitis with the "liver depression and spleen deficiency" syndrome by Yan Wang (11942856)

Transdifferentiation and <i>CYB561</i> knockdown altered the Fe²⁺ concentrations and expression of iron responsive genes (IRGs) in LNCaP cells. by Romie Angelo G. Azur (18547651)