Pyrvinium inhibits WNT signaling in CRC cells. by Bin Li (39349)

“…Immunoblots show that Pyrvinium decreases PYGOPUS2 levels in both SW480 and HCT116 WTKO cells in a dose-dependent manner. …”

Methyl Gallate from <i>Galla rhois</i> Successfully Controls Clinical Isolates of <i>Salmonella</i> Infection in Both <i>In Vitro</i> and <i>In Vivo</i> Systems by Jang-Gi Choi (5659999)

“…Oral administration of MG showed a strong anti-bacterial activity against WS-5 infected BALB/c mice. …”

Neto prodomain affects synapse structure and function. by Young-Jun Kim (696507)

“…Details are shown in lower panels and a larger field in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004988#pgen.1004988.s005" target="_blank">S5 Fig.…”

Table_3_Mortality Rate of Lymphoma in China, 2013–2020.docx by Weiping Liu (47182)

“…<p>Lymphoma is a malignant disease that threatens human health and imposes a significant burden on the society burden; however, there are limited accurate mortality data on lymphoma in China. …”

DataSheet1_Lifestyle Behaviours of Children and Adolescents During the First Two Waves of the COVID-19 Pandemic in Switzerland and Their Relation to Well-Being: An Observational St... by Gabriela P. Peralta (8982482)

“…</p><p>Results: The percentage of children meeting the recommendations for PA and ST decreased from the pre-pandemic period to the first wave, with a slight recovery during the second wave. …”

Image_1_Case Report: Low-Dose Apatinib in the Treatment of Intrahepatic Biliary Cystadenoma With Recurrence and Malignant Transformation.tif by Yongguang Yang (3144873)

“…Regular re-examination showed that the tumor had significantly decreased in size. On January 16, 2021, a CT scan revealed a tumor diameter of 4.5 cm. …”

Table1_Rethinking the prognosis model of differentiated thyroid carcinoma.docx by Liang He (305820)

“…The new system had a higher proportion of variance explained (PVE) (5.04%) and lower Akaike information criterion (AIC) (18,331.906) than the 8th TNM staging system (a PVE of 4.11% and AIC of 18,692.282). …”

Aberrant Promoter Methylation and Expression of UTF1 during Cervical Carcinogenesis by Samuel Guenin (146387)

“…Surprisingly, direct bisulfite pyrosequencing revealed that the inhibition of DNA methyltransferase by 5-aza-2′-deoxycytidine was associated with decreased <em>UTF1</em> gene methylation and expression in two cervical cancer cell lines of the four tested. …”

Mortality analysis of adult burn patients in Uruguay by Martín Angulo (10437629)

“…A need for mechanical ventilation (OR 8.80; 95%CI 5.68 - 13.62), older age (OR 1.07 per year; 95%CI 1.06 - 1.09), total body surface area burned (OR 1.05 per 1%; 95%CI 1.03 - 1.08) and extension of third-degree burns (OR 1.05 per 1%; 95%CI 1.03 - 1.07) were independent risk factors for mortality. …”

Carbonic Anhydrase Generates CO₂ and H⁺ That Drive Spider Silk Formation Via Opposite Effects on the Terminal Domains by Marlene Andersson (610369)

“…Surprisingly, the terminal domains respond in opposite ways when pH is decreased from 7 to 5: Urea denaturation and temperature stability assays show that NT dimers get significantly stabilized and then lock the spidroins into multimers, whereas CT on the other hand is destabilized and unfolds into ThT-positive β-sheet amyloid fibrils, which can trigger fiber formation. …”

Ameliorative impact of Juniperus Macrocarpa extract on methotrexate-induced hepatic damage in rats by Shahad Hassan Hadi (20141025)

