Transfusion: -80°C Frozen Blood Products Are Safe and Effective in Military Casualty Care by Femke Noorman (3396926)

“…In hospital mortality decreased post-MTP for MT patients from 44% to 14% (P = 0.005) and for non-MT patients from 12.7% to 5.9% (P = 0.139). …”

DataSheet_1_GhWRKY70D13 Regulates Resistance to Verticillium dahliae in Cotton Through the Ethylene and Jasmonic Acid Signaling Pathways.pdf by Xian-Peng Xiong (8615040)

“…However, little has been reported on the functions of WRKYs in cotton's resistance to V. dahliae. Here, we identified 5, 5, and 10 WRKY70 genes in Gossypium arboreum, Gossypium raimondii, and Gossypium hirsutum, respectively, and investigated the expression profiles of all GhWRKY70 genes in various cotton tissues and in response to hormone treatment or V. dahliae infection. …”

Data_Sheet_2_Single-cell transcriptome revealed dysregulated RNA-binding protein expression patterns and functions in human ankylosing spondylitis.docx by Zheng Ren (1766506)

“…</p>Methods<p>PBMC sample data from scRNA-seq (HC*29, AS*10) and bulk RNA-seq (NC*3, AS*5) were selected for correlation analysis.</p>Results<p>(1) Compared with the HC group, the numbers of B, DC (dendritic cells), CD14⁺ Mono and CD8⁺ T cells were increased in AS group, while the numbers of platelet (platelets), CD8⁺ NKT, CD16⁺ Mono (non-classical monocytes), Native CD4⁺ T and NK were decreased. (2) Through the analysis of RBP genes in B cells, some RBPs were found to play an important role in B cell differentiation and function, such as DDX3X, SFPQ, SRRM1, UPF2. (3) It may be related to B-cell receptor, IgA immunity, NOD-like receptor and other signaling pathways; Through the analysis of RBP genes in CD8⁺ T cells, some RBPs that play an important role in the immune regulation of CD8⁺ T were found, such as EIF2S3, EIF4B, HSPA5, MSL3, PABPC1 and SRSF7; It may be related to T cell receptor, TNF, IL17 and other signaling pathways. (4) Based on bulk RNA-seq, it was found that compared with HC and AS patients, differentially expressed variable splicing genes (RASGs) may play an important role in the occurrence and development of AS by participating in transcriptional regulation, protein phosphorylation and ubiquitination, DNA replication, angiogenesis, intracellular signal transduction and other related pathways.…”

Table_10_Preliminary prediction of semen quality based on modifiable lifestyle factors by using the XGBoost algorithm.docx by Mingjuan Zhou (12880019)

“…Introduction<p>Semen quality has decreased gradually in recent years, and lifestyle changes are among the primary causes for this issue. …”

DataSheet8_Guanxinkang Decoction Attenuates the Inflammation in Atherosclerosis by Regulating Efferocytosis and MAPKs Signaling Pathway in LDLR−/− Mice and RAW264.7 Cells.docx by Yifan Zhang (119570)

“…<p>Guanxinkang decoction (GXK), a traditional Chinese medicinal drug, is used to treat cardiovascular disease. …”

Image_1_Effect of Body Mass Index on the Prognosis of Liver Cirrhosis.JPEG by Yue Yin (320688)

“…BMI was calculated and categorized as underweight (BMI <18.5 kg/m²), normal weight (18.5 ≤ BMI < 23.0 kg/m²), and overweight/obese (BMI ≥ 23.0 kg/m²).…”

Table_3_Preliminary prediction of semen quality based on modifiable lifestyle factors by using the XGBoost algorithm.docx by Mingjuan Zhou (12880019)

“…Introduction<p>Semen quality has decreased gradually in recent years, and lifestyle changes are among the primary causes for this issue. …”

Oxidative stress assessed by 4-HNE staining. by Kanako Tamura (734618)

“…Data are means ± SEM of 4–5 mice in each group. *<i>p</i> < 0.05, **<i>p</i> < 0.01</p>…”

Novel long non-coding RNA lnc-URIDS delays diabetic wound healing by targeting Plod1 by Ada Admin (8524211)

“…</a><a>The binding of lnc-URIDS to Plod1 results in a decreased protein stability of Plod1, which ultimately leads to the dysregulation of collagen production and deposition and delays wound healing. …”

Ultrasensitive dependence of the overall elongation rate on EF-Tu concentration in <i>E. coli</i>. by Sophia Rudorf (169011)

