Image_2_Relief of Cadmium-Induced Intestinal Motility Disorder in Mice by Lactobacillus plantarum CCFM8610.tif by Yang Liu (4829)

“…<p>Cadmium (Cd) is a toxic metal inducing a range of adverse effects on organs including liver and kidneys. …”

Image_1_MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.tif by Xilong Kang (2548195)

“…The overexpression of miR-5112 decreased inflammatory cytokine production, accompanied by a reduction of IKKγ in flagellin-stimulated BMDCs. …”

Image_1_Induction of Autophagy by Ursolic Acid Promotes the Elimination of Trypanosoma cruzi Amastigotes From Macrophages and Cardiac Cells.tif by María Cristina Vanrell (3924611)

“…To test this effect, the cells were infected with T. cruzi for 24 h and then treated with UA (5–10 µM). The data showed that UA significantly decreased the number of amastigotes found in infected cells in comparison with non-treated cells. …”

Image_4_Relief of Cadmium-Induced Intestinal Motility Disorder in Mice by Lactobacillus plantarum CCFM8610.tif by Yang Liu (4829)

“…<p>Cadmium (Cd) is a toxic metal inducing a range of adverse effects on organs including liver and kidneys. …”

Table_4_The Pathogenic Effects of Fusobacterium nucleatum on the Proliferation, Osteogenic Differentiation, and Transcriptome of Osteoblasts.XLS by Hui Gao (169623)

“…Whole-transcriptome analyses identified a total of 235 transcripts that were differentially expressed in all six time points, most of which were inflammation-related genes. …”

Variation in One Residue Associated with the Metal Ion-Dependent Adhesion Site Regulates αIIbβ3 Integrin Ligand Binding Affinity by Joel Raborn (468056)

“…Interestingly, mutations in the adjacent to MIDAS (ADMIDAS) of integrins α4β7 and αLβ2 increased the binding and adhesion abilities compared to the wild-type, while the same mutations in the α2β1, α5β1, αVβ3, and αIIbβ3 integrins demonstrated decreased ligand binding and adhesion. …”

DataSheet1_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Table_1_Initial Invasive or Conservative Strategy in Heart Failure With Preserved Ejection Fraction and Coronary Artery Disease.docx by Jun Gu (89637)

“…With a follow-up of 5 years, 378 (57.3%) in the invasive-strategy group and 403 (61.1%) in the conservative-strategy group reached the primary endpoint, and there was no significant difference in the rate of the primary endpoint (P = 0.162). …”

Image_3_Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients.TIF by Maximilianos Elkouris (175800)

“…Simultaneously, SNCA mRNA levels are increased in the nigra, while LRRK2 and PINK1 mRNA levels are decreased both in the nigra and the cerebellum of PD subjects compared to controls, indicating a possible correlation between the expression profile of the respective lncRNAs with their adjacent coding genes. …”

Image_2_The Pathogenic Effects of Fusobacterium nucleatum on the Proliferation, Osteogenic Differentiation, and Transcriptome of Osteoblasts.TIF by Hui Gao (169623)

“…Whole-transcriptome analyses identified a total of 235 transcripts that were differentially expressed in all six time points, most of which were inflammation-related genes. …”

Table_1_Global Characterization of Peripheral B Cells in Parkinson’s Disease by Single-Cell RNA and BCR Sequencing.xlsx by Pingping Wang (1485592)

“…Finally, we found a marked clonal expanded memory B cell population in PD patients, up-regulating both MHC II genes (HLA-DRB5, HLA-DQA2 and HLA-DPB1) and transcription factor activator protein 1 (AP-1), suggesting that the antigen presentation capacity of B cells was enhanced and B cells were activated in PD patients. …”

table_1.docx by Kamil Chwojnicki (3092397)

“…Introduction<p>Ischemic stroke (IS) still constitutes a serious problem for public health worldwide. …”

Table_1_MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.docx by Xilong Kang (2548195)

“…The overexpression of miR-5112 decreased inflammatory cytokine production, accompanied by a reduction of IKKγ in flagellin-stimulated BMDCs. …”

Decoding biomass recalcitrance: Dispersion of ionic liquid in aqueous solution and efficient extraction of lignans with microwave magnetic field by Yu Xia (8822)

“…The optimum hydrolysis conditions were 0.2 g of ionic liquid catalyst per 5.0 g of <i>S</i>. <i>chinensis</i> fruits, a microwave irradiation power of 600 W, and heating time of 12 min, which gave a yield of free-state biphenyl cyclooctene lignans of 4.12±0.37 mg g⁻¹. …”

<b>Canagliflozin-induced adaptive metabolism in bone</b> by Sher Bahadur Poudel (20686192)

“…Significant metabolic adaptations to CANA were evident as early as 1.5 months post-treatment, specifically in male mice. …”

Supplementary Material for: Age-Period-Cohort Analysis of Mortality from Ischemic Stroke Attributable to High Systolic Blood Pressure: Trends and 2030 Projections for Turkey and Eu... by figshare admin karger (2628495)

“…Introduction: High systolic blood pressure (HSBP) is a leading modifiable driver of the global ischemic stroke (IS) burden. …”

Image_1_Apolipoprotein-E deficiency leads to brain network alteration characterized by diffusion MRI and graph theory.JPEG by Margaret Caroline Stapleton (17437713)

“…<p>Late-onset Alzheimer’s disease (LOAD) is a major health concern for senior citizens, characterized by memory loss, confusion, and impaired cognitive abilities. …”

Diabetes and Risk of Parkinson's Disease: An Updated Meta-Analysis of Case-Control Studies by Lin Lu (5759)

“…</p><p>Conclusion</p><p>Evidence from case-control studies suggested that diabetic individuals may have a decreased incidence of PD despite significant heterogeneity. …”

Data_Sheet_1_Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis.PDF by Anita Balázs (3239238)

“…Secretory mucins MUC6 and MUC5B were upregulated in human, Muc6 in mouse CP. …”

Image_1_Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients.TIF by Maximilianos Elkouris (175800)

“…Simultaneously, SNCA mRNA levels are increased in the nigra, while LRRK2 and PINK1 mRNA levels are decreased both in the nigra and the cerebellum of PD subjects compared to controls, indicating a possible correlation between the expression profile of the respective lncRNAs with their adjacent coding genes. …”