Positive feedback on osteoclast formation is critical for obtaining oscillations with increasing amplitude. by Timur Akchurin (377722)

“…C) Simultaneously increasing the value of parameter <i>k</i>₆ and decreasing the value of parameter <i>k</i>₅ allows simulation of experimental observation that the first peak is generally lower in experiments where osteoclasts oscillate with increasing amplitude compared to experiments without oscillations or with damped oscillations of osteoclasts. …”

siRNA-mediated knockdown of selected IGCs impairs GSC viability. by Julia Pollak (234075)

“…CellTiter-Glo viability assay 72 hours following siRNA-mediated knockdown of IGCs. GSC viability decreased in response to increasing amounts of siRNA (2, 5, and 20 pmol). …”

Polarity-Induced Reactive Wetting: Spreading and Retracting Sessile Water Drops by William S. Y. Wong (2795890)

“…Drops contacting the transition spread before retracting, occurring over the time scale of a few seconds. This phenomenon contradicts current understanding, exhibiting a uniquely (1) decreasing advancing contact angle and (2) increasing receding contact angle. …”

Image_1_Risk of CVD Following Radiotherapy for Head and Neck Cancer: An Updated Systematic Review and Meta-Analysis.jpg by Ping-Yi Lin (561526)

“…We found that neck RT was a significant risk factor for CVD (HR 3.97, 95% CI: 2.89-5.45). …”

Data_Sheet_2_Influence of Phytoplankton Advection on the Productivity Along the Atlantic Water Inflow to the Arctic Ocean.pdf by Maria Vernet (5467037)

“…In situ productivity further decreases north of Svalbard Archipelago, at the entrance to the Arctic Ocean. …”

Dipolar Second-Order Nonlinear Optical Chromophores Containing Ferrocene, Octamethylferrocene, and Ruthenocene Donors and Strong π-Acceptors: Crystal Structures and Comparison of π... by Tiffany L. Kinnibrugh (1939771)

“…DFT geometries are in excellent agreement with those determined crystallographically; while the π-donor strengths of the three metallocenyl groups are insufficiently different to result in detectable differences in the crystallographic bond-length alternations, the DFT geometries, as well as DFT calculations of partial charges for atoms, suggest that π-donor strength decreases in the order Fc′′ ≫ Fc > Rc. NMR, IR, and electrochemical evidence also suggests that octamethylferrocenyl is the stronger π-donor, exhibiting similar π-donor strength to a <i>p</i>-(dialkylamino)phenyl group, while ferrocenyl and ruthenocenyl show very similar π-donor strengths to one another in chromophores of this type.…”

Image_3_Xanthine Oxidoreductase Is Involved in Chondrocyte Mineralization and Expressed in Osteoarthritic Damaged Cartilage.JPEG by Sonia Nasi (383541)

“…We showed both in murine primary chondrocyte and chondrogenic ATDC5 cells, that mineralization was inhibited by two different XOR inhibitors, febuxostat and allopurinol. …”

Table_6_RNA 2’-O-Methyltransferase Fibrillarin Facilitates Virus Entry Into Macrophages Through Inhibiting Type I Interferon Response.xlsx by Panpan Li (484033)

“…Once FBL is down-regulated, the decreased Nm modifications of RNA in macrophages may act as “non-self” RNA and be recognized by RNA sensor interferon induced with helicase C domain 1 (MDA5), leading to innate immune activation by inducing the expression of IFN-I and ISGs. …”

Table_1_Predictive model of recurrent ischemic stroke: model development from real-world data.docx by Marwa Elsaeed Elhefnawy (15373273)

“…A time-to-recurrent IS model was developed using NONMEM version 7.5. …”

SEAwise Report on effects of environmental and ecological factors on stock productivity for online tool by Marie Savina-Rolland (12772751)

“…</p><p dir="ltr">Overall, stock productivity tended to decline under climate change: Stock projections under climate change scenarios show decreased biomasses and catch (when compared to a no climate change scenario) for 10 stocks, increased biomasses and catch for 5 stocks, and no or unclear signals for 4 stocks.…”

Image_2_Thermoresponsive Copolymer Nanovectors Improve the Bioavailability of Retrograde Inhibitors in the Treatment of Leishmania Infections.tif by Evan Craig (4025492)

“…It is, therefore, imperative that more effective drug formulations with decreased toxicity profiles are developed. Previous studies had shown that 2-(((5-Methyl-2-thienyl)methylene)amino)-N-phenylbenzamide (also called Retro-2) has efficacy against Leishmania infections. …”

Image_2_Modulation of Motor Cortex Activity After Intrathecal Baclofen Delivery in Chronic Thoracic Spinal Cord Injury.TIFF by Ivana Štětkářová (12540235)

“…</p>Methods<p>Ten subjects (eight males, 20–69 years) with thoracic SCI presenting no voluntary movements of lower limbs (except one) were enrolled in the fMRI study. fMRI at 1.5T with a finger tapping paradigm and mental movement simulating foot flexion on the dominant side were performed before, 3 months, and 1 year after start of cITBa. fMRI data processing was carried out using FMRI Expert Analysis Tool (FEAT), part of FSL. …”

DataSheet3_Neuroprotective effects of Neurotrophin-3 in MPTP-induced zebrafish Parkinson’s disease model.PDF by Noor Azzizah Omar (16880058)

“…<p>Introduction: Neurotrophin-3 (NT3) is a neuroprotective growth factor that induces the development, maintenance and survival of neurons. …”

Table_2_Assessment of Functional and Pasting Properties of Fresh Orange Maize Hybrids and Open-Pollinated Varieties as Influenced by Genotype, Harvesting Time, and Growing Location... by Emmanuel Oladeji Alamu (11751353)

“…Additionally, the water absorption capacity increased between 20 and 27 DAP for the maize hybrids, with a decreasing trend between 27 and 34 DAP. However, genotypes 2, from the orange maize hybrid, and 5, amongst the OPV, were outstanding with the highest peak viscosities, indicating good final product quality. …”

Table_1_Characteristic of Perineural Invasion in Hilar Cholangiocarcinoma Based on Whole-Mount Histologic Large Sections of Liver.docx by Si-Yuan Wang (6307619)

“…Extrahepatic and intrahepatic PNI were identified in 20 (100%) patients and 1 (5.0%) patient, respectively. Vessel density decreased in most invaded nerves presented by CD-34, which correlated with 100% of poorly differentiated and 83% of moderately differentiated tumors (P<0.008).…”

Image_1_Modulation of Motor Cortex Activity After Intrathecal Baclofen Delivery in Chronic Thoracic Spinal Cord Injury.TIFF by Ivana Štětkářová (12540235)

“…</p>Methods<p>Ten subjects (eight males, 20–69 years) with thoracic SCI presenting no voluntary movements of lower limbs (except one) were enrolled in the fMRI study. fMRI at 1.5T with a finger tapping paradigm and mental movement simulating foot flexion on the dominant side were performed before, 3 months, and 1 year after start of cITBa. fMRI data processing was carried out using FMRI Expert Analysis Tool (FEAT), part of FSL. …”

Intestinal <i>H. hepaticus</i> infection triggers systemic elevