Multiple-to-Multiple Relationships between MicroRNAs and Target Genes in Gastric Cancer by Yutaka Hashimoto (231668)

“…To find some groups of miRNAs that may synergistically regulate their targets in human gastric cancer (GC), we re-analyzed our previous miRNA expression array data and found that 50 miRNAs were up-regulated on treatment with 5-aza-2'-deoxycytidine in a GC cell line. The “TargetScan” miRNA target database predicted that some of these miRNAs have common target genes. …”

Correlation between intraocular pressure (IOP) and axial globe length biometric parameters in the various subgroups of the ED cohort. by Thomas Boillot (656368)

“…<p>(a-c) Correlation between IOP and axial globe length (AGL) in all EDs from the cohort: increasing IOP was significantly associated with decreasing AGL (<i>p</i> = 0.05, Spearman's test; a). …”

DataSheet1_Stranding of larval nase (Chondrostoma nasus L.) depending on bank slope, down-ramping rate and daytime.PDF by Simon Führer (13288143)

“…As a response parameter, we quantified stranding rates of different larval stages (III-IV and V) of common nase (Chondrostoma nasus L.). …”

DataSheet2_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

DataSheet4_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Image_1_Effect of Hulless Barley Flours on Dough Rheological Properties, Baking Quality, and Starch Digestibility of Wheat Bread.JPEG by Liwei Yu (5088008)

“…Furthermore, the hydrolysed starch rate in hulless barley-supplemented bread was decreased, compared with that in JM bread. Importantly, the contents of β-glucan, polyphenols and flavonoids in hulless barley-supplemented bread were 132.61–160.87%, 5.71–48.57%, and 25–293.75% higher than those in JM bread, respectively. …”

Table_1_Evolutionary history of genus Coptis and its dynamic changes in the potential suitable distribution area.xlsx by Yiheng Wang (5448683)

“…<p>The genus Coptis belongs to the Ranunculaceae family, containing 15 recognized species highly diverse in morphology. It is a conspicuous taxon with special evolutionary position, distribution pattern and medicinal value, which makes it to be of great research and conservation significance. …”

Supplementary file 1_Retinal features as predictive indicators for high myopia: insights from explainable multi-machine learning models.docx by Haohan Zou (15255107)

“…The mean curvature of the arteries >0.00063, diameter of vessels >55.2 um, curvature of the veins >0.00128, vertical diameter of the optic disc >1320 um, diameter of veins >58.5 um, and diameter of artery >47.1 um was associated with a decreased risk of HM.…”

Breeding ecology of Eurasian bullfinches <i>Pyrrhula pyrrhula</i> in an Iberian hedgerow habitat by Ángel Hernández (10512777)

“…The studied population occupied a hedgerow habitat in northwestern Spain. Individuals directly watched in the study area and details of these sightings were recorded over a six-year period, and a total of 56 nests were monitored. …”

Cordycepin prevents the esophageal stricture formation in the alkali-burn rat model by exerting anti-inflammatory and antifibrotic effects by Gulcin Ercan (5223101)

“…, proliferative and fibrotic factor fibroblast growth factor 2 (FGF2) and angiogenic factor vascular endothelial growth factor A (VEGFA) (p < 0.05). Conclusions The findings suggest that cordycepin has a complex multifactorial healing process in alkali-burned tissue, more successful than prednisolone in preventing the formation of esophageal strictures and may be used as a therapeutic agent in the acute phase of esophageal alkali-burn.…”

Image_2_MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.tif by Xilong Kang (2548195)

“…The overexpression of miR-5112 decreased inflammatory cytokine production, accompanied by a reduction of IKKγ in flagellin-stimulated BMDCs. …”

Image_2_Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis.jpeg by Anita Balázs (3239238)

“…Secretory mucins MUC6 and MUC5B were upregulated in human, Muc6 in mouse CP. …”

Characterization, Antioxidant and Antibacterial Potentials of Tamarindus indica L. Fruit Pulp Extract Loaded O/W Nanoemulsions by Sarunyoo Songkro (13778576)

“…The o/w nanoemulsions using a mixture of Tween 80 and Span 80 as an emulsifier (5%w/w) were prepared by a high pressure homogenization process. …”

Increased thoracic fluid content is associated with higher risk for pneumonia in patients undergoing maintenance hemodialysis by Lijuan Yan (335426)

“…Multivariate binary logistic analysis revealed that for each 1/KΩ increase in TFC and 1 increase in neutrophil-to-lymphocyte ratio (NLR), the risk of the development of pneumonia increased by 3.1% (<i>p</i> ˂ 0.01) and 7.2% (<i>p</i> = 0.035), respectively, whereas for each 1 g/L increase in hemoglobin and 1 g/L increase in serum albumin, the risk of the development of pneumonia decreased by 1.3% (<i>p</i> = 0.034) and 5% (<i>p</i> = 0.048), respectively.…”

DataSheet1_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

Image_1_Untargeted metabolomics reveals the alteration of metabolites during the stewing process of Lueyang black-bone chicken meat.pdf by Ling Wang (56577)

“…During the heating process, the abundances of Ser, Ala, Tyr, niacinamide, galactose, guanosine 3′-monophosphate and inosine 5′-monophosphate in chicken meat significantly decreased and were partially dissolved in the soup. …”

Image_4_Phenotype and function of MAIT cells in patients with alveolar echinococcosis.tif by Jintian Li (11679448)

“…Circulating MAIT exhibited activation and exhaustion phenotypes, and intrahepatic MAIT cells showed increased activation phenotypes with increased IFN-γ and IL-17A, and high expression of CXCR5 chemokine receptor. …”

Image_1_Integrative metagenomic and lipidomic analyses reveal alterations in children with obesity and after lifestyle intervention.jpeg by Chunyan Yin (5384525)

“…Correlation analyses indicated a significant positive relationship between ChE(2:0) levels and both with s-Lachnospiraceae_bacterium_TF09-5 and fasting glucose levels. …”

Table_6_Transcriptome in Combination Proteome Unveils the Phenylpropane Pathway Involved in Garlic (Allium sativum) Greening.XLSX by Jinxiang Wu (475283)

“…The greening phenomenon of garlic severely decreases the quality of garlic and hinders garlic processing. …”

Table_4_Evolutionary history of genus Coptis and its dynamic changes in the potential suitable distribution area.xlsx by Yiheng Wang (5448683)

“…<p>The genus Coptis belongs to the Ranunculaceae family, containing 15 recognized species highly diverse in morphology. It is a conspicuous taxon with special evolutionary position, distribution pattern and medicinal value, which makes it to be of great research and conservation significance. …”