Prevention of mIPSC amplitude potentiation by blockers of GABA- and glutamate-uptake. by Kristin Hartmann (52443)

“…(B) Effect of NNC-711 (solid line) illustrated by cumulative amplitude distribution curves of the cells depicted in A. Curve is situated between distributions from control (left) and drug-free stimulated cell (right; dashed lines; data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0002979#pone-0002979-g001" target="_blank">Fig. 1A, B</a>). …”

Quantitative Proteomic Analysis of Niemann-Pick Disease, Type C1 Cerebellum Identifies Protein Biomarkers and Provides Pathological Insight by Stephanie M. Cologna (125652)

“…Translating our findings from the murine model to patients, we confirm altered expression of glutathione s-transferase α, superoxide dismutase, and FABP3 in cerebrospinal fluid of NPC1 patients relative to pediatric controls. A subset of NPC1 patients on miglustat, a glycosphingolipid synthesis inhibitor, showed significantly decreased levels of FABP3 compared to patients not on miglustat therapy. …”

Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1 by Tara Rao (395307)

“…They competitively antagonized the cJun–cFos coiled-coil interaction. Truncating a Jun-based peptide from 37 to 22 residues decreased the binding enthalpy for cJun by ∼9 kcal/mol, but this was compensated by increased conformational entropy (TΔS ≤7.5 kcal/mol). …”

Blue Phosphorescent <i>trans</i>-N-Heterocyclic Carbene Platinum Acetylides: Dependence on Energy Gap and Conformation by James D. Bullock (7491032)

“…Ultrafast transient absorption spectroscopy reveals a fast relaxation (∼5 ps) that may also be due to aryl acetylide ring torsional relaxation in the triplet excited state.…”

Data Sheet 1_Assessing the importance of acoustic backscatter and bottom trawling impact as predictor variables for mapping deep sea coral reefs.docx by Christopher Berry (6418166)

“…The reduction in extent of coral VME area was dependent on the probability threshold of habitat suitability used in the model, decreasing by 20.44%–26.07% following trawling across a range of thresholds from 0.5–0.85. …”

Table_1_Integrated Transcriptome Analysis and Single-Base Resolution Methylomes of Watermelon (Citrullus lanatus) Reveal Epigenome Modifications in Response to Osmotic Stress.xlsx by Fangming Zhu (1695271)

“…The effect of methylation level on the expression properties of inositol and its related genes was further confirmed by application of DNA methylation inhibitor 5-azacytidine. These results provide a preliminary insight into the altered methylation levels of watermelon cells in response to osmotic stress and suggest a new mechanism that how watermelon cells adapt to osmotic stress.…”

Data_Sheet_1_Investigation of the growth performance, blood status, gut microbiome and metabolites of rabbit fed with low-nicotine tobacco.docx by Changliang Jing (5106365)

“…The objective of this study was to evaluate the effects of dietary addition of low-nicotine tobacco (LNT) on the growth performance, blood status, cecum microbiota and metabolite composition of meat rabbits. A total of 80 Kangda meat rabbits of similar weight were assigned randomly as four groups, and three of them were supplemented with 5%, 10%, and 20% LNT, respectively, with the other one fed with basal diet as control group. …”

uORFs overlapping CDS mediate the highest repressive potential. by Philipp Fervers (5616980)

“…The regression lines slope can be employed as a measure, how effective overweighting a uORF correlates to protein output control. …”

Representative karyotypes of hybrid biotypes after GISH and/or DAPI/Giemsa staining. by Zuzana Majtánová (848096)

“…Chromosomes were arranged in a decreasing size order and classified in four morphological groups: metacentric (m), submetacentric (sm), subtelocentric (st) and acrocentric (a). …”

Table_4_Effect of acupuncture on the opening time of implantation window and endometrial receptivity in controlled ovarian hyperstimulation rats during peri-implantation period.xls... by Runan Hu (9989607)

“…</p>Methods<p>Experimental rats were randomly divided into normal group (N), model group (M) and acupuncture group(A), and samples were collected on Day 4, 5 and 6 after mating. …”

Library Enabling Annotation of Botanical Natural Products (LEAFBot): An Open-Access Library of Mass Spectrometry Fragmentation Spectra for Plant Metabolites by Victoria M. Anderson (12412672)

Data_Sheet_1_Integrated Transcriptome Analysis and Single-Base Resolution Methylomes of Watermelon (Citrullus lanatus) Reveal Epigenome Modifications in Response to Osmotic Stress.... by Fangming Zhu (1695271)

