The Ih current switches the type of excitability of the DA neuron to type II. by Ekaterina O. Morozova (3386927)

“…In C1, spiking is blocked as Iapp decreases through the LC Fold bifurcation. If Iapp increases through the same interval, the LC Fold bifurcation stays unnoticed because the equilibrium state remains stable, and only after the A-H bifurcation, spiking emerges. …”

Controlling the pro-angiogenic activity of TEM from breast cancer patients. by Nicolas Guex (117459)

“…Shown are cumulated data (C, D) or representative results (A and B) of 3 to 5 experiments. Significant variations (* P < 0.05, T test).…”

Image_2_Increased Reactive Oxygen Species and Cell Cycle Defects Contribute to Anemia in the RASA3 Mutant Mouse Model scat.JPEG by Emily S. Hartman (5339009)

“…Surprisingly, apoptosis is significantly decreased in the scat bone marrow at the proerythroblastic (15.3%; p = 0.004), polychromatophilic (8.5%; p = 0.01), and orthochromatic (4.2%; p = 0.02) stages. …”

Downstream element mutations affect MHC class I promoter activity <i>in Vitro</i>. by Namhoon Lee (235410)

“…<p><b>A) Mutation of the downstream elements decreases MHC class I promoter activity </b><b><i>in vitro</i></b><b>. …”

Schematic representation of c-Myc regulating cell proliferation and controlling cell fate in BASCs through both transcriptional and post-transcriptional pathways. by Jie Dong (12143)

“…The model (from our work and others) depicts c-Myc regulating downstream gene expression through two distinct mechanisms. 1) Transcriptional level: c-Myc directly regulates mRNA transcription with its partner Max through c-Myc/Max binding sites in the 5′-flanking promoter region of target genes. 88 genes were identified as potential downstream genes through a position weight matrix based method in conjunction with changes in mRNA level. 2) Post-transcriptional level: c-Myc indirectly regulates mRNA and protein expression through miRNAs. …”

Weak magnetic fields disturb cytoskeleton reassembly after nocodazole exposure, and influence actin polymerization. by Abasalt Bahrami (21989867)

“…The median alignment level for the nocodazole-disrupted cells under the ambient field (14.5) is 1.6 that of the nocodazole-disrupted cells under the applied magnetic field (8.7), with a p = 0.0278 0.05 indicated with a star. …”

Supporting Information. by Segni B. Ligaba (695899)

“…<i>I</i>, FACS with propidium iodide (<i>x-axis</i>) and a FITC conjugated annexin V antibody (<i>Y-axis</i>). …”

Image_1_Increased Reactive Oxygen Species and Cell Cycle Defects Contribute to Anemia in the RASA3 Mutant Mouse Model scat.JPEG by Emily S. Hartman (5339009)

“…Surprisingly, apoptosis is significantly decreased in the scat bone marrow at the proerythroblastic (15.3%; p = 0.004), polychromatophilic (8.5%; p = 0.01), and orthochromatic (4.2%; p = 0.02) stages. …”

Evolution of diabetes in Brazil: prevalence data from the 2013 and 2019 Brazilian National Health Survey by Rodrigo Citton Padilha dos Reis (12740955)

“…Drivers of this rise include increase in size (9.9%) and aging (1.8%) of the Brazilian population, and to all other factors, including increased case-detection and incidence, as well as decreased diabetes mortality (24.7%). Main correlates of greater prevalence - adjusted by the Poisson regression with robust variance - were older age (PR = 27.2, 95%CI: 1.2-42.9 for ≥ 65 years vs. 18-24 years), hypertension (PR = 2.6, 95%CI: 2.4-2.8 vs. normotension), and obesity (PR = 2.3, 95%CI: 2.1-2.5 vs. …”

Influence of the Contact Area on the Current Density across Molecular Tunneling Junctions Measured with EGaIn Top-Electrodes by Philipp Rothemund (1419079)

“…Measurements of current density, <i>J</i>(<i>V</i>), across SAMs of decanethiolate on silver demonstrate that <i>J</i>(<i>V</i>) increases with <i>A</i>_g when the contact area is small (<i>A</i>_g < 1000 μm²), but reaches a plateau between 1000 and 4000 μm², where <i>J</i>(0.5 V) ≈ 10^{–0.52±0.10} A/cm². …”

Figure S1 - The Association of Cysteine with Obesity, Inflammatory Cytokines and Insulin Resistance in Hispanic Children and Adolescents by Amany K. Elshorbagy (137193)

“…Common to all 5 knockouts is decreased plasma cyste(i)ne <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Kendig1" target="_blank">[3]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Lieberman1" target="_blank">[46]</a> or tCys <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Gupta1" target="_blank">[1]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Teng2" target="_blank">[6]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044166#pone.0044166-Mani1" target="_blank">[45]</a>. …”

HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy by Alexander Lind (5221088)

“…Among subjects with the <i>HLA</i>-<i>DRB5*01</i>:<i>01</i>:<i>01-DRB1*15</i>:<i>01</i>:<i>01-DQA1*01</i>:<i>02-DQB1*06</i>:<i>02</i> haplotype, a second <i>DRB4*01</i>:<i>03</i>:<i>01-DRB1*04</i>:<i>01</i>:<i>01-DQA1*03</i>:<i>02//*03</i>:<i>03</i>:<i>01-DQB1*03</i>:<i>01</i>:<i>01</i> haplotype (<i>p</i> = 2.02E^-2), but not homozygosity for <i>DRB1*15</i>:<i>01</i>:<i>01-DQB1*06</i>:<i>02</i>:<i>01</i> (<i>p</i> = 7.49E^-1) conferred association to NT1. …”

Results from the first culturally tailored, multidisciplinary diabetes education in Lebanese adults with type 2 diabetes: effects on self-care and metabolic outcomes by Sukkarieh-Haraty, Ola

“…This pilot-study tested the effect of culturally-tailored education targeting diabetes selfcare on glycemia and cardiovascular risk factors of Lebanese with type 2 diabetes mellitus (T2DM) (n = 27; Age: 61 ± 10 yrs, 59% males, HbA1c: 8.98 ± 1.38%). Results: Diabetes self-care (Diet, Self-Monitoring Blood Glucose and foot care) improved after 6 months, which was reflected in a significant drop in glycemic levels (HbA1c:-0.5%; FPG: − 38 mg/dl), and cholesterol/HDL ratio (4.45 ± 1.39 vs. 4.06 ± 1.29). …”
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Supplementary Tables from ER⁺ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors by Angel L. Guerrero-Zotano (7063892)

“…A decreased gene expression translates into a geometric mean change < 1 . …”

Developmental changes in percentage of EEG total power within the delta and theta frequency ranges during vigilance states of the neonatal mouse. by Nicholas Rensing (3686332)

“…<p>(<b>A</b>) During wakefulness, percentage of delta (1-4Hz) in EEG decreases until P17 and percent theta (4–8.5Hz) increases starting at P14. p<0.001, compared to ***P21; ### P17; ◆◆◆ P14; p<0.01 compared to ## P17; p<0.05 compared to ^{<b><i>&</i></b>}P12 by one-way repeated measures ANOVA with Tukey; n = 8–9 mice per group. …”

Negative regulation of <i>sNPF/NPY</i> by insulin signaling. by Seung-Hyun Hong (136797)

“…<p>(A, B) Insulin treatment increased FoxO1 phosphorylation and decreased <i>NPY</i> expression in mouse hypothalamic GT1-7 cells while insulin with AKT inhibitor co-treatment slightly decreased FoxO1 phosphorylation and increased <i>NPY</i> expression. …”

DataSheet_1_2-Deoxy-D-glucose Alleviates Collagen-Induced Arthritis of Rats and Is Accompanied by Metabolic Regulation of the Spleen and Liver.zip by Hongxing Wang (3165948)

“…The changes in the gene-metabolite network of bile secretion in the spleen correlated with a decreased plasma L-acetylcarnitine level in CIA rats and an increase following 2-DG treatment. …”

RER1 expression significantly reduces αSyn levels. by Hyo-Jin Park (4233949)

“…(B) Wild type RER1 expression significantly decreased αSyn levels (mean, 87.8 ±7.1%), but expression of RER1Δ25 resulted in significantly smaller effects on levels of αSyn (mean, 24.3 ±10.6%) (*p<0.05, **p<0.01; F_2,6 = 17.31, p = 0.0032) (n = 5/control, n = 7/RER1, n = 3/ RER1Δ25) in HEK293. …”

Molecules altering the synchrony index, modify Cx36 expression and the size of Cx36 plaques. by Sabine Bavamian (148288)

“…The bars show means + SE ratio of the Cx36 to the <i>β</i>-actin signal, as evaluated by densitometric analysis of 5 independent experiments. *p<0.05 versus DMSO-exposed controls; (<i>B</i>) The volume density (Vv) of Cx36 was increased by some of the drugs that enhanced MIN6 cell synchronization, and decreased by all the drugs decreasing this synchronization. …”

Data_Sheet_1_Spatiotemporal Dynamics of the Carbon Budget and the Response to Grazing in Qinghai Grasslands.docx by Xiaotao Huang (9019376)

“…The NEE of Qinghai grasslands fluctuated from 1979 to 2018, with an average value of −5.16 gC/m². After 2,000, GPP increased, and NEE decreased in a fluctuating manner. …”