“…Rats in groups 3 and 4 were given daily dosages of 100 mg and 200 mg of Juniperus macrocarpa aqueous extract, respectively, for two weeks before receiving a single intraperitoneal MTX injection. Juniperus macrocarpa extracts at both low and high doses substantially alleviated the MTX-provoked biochemical alterations, as evidenced by decreased levels of inflammatory parameters including TNF-α and IL-6 and hepatic enzymes including ALT, AST, and ALP. …”

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease by Kyota Fujita (258978)

“…The concentration-dependency of H₂ showed that H₂ as low as 0.08 ppm had almost the same effect as saturated H₂ water (1.5 ppm). MPTP-induced accumulation of cellular 8-oxoguanine (8-oxoG), a marker of DNA damage, and 4-hydroxynonenal (4-HNE), a marker of lipid peroxidation were significantly decreased in the nigro-striatal dopaminergic pathway in mice drinking H₂-containing water, whereas production of superoxide (O₂•⁻) detected by intravascular injection of dihydroethidium (DHE) was not reduced significantly. …”

Table_1_Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.XLSX by Hantao Wang (760364)

“…Finally, miRNAs targeting BTF3 were predicted and validated. Decreased miR-497-5p expression is responsible for higher levels of BTF3 post-transcriptionally. …”

Feeding effects of cottonseed and its co-products on the meat proteome from ram lambs by Tiago do Prado Paim (5671568)

“…The effect of gossypol (a compound present in cotton co-products) in ruminant metabolism and meat quality is not yet clear. …”

Effect of <i>Trypanosoma cruzi</i> AP-1 γ subunit (TcAP1-γ) gene knockout on cruzipain expression and localization. by Claudia Maria do Nascimento Moreira (4287679)

“…In γKO epimastigotes, the levels of the zymogen form (57 kDa) of TcCZP were increased, while the levels of the mature enzyme (51 kDa) were decreased (to a faint band) compared with the WT. Labeling for the <i>T</i>. …”

Different expressions of immune components in ascites of early- and advanced-stage ovarian cancer patients. by Yu-Li Chen (126600)

“…C1, IL-4; C2, TNF-α; C3, TGF-β; C4, IL-6; C5, IL-10; C6, IFN-γ. <i>Note</i>: The IL-4 and TNF-α concentrations decreased while the TGF-β, IL-6, IL-10, and IFN-γ concentrations increased from early to advanced stage.…”

Table_3_Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.XLSX by Hantao Wang (760364)

“…Finally, miRNAs targeting BTF3 were predicted and validated. Decreased miR-497-5p expression is responsible for higher levels of BTF3 post-transcriptionally. …”

Computer simulations confirm involvement of <i>I_m</i> and <i>I_h</i> in resonance and allow the dissection of their respective contributions at different volta... by Jorge Vera (432199)

“…<i>C, D</i>, Same as in A, B, but at −65 mV; <i>I_m</i> removal clearly reduced resonance (Q = 1.12, compared to 1.35 for control; <i>f_res</i> decreased from 3.7 to 2.0 Hz). …”

Image_1.pdf by Sipla Aggarwal (4912828)

“…Four non-segregating RNAi lines of wheat were selected for detailed study (S3-D-6-1; S6-K-3-3; S6-K-6-10 and S16-D-9-5). Homozygous transgenic RNAi lines at T₄ seeds with a decreased transcript of TaIPK1 showed 28–56% reduction of the PA. …”

Supplementary Material for: Trends in incidence of intracerebral hemorrhage and its bleeding sites from 1985 to 2017 in Japanese rural communities by figshare admin karger (2628495)

“…The proportions of bleeding sites were 37%, 29%, and 31% for putamen in 1985-1995, 1996-2006, and 2007-2017, respectively; the corresponding proportions were 24%, 35%, and 18% for thalamus; 10%, 10%, and 21% for lobes; 2%, 8%, and 12% for cerebellum; and 8%, 6%, and 5% for brain stem. Conclusion: The age-adjusted incidence declined by 33% from the 1990s with a large reduction in the early 1990s in Japanese rural communities. …”