“…The effect of methylation level on the expression properties of inositol and its related genes was further confirmed by application of DNA methylation inhibitor 5-azacytidine. These results provide a preliminary insight into the altered methylation levels of watermelon cells in response to osmotic stress and suggest a new mechanism that how watermelon cells adapt to osmotic stress.…”

Zn_<i>x</i>Mn_1–<i>X</i>Fe₂O₄@SiO₂:<i>z</i>Nd³⁺ Core–Shell Nanoparticles for Low-Field Magnetic Hyperthermia and Enh... by Marcus Vinícius-Araújo (10096489)

“…Additionally, as a potential nanothermometer, with excitation around 800 nm and emission at the second biological window, the thermal sensitivity of the system was found to be ∼1.1 % K^–1 at 300 K (27 °C), ∼ 1.4% K^–1 at 316 K (43 °C), and ∼1.5% K^–1 at 319 K (46 °C). …”

Zn_<i>x</i>Mn_1–<i>X</i>Fe₂O₄@SiO₂:<i>z</i>Nd³⁺ Core–Shell Nanoparticles for Low-Field Magnetic Hyperthermia and Enh... by Marcus Vinícius-Araújo (10096489)

“…Additionally, as a potential nanothermometer, with excitation around 800 nm and emission at the second biological window, the thermal sensitivity of the system was found to be ∼1.1 % K^–1 at 300 K (27 °C), ∼ 1.4% K^–1 at 316 K (43 °C), and ∼1.5% K^–1 at 319 K (46 °C). …”

Characteristics and findings of all studies included (n = 72). by Isabella Eckerle (381546)

“…</p>5<p>after 3rd dose, controls received a different vaccination scheme compared to SOT recipients (one vs. two doses of vaccine, respectively).…”

Zn_<i>x</i>Mn_1–<i>X</i>Fe₂O₄@SiO₂:<i>z</i>Nd³⁺ Core–Shell Nanoparticles for Low-Field Magnetic Hyperthermia and Enh... by Marcus Vinícius-Araújo (10096489)

“…Additionally, as a potential nanothermometer, with excitation around 800 nm and emission at the second biological window, the thermal sensitivity of the system was found to be ∼1.1 % K^–1 at 300 K (27 °C), ∼ 1.4% K^–1 at 316 K (43 °C), and ∼1.5% K^–1 at 319 K (46 °C). …”

Passive-transfer of monoclonal antibodies (mab) and protection from H1N1 challenge. by Dustin M. McCraw (16892354)

“…<p>(A) Survival curves for mice that were intranasally challenged with H1N1 virus 24 hours after intraperitoneally (IP) transfer of mAb-11, mAb-49, mAb-63, mAb-67 and mAb-85 at doses of 17.5 mg/kg. …”

Supplementary materials for PhD thesis “The Origin of Basaltic Lava Flow Textures” by Marie-Noëlle Guilbaud (2843387)

“…It is estimated that fluid lava was transported from the vent to the most distal active front, 60 km from the vent, with cooling rates of < 0.5°C/km. Young lava flow-fields in the Reykjanes Peninsula (Iceland), and some flows from the flood basalts of the Columbia River Province (USA), have surface and internal structures intermediate between rubbly pāhoehoe and 'a'ā. …”

3D-real IR MRI scans of patient no. 14 (Table 1) with right MD. by Anquan Peng (9585084)

“…(E) Audiogram showing that the mean hearing threshold of air conduction (0.25, 0.5, 1.0 and 2.0 KHz) decreased from 55 dB before to 26.3 dB after surgery. …”

Table_1_Anti-Migratory Effect of Dipotassium Glycyrrhizinate on Glioblastoma Cell Lines: Microarray Data for the Identification of Key MicroRNA Signatures.docx by Gabriel Alves Bonafé (6740750)

“…In addition, DPG treatment led to a 100% reduction in sphere formation. The qPCR results in U251 and U138MG cells showed that DPG increased miR-4443 (2.44 vs. 1.11, p-value = 0.11; 8.27 vs. 1.25, p-value = 0.04) and miR-3620 expression (1.66 vs. 1.00, p-value = 0.03; 8.47 vs. 1.01, p-value = 0.03) and decreased CD209 (0.44 vs. 1.10, p-value = 0.03; 0.49 vs. 1.07, p-value = 0.04) and TNC (0.20 vs. 1.03, p-value = 0.001; 0.39 vs. 1.06, p-value = 0.01) mRNA levels compared to controls. …”