“…<p>A) Theoretical predictions for <i>E. coli</i> growing at a specific growth rate of 2.5 h⁻¹ with a physiological EF-Tu concentration of about 250 μM (blue dashed line) [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006979#pcbi.1006979.ref032" target="_blank">32</a>]. …”

Cutaneous leishmaniasis in Costa Rica: Deforestation and El Niño Southern Oscillation (ENSO). by Luis Fernando Chaves (19596)

“…The difference is statistically significant as shown by a one tail Welch's t-test (a test robust to differences in variance) in which the alternative hypothesis is that the difference in forest cover between 1 and 2 is larger than 0 (<i>Welch's t</i> =  2.14, d.f. = 5.9, p<0.038).…”

Table 1_Impact of catheter-to-vein diameter ratio on thrombosis in pediatric central venous catheterization.pdf by Fevzi Kahveci (15121585)

“…</p>Conclusion<p>In conclusion, selecting a catheter with a diameter-to-vessel diameter ratio of less than 1:5 in normovolaemic paediatric patients should be considered as a strategy to reduce the risk of catheter-related thrombosis.…”

Modular organization of the Class I phenotypically plastic transcriptome. by Shanshan Zhou (175668)

“…The <i>Cyp</i> transcripts are distributed across multiple modules, which may reflect their specialized functions. However, <i>Cyp6a21</i>, <i>Cyp6a2</i>, and <i>Cyp6d5</i>, along with <i>Ugt86Dd</i>, group in module 18; <i>Cyp6w1</i> and <i>Cyp6a8</i>, co-vary in module 49; <i>Cyp6a17</i>, <i>Cyp12a4</i>, and <i>Cyp9f2</i> cluster in module 68; and, <i>Cyp4d1</i> and <i>Cyp4ad1</i>, both associated with aging, co-vary in module 101. …”

Time evolution of two competing clones of T cells with different antigenic-specificities. by Anmar Khadra (221668)

“…The subclone in panel (A2) has the same parameter values as the “standard clone” used in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0014796#pone-0014796-g005" target="_blank">Fig. 5</a> (white circle). …”

Metabolic Characterization of Dairy Cows Treated with Gossypol by Blood Biochemistry and Body Fluid Untargeted Metabolome Analyses by Chaohua Tang (4517047)

“…Milk quality was adversely affected, as both milk protein and lactose levels were significantly decreased in the gossypol-treated group (3.40% vs 3.16%, <i>P</i> = 0.044; 5.15% vs 4.91%, <i>P</i> = 0.027; respectively). …”

Metabolic Characterization of Dairy Cows Treated with Gossypol by Blood Biochemistry and Body Fluid Untargeted Metabolome Analyses by Chaohua Tang (4517047)

“…Milk quality was adversely affected, as both milk protein and lactose levels were significantly decreased in the gossypol-treated group (3.40% vs 3.16%, <i>P</i> = 0.044; 5.15% vs 4.91%, <i>P</i> = 0.027; respectively). …”

Inactivation of <i>Mbnl1</i> does not alter anxiety in the Elevate Plus Maze. by Anna Matynia (46702)

“…D) <i>Mbnl1^−/−</i> (white, n = 14) mutant mice display decreased numbers of head dips (F(1,26) = 5.1, p = 0.032) compared to their <i>Mbnl1^+/+</i> wild type littermate controls (black, n = 14), incidcative of increased anxiety, in contrast to B).…”

Theta phase modulates higher frequency amplitudes during inhale, when odor is present. by Qiaohan Yang (8892716)

“…The overall magnitude of beta oscillations increased and decreased rhythmically with a frequency in the theta range, particularly in the first 1.5 to 2 s of the response (gray box). …”

Data_Sheet_1_Transient Early Fine Motor Abnormalities in Infants Born to COVID-19 Mothers Are Associated With Placental Hypoxia and Ischemia.docx by Huan-Yu Liu (3491906)

“…The placental tissues were examined for SARS-CoV-2 infection, pathological changes, cytokines, and mtDNA content.…”

Overview of the impact of the stress axis (hypothalamus-pituitary-adrenal axis) on the reproductive axis (hypothalamus-pituitary-gonadal axis). by Derek Alsop (371419)

“…Cortisol (purple arrows) modulates reproductive process in the hypothalamus, pituitary and testis <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0006463#pone.0006463-Sapolsky1" target="_blank">[5]</a>. …”