Table1_Case Report: C3 deficiency in two siblings.docx by Agustín Bernacchia (19204375)

“…Deficiencies in complement proteins, particularly C3, can lead to severe and recurrent infections as well as immune complex disorders. Here, we present a case report of two siblings with total C3 deficiency resulting from compound heterozygous mutations in C3 (NM_000064.4): c.305dup; [p.Asn103GlnfsTer66] and c.1269 + 5G>T, previously unreported in C3-related diseases. …”

DataSheet_1_Changes of androgen and corticosterone metabolites excretion and conversion in cystic fibrosis.pdf by Rafał Podgórski (11606097)

“…We have also found the increased conversion activity of 11-oxyganated steroids by 5a-reductase in backdoor pathway. Levels of the most potent and vital androgens (testosterone and dihydrotestosterone) are comparable in both groups. …”

Bioinformatics analysis. by Charlotte Repton (3250161)

“…<p>(A) Physical protein-protein interactions known among 47 proteins that significantly increased their microtubule binding under 14-3-3 inhibition (the fold change >1.5 and p<0.05; the boxed area in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009995#pgen.1009995.g001" target="_blank">Fig 1C</a>). …”

NOMID mice exhibit stunted skeletal growth and reduced bone mass. by Sheri L. Bonar (168963)

“…<p>X-ray radiography (<i>A</i>), DXA (<i>B</i>) or μCT analysis of the femur (<i>C, E</i>–<i>H</i>) of NOMID and WT mice at age P13. …”

Iron-Responsive miR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin by Carolyn Sangokoya (399189)

“…Conversely, both inhibition of miR-485-3p activity and mutation of the miR-485-3p target sites on the FPN 3′UTR are able to relieve FPN repression and lead to decreased cellular iron levels. Together, these findings support a model that includes both IRPs and microRNAs as iron-responsive post-transcriptional regulators of FPN. …”

The effect of tachykinin receptor antagonists, when perfused with substance P by Kerrie N Wease (12951)

“…The neurokinin-2 receptor antagonist MDl29,913 (12 μM, n = 4) and the NK-3 antagonist [Trp, β-Ala]-neurokinin A (4–10) (5 μM, n = 3), had no significant effecton the action of substance P (b) Example synaptic response recorded from 3 representative slices showing control responses (top row), responses recorded in the presence of substance P (middle row), and responses recorded in the presence of substance P and the antagonist (bottom row). …”

In vitro analysis on RECQL1 expression. by Sakiko Sanada (443800)

“…Cell viability decreased with time after siRNA treatment. RECQL1-siRNA significantly inhibited the proliferation of a wide range of OC cell lines in accordance with the reduction of RECQL1 mRNA (shown as histograms). …”

TENET 2.0 pictoral workflow. by Daniel J. Mullen (9375294)

“…Probes intersecting both of these regions are subsetted to those >1.5kb from GENCODE v22-annotated transcription start sites to avoid promoter regions. …”

DataSheet_1_Short-term effects of Chlorhexidine mouthwash and Listerine on oral microbiome in hospitalized patients.pdf by Tsunglin Liu (33873)

“…Before and after gargling the mouthwash twice a day for 5-7 days, oral bacteria were examined using a 16S rDNA approach.…”

Image1_Pilot study shows skin-to-skin care with parents improves heart rate variability in preterm infants in the neonatal intensive care unit.jpeg by Erin Swieter (16999362)

“…SDNN decreased from a median of 10.44 ms before the session to 6.70 ms after being placed back in bed (p < 0.05), with RMSSD decreasing from a median of 6.80 ms before the session to 4.32 ms while being held at the end of 30 min (p < 0.05).…”

Excel raw data. by Michael Getie (12400923)

“…<div><p>Background</p><p>Antimicrobial resistance is a major public health problem worldwide, particularly in developing countries. …”

The growth stage before nitrogen starvation and the availability of vacuolar hydrolases impacted the accumulation of autophagosome clusters (APCs) in <i>vps21Δ</i> cells. by Zulin Wu (4451572)

“…PhC, phase contrast; scale bars in panels A, C, and E, 5 μm; arrows, APCs, and OD, OD₆₀₀. …”

STAP model of TF-DNA binding. by Qiong Cheng (440773)

“…The site-specific terms q_A, q_B are proportional to TF concentration, so a doubling of concentration will change (q_A = 0.9, q_B = 0.5) to (q_A = 1.8, q_B = 1.0), and this will impact the predicted occupancy (OCC = 0.807 to OCC = 1.143), but does not double the prediction, due to saturation effects. …”

New types of behavioral inference from the FLIC system. by Jennifer Ro (590372)

“…Flies with loss of function in the trehalose receptor, <i>ΔGr5a</i>, were significantly delayed in their first meal of a liquid trehalose food compared with control animals (log-rank test). …”

Systematic review of microRNAs in human acute kidney injury by Adrianna Douvris (4113439)

“…Overall study quality was fair (median 5/9, range 2-8 points).</p> <p>Dysregulated miRNAs, particularly miR-21, have potential as AKI biomarkers. …”

Data_Sheet_1_Predictors and Changes in Paternal Perinatal Depression Profiles—Insights From the DREAM Study.PDF by Susan Garthus-Niegel (3555482)

“…We found that rates of paternal depression symptoms decreased with 9% during pregnancy to 5% at 8 weeks postpartum. …”

MHD effects on nanofluid with energy and hydrothermal behavior between two collateral plates application of new semi analytical technique by Sheikholeslami, Mohsen

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Microarray analysis in HDFs reveal that MALAT1-depletion reduces the expression of genes involved in cell cycle progression. by Vidisha Tripathi (393132)

“…<p>(A) Top significant biological processes for genes whose transcript levels are reduced (Z ratio ≥2.5) in MALAT1-depleted fibroblasts. …”

Telomeric doublets following porcine iPS generation. by Guangzhen Ji (464330)

“…(D) Frequency of telomere doublets decreased in 68P9, 102P10 and KSR4P9 with exo-genes silencing or partial silencing, compared with progenitor LFFP5. …”

Real-time PCR analysis of expression of mRNAs encoding ameloblast markers in primary cultures of ameloblasts. by Kan Saito (715965)

“…<p>A. Wild type (WT) ameloblasts were cultured with RGD or RAD peptide for 0 to 72 hours. …”