Model for the adaptive pathogenicity of <i>S</i>. Typhimurium to the host environment via the sequential modulation of RNase III and RNase G endoribonucleolytic activity. by Minho Lee (50566)

“…H-NS usually represses <i>hilA</i> gene expression; however, decreased cellular H-NS levels appear to activate the <i>hilA</i> promoter. …”

BEEM-Static robustly filters samples violating modeling assumption in simulated and real datasets. by Chenhao Li (822769)

Nickel (ii) effects on Anammox reaction: reactor performance, dehydrogenase, sludge morphology and microbial community changes by Jian Cheng (48763)

“…The results showed that when the concentration of Ni²⁺ was 0.5 mg/L, the bioreactor had the highest denitrification efficiency, while the removal efficiency of ammonia nitrogen and nitrite nitrogen gradually decreased at concentrations higher than 2 mg/L, and the removal rates of ammonia nitrogen and nitrite nitrogen were 26% and 39.81% at the end of the experiment, respectively. …”

Exposure to Perfluorooctane Sulfonate In Utero Reduces Testosterone Production in Rat Fetal Leydig Cells by Binghai Zhao (509145)

“…<div><p>Background</p><p>Perfluorooctane sulfonate (PFOS) is a synthetic material that has been widely used in industrial applications for decades. …”

Differential gene GO enrichment analysis. by Jing Li (10611)

“…The results obtained were as follows: (1) Short-term low concentration of Cd stress (20 mg/kg) had a transient promotion effect on the growth of sisal roots, but Cd showed a significant inhibitory effect on the growth of sisal roots over time. (2) Under different concentrations of Cd stress, the Cd content in sisal root was greater than that in sisal leaf, and Cd accumulated mainly in sisal roots. (3) With the increase of Cd stress concentration, the antioxidant enzyme catalase activity increased, peroxidase activity showed a decreasing trend, and superoxide dismutase showed a trend of increasing and then decreasing. (4) Transcriptome sequencing analysis detected 123 differentially expressed genes (DEGs), among which 85 genes were up-regulated and 38 genes were down-regulated. …”

RNA sequencing results. by Jing Li (10611)

“…The results obtained were as follows: (1) Short-term low concentration of Cd stress (20 mg/kg) had a transient promotion effect on the growth of sisal roots, but Cd showed a significant inhibitory effect on the growth of sisal roots over time. (2) Under different concentrations of Cd stress, the Cd content in sisal root was greater than that in sisal leaf, and Cd accumulated mainly in sisal roots. (3) With the increase of Cd stress concentration, the antioxidant enzyme catalase activity increased, peroxidase activity showed a decreasing trend, and superoxide dismutase showed a trend of increasing and then decreasing. (4) Transcriptome sequencing analysis detected 123 differentially expressed genes (DEGs), among which 85 genes were up-regulated and 38 genes were down-regulated. …”

Table 6_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Long-Term Trends of Per- and Polyfluoroalkyl Substances (PFAS) in Suspended Particular Matter from German Rivers Using the Direct Total Oxidizable Precursor (dTOP) Assay by Bernd Göckener (7527578)

“…Trends based on target analysis (∑PFCA_target: −10.0%, ∑PFSA_target: −8.2%) were more pronounced than in the dTOP analysis (∑PFCA_dTOP: −4.2%; ∑PFSA_dTOP: −5.3%), suggesting that conventional target analysis overestimated actual decreases as precursors are not considered. …”

Data_Sheet_1_Inhibition of phosphorus removal performance in activated sludge by Fe(III) exposure: transitions in dominant metabolic pathways.docx by Yiyihui Hong (18812251)

“…</p>Results<p>Experimental results revealed that prolonged Fe(III) exposure induced a transition in the dominant phosphorus removal mechanism within activated sludge, resulting in a diminished availability of phosphorus for bio-metabolism. …”

DataSheet1_Glacier Runoff Variation Since 1981 in the Upper Naryn River Catchments, Central Tien Shan.zip by Tomas Saks (10861360)

“…The basins contain more than 1,000 glaciers, which cover a total area of 776 km². We model the mass balance and runoff contribution of all glaciers with a simplified energy balance melt model and distributed accumulation model driven by ERA5 LAND re-analysis data for the time period of 1981–2019. …”

Table 1_Dose-dependent effects of testosterone on proteins related to nitric oxide signaling pathway and trophic factors in the spinal cord of adolescent trained rats.docx by Katarzyna Nierwińska (6321125)

“…</p>Methods<p>Adult male Wistar rats were trained using a motor-driven treadmill for 6 weeks (40–60 min, 5 times per week) and/or were treated for 6 weeks with two doses of testosterone (i.m.; 8 mg/kg or 80 mg/kg body weight). …”

Supplementary Material for: Plasma Xanthine Oxidase Activity Is Predictive of Cardiovascular Disease in Patients with Chronic Kidney Disease, Independently of Uric Acid Levels by Gondouin B. (4157221)

“…Oxidative stress seems to play a pivotal role in this process, and purine metabolism may be involved in CKD-related oxidative stress. …”

DataSheet1_Glacier Runoff Variation Since 1981 in the Upper Naryn River Catchments, Central Tien Shan.zip by Tomas Saks (10861360)

“…The basins contain more than 1,000 glaciers, which cover a total area of 776 km². We model the mass balance and runoff contribution of all glaciers with a simplified energy balance melt model and distributed accumulation model driven by ERA5 LAND re-analysis data for the time period of 1981–2019. …”

Data Sheet 1_Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses.docx by Chengyu Yang (10223976)

“…Background<p>Chemotherapy is a prevalent and extensively utilized cancer treatment modality. …”

Table 3_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Table_1_Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1.DOCX by Shuai Mao (1627021)

“…<p>Left ventricular (LV) adverse remodeling and the concomitant functional deterioration contributes to the poor prognosis of patients with myocardial infarction (MI). Thus, a more effective treatment strategy is needed. …”

Table 1_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati... by Yueming Zhang (790755)

“…</p>Conclusion<p>HQH mitigates CYP-induced hippocampal neurotoxicity by decreasing oxidative stress, and inflammation, with HSP90AA1 being a key target, providing a novel therapeutic strategy for chemotherapy-associated cognitive impairment.…”

Percentages of dividing lymphocytes 72 hours after mitogenic stimulation. by Fanny Gaignier (541785)

“…(<b>B</b>) Percentages of dividing CD3⁺ T cells, CD3⁺CD8⁺ Tc cells and CD3⁺CD4⁺ Th cells in response to ConA. No significant difference was obtained for dividing T cells despite the decreases observed for the HU group compared to C mice.…”

Whole-Body Counter(WBC) and food radiocesium contamination surveys in Namie, Fukushima Prefecture by Yoichiro Hosokawa (339409)

“…Moreover, the radioactivity of seven items in these 10 items decreased from fiscal 2012 to fiscal 2015. Mushrooms had high radioactivity and were produced over a wide area.…”

Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia by Yong-jun Liu (5660170)

“…The proportion of Th17 cells at 7 days post-infection was decreased if Treg cells isolated from normal adult mice, but not Treg cells from the livers of mice with BA, were intraperitoneally transferred on day 5 of life. …”