Three-year safety and two-year effectiveness of etanercept in patients with rheumatoid arthritis in Japan: Results of long-term postmarketing surveillance by Hisashi Yamanaka (137140)

“…Mean baseline DAS28-4/ESR for the 581 patients included in effectiveness analysis was 5.42, which decreased to 3.32 at 2 years. Eighty-two percent of patients achieved a moderate/good response at 2 years.…”

DataSheet1_Vegetation Dynamics and its Response to Climate Change in the Yellow River Basin, China.docx by Cun Zhan (12454887)

“…Results indicated that the annual NDVI in the YRB decreased spatially from southeast to northwest, and peaked in August. …”

Polarity-Induced Reactive Wetting: Spreading and Retracting Sessile Water Drops by William S. Y. Wong (2795890)

“…Drops contacting the transition spread before retracting, occurring over the time scale of a few seconds. This phenomenon contradicts current understanding, exhibiting a uniquely (1) decreasing advancing contact angle and (2) increasing receding contact angle. …”

image1_Allergic Asthma-Induced Cognitive Impairment is Alleviated by Dexamethasone.pdf by Mengli Ren (6707078)

“…<p>Allergic asthma is a typical chronic inflammatory disease of respiratory tract. …”

Table_2_Omics-Based Mechanistic Insight Into the Role of Bioengineered Nanoparticles for Biotic Stress Amelioration by Modulating Plant Metabolic Pathways.DOCX by Madhuree Kumari (3699274)

“…The particles reduced disease severity by 70–80% at 5 μg/ml without showing phytotoxicity. It elicited plant immunity by a significant reduction in reactive oxygen species (ROS), decreases in stress enzymes by 0.6–19.8-fold, and emergence of autophagy. …”

NPB304 affected P-gp function and increased paclitaxel accumulation in P-gp-overexpressing resistant cells and tumor tissue. by Mei Mei (610571)

“…(C) NPB304 treatment promoted bidirectional permeability but decreased the efflux ratio of paclitaxel in a Caco-2 monolayer model. …”

Factors associated to the frailty phenotype components among hospitalized elderly patients by Lorraine Cristina Silva (6485201)

“…The following associated factors were identified: self-report of exhaustion and/or fatigue [depression indicative (OR: 3.12; CI: 1.69-5.75)]; decreased muscle strength [advanced age (OR:2.20; CI: 1.40-3.47); absence of partner (OR: 1.86, CI: 1.023.39); inability to perform basic (OR: 2.38; CI: 1.27-4.44) and instrumental (OR: 2.53; CI: 1.29-4.97) activities of the daily living]; slow gait speed [women (OR:2.13; CI:1.16-3.92), advanced age (OR:2.90; CI:1.82-4.61), inability to perform instrumental activities of the daily living (OR:2.08; CI:1.14-3.77); and low level of physical activity [advanced age (OR: 1.57; CI: 1.01-2.44)]. …”

Integrative Proteomics and Metabolomics Analysis of Insect Larva Brain: Novel Insights into the Molecular Mechanism of Insect Wandering Behavior by Yi Li (1144)

Novel PPAR Pan Agonist, ZBH Ameliorates Hyperlipidemia and Insulin Resistance in High Fat Diet Induced Hyperlipidemic Hamster by Wei Chen (23863)

“…By incorporating the key pharmacophore of fibrates into the natural scaffold of resveratrol, a novel structural compound ZBH was constructed. …”

Image_4_Identification, Characterization, and Expression Profile Analysis of the mTERF Gene Family and Its Role in the Response to Abiotic Stress in Barley (Hordeum vulgare L.).JPE... by Tingting Li (10553)

“…In this study, we identified 60 mTERFs in the barley genome (HvmTERFs) through a comprehensive search against the most updated barley reference genome, Morex V2. …”

DataSheet_1_Coix Seed Oil Exerts an Anti–Triple-Negative Breast Cancer Effect by Disrupting miR-205/S1PR1 Axis.zip by Ting Fang (155126)

“…<p>Coix Seed Oil (CSO) possesses a wide range of pharmacological activities. Kanglaite Injection, a commercial product of CSO, has been used clinically as an anticancer drug in China for decades. …”

Data Sheet 1_Impact of high-altitude exposure on cerebral lobe functions in climbers: insights from the Nepali Himalayas.pdf by Sunil Dhungel (21449354)

“…Cognitive function tests (CFT) assessed cerebral lobe function at altitudes ranging from 800 to 5,500 meters using a non-invasive neuropsychological battery.…”

Table_3_Ontogeny and brooding strategy of the early Cambrian arthropod Isoxys minor from the Qingjiang biota.XLSX by Jiaxin Ma (3847726)

“…<p>†Isoxys is a worldwide distributed bivalved arthropod known almost exclusively from Cambrian Burgess Shale-type Lagerstätten. …”

Table_4_Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids.xls by Qian Zhuang (621842)

“…GPs increased the hepatic expression of genes encoding the cytochrome P450 (Cyp) enzymes Cyp7a1, Cyp7b1, and Cyp8b1, while decreasing the hepatic expression of genes encoding the adenosine triphosphate-binding cassette (Abc) transporters Abcg5 and Abcg8. …”

Inhibition of PI3K/Akt activity reduces phosphorylation of GSK3β while increases HB9 motor neuron differentiation. by Luis Ojeda (208583)

“…<p>(A–B) Effect of PI3K/Akt inhibition on GSK3β phosphorylation in hNSCs primed for 40 minutes in either ELL (A) or FL (B). …”

Data_Sheet_2_Ontogeny and brooding strategy of the early Cambrian arthropod Isoxys minor from the Qingjiang biota.PDF by Jiaxin Ma (3847726)

“…<p>†Isoxys is a worldwide distributed bivalved arthropod known almost exclusively from Cambrian Burgess Shale-type Lagerstätten. …”

Data_Sheet_1_Ontogeny and brooding strategy of the early Cambrian arthropod Isoxys minor from the Qingjiang biota.pdf by Jiaxin Ma (3847726)

“…<p>†Isoxys is a worldwide distributed bivalved arthropod known almost exclusively from Cambrian Burgess Shale-type Lagerstätten. …”

Mouse Strain-Specific Differences in <i>Irf3</i> mRNA and Protein Levels by Oleg Garifulin (273081)

“…<div><p>(A) The majority of C57BL/6ByJ BMM <i>Irf3</i> transcripts retain intron 5 (upper band), whereas in both C57BL/6J and BALB/cByJ strains most of <i>Irf3</i> pre-mRNA is properly spliced.…”

Functional Characterization of the Tau Class Glutathione-<i>S</i>-Transferases Gene (<i>SbGSTU</i>) Promoter of <i>Salicornia brachiata</i> under Salinity and Osmotic Stress by Vivekanand Tiwari (650298)

“…The glutathione-S-transferase (GST) enzymes play a significant role to detoxify these toxins and help in excretion or sequestration of them. …”

Data Sheet 1_Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells.docx by Na Tian (296333)

“…Background<p>Adjuvant-induced arthritis (AIA) serves as a classic model for rheumatoid arthritis (RA), typified by inflammatory cell infiltration and joint damage. …”