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101681
Table_2_Relief of Cadmium-Induced Intestinal Motility Disorder in Mice by Lactobacillus plantarum CCFM8610.docx
Published 2020“…<p>Cadmium (Cd) is a toxic metal inducing a range of adverse effects on organs including liver and kidneys. …”
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101682
Table 4_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…This study aimed to evaluate the diagnostic utility of speckle tracking echocardiography (STE)-derived strain parameters in patients with frequent PVCs and to identify associated risk factors for early myocardial impairment.</p>Methods<p>A total of 258 patients with monomorphic PVCs and a PVC burden >5% on 24 h Holter monitoring were enrolled, along with 80 age- and sex-matched healthy controls. …”
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101683
Silencing BRE Expression in Human Umbilical Cord Perivascular (HUCPV) Progenitor Cells Accelerates Osteogenic and Chondrogenic Differentiation
Published 2013“…<i>BRE</i>-silencing negatively regulated <i>OCT4</i>, <i>FGF5</i> and <i>FOXO1A</i>. <i>BRE</i>-silencing also altered the expression of epigenetic genes and components of the TGF-β/BMP and FGF signaling pathways which are crucially involved in maintaining stem cell self-renewal. …”
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101684
Table_6_The Pathogenic Effects of Fusobacterium nucleatum on the Proliferation, Osteogenic Differentiation, and Transcriptome of Osteoblasts.XLSX
Published 2020“…Whole-transcriptome analyses identified a total of 235 transcripts that were differentially expressed in all six time points, most of which were inflammation-related genes. …”
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101685
DataSheet8_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau...
Published 2022“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”
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101686
DataSheet10_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopa...
Published 2022“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”
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101687
Image_2_Phenotype and function of MAIT cells in patients with alveolar echinococcosis.tif
Published 2024“…Circulating MAIT exhibited activation and exhaustion phenotypes, and intrahepatic MAIT cells showed increased activation phenotypes with increased IFN-γ and IL-17A, and high expression of CXCR5 chemokine receptor. …”
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101688
Image_1_Phenotype and function of MAIT cells in patients with alveolar echinococcosis.tif
Published 2024“…Circulating MAIT exhibited activation and exhaustion phenotypes, and intrahepatic MAIT cells showed increased activation phenotypes with increased IFN-γ and IL-17A, and high expression of CXCR5 chemokine receptor. …”
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101689
Image_1_Case report: Spontaneous lens absorption after the implantation of an implantable collamer lens.TIF
Published 2023“…The patient had undergone binocular ICL implantation for refractive correction of high myopia 1.5 years prior. Approximately 10 months later, he experienced a sudden loss of vision and pain in his left eye, which resolved spontaneously the next day without any treatment. …”
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101690
Image_6_Apolipoprotein-E deficiency leads to brain network alteration characterized by diffusion MRI and graph theory.JPEG
Published 2023“…<p>Late-onset Alzheimer’s disease (LOAD) is a major health concern for senior citizens, characterized by memory loss, confusion, and impaired cognitive abilities. …”
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101691
Image_1_D-Serine Contributes to Seizure Development via ERK Signaling.tif
Published 2019“…L-aspartic acid β-hydroxamate (LaaβH), an inhibitor of SR, significantly prolonged the latencies of seizures, shortened the durations of seizures, and decreased the total EEG power in rats. In contrast, D-amino acid oxidase inhibitor 5-chlorobenzo[d]isoxazol-3-ol (CBIO), which can increase D-serine levels, showed the opposite effects. …”
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101692
Table_1_Effect of red meat, vegetable, tobacco, and alcohol consumption on national cancer mortality index: Data from 1989 to 2013 in 37 developed countries.XLSX
Published 2022“…According to the FEM, cancer death had statistically significant associations with education level (Coef = −0.022, P = 0.009), total health expenditure (Coef = −0.049, P = 0.000), aging rate (Coef = −0.178, P = 0.000), tobacco consumption (Coef = 0.096, P = 0.000), RM consumption (Coef = 0.107, P = 0.000), and vegetable consumption (Coef = −0.034, P = 0.000). A similar trend was also observed in the 3 and 5-year lagged models. …”
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101693
Image_1_D-Serine Contributes to Seizure Development via ERK Signaling.tif
Published 2025“…L-aspartic acid β-hydroxamate (LaaβH), an inhibitor of SR, significantly prolonged the latencies of seizures, shortened the durations of seizures, and decreased the total EEG power in rats. In contrast, D-amino acid oxidase inhibitor 5-chlorobenzo[d]isoxazol-3-ol (CBIO), which can increase D-serine levels, showed the opposite effects. …”
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101694
DataSheet2_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau...
Published 2022“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”
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101695
Table 3_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…This study aimed to evaluate the diagnostic utility of speckle tracking echocardiography (STE)-derived strain parameters in patients with frequent PVCs and to identify associated risk factors for early myocardial impairment.</p>Methods<p>A total of 258 patients with monomorphic PVCs and a PVC burden >5% on 24 h Holter monitoring were enrolled, along with 80 age- and sex-matched healthy controls. …”
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101696
Table_2_Plant Community Traits Respond to Grazing Exclusion Duration in Alpine Meadow and Alpine Steppe on the Tibetan Plateau.DOCX
Published 2022“…<p>Grazing exclusion has been a primary ecological restoration practice since the implement of “Returning Grazing Land to Grassland” program in China. …”
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101697
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101698
DataSheet_1_Gut microbiome variation in pulmonary TB patients with diabetes or HIV comorbidities.pdf
Published 2023“…</p>Results<p>Compared to the healthy controls, the gut microbiome of all the TB cohorts was characterized by a significant decreased alpha diversity and significant compositional changes. …”
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101699
Image_1_Ductal Mucus Obstruction and Reduced Fluid Secretion Are Early Defects in Chronic Pancreatitis.jpeg
Published 2018“…Secretory mucins MUC6 and MUC5B were upregulated in human, Muc6 in mouse CP. …”
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101700
Image 1_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study....
Published 2025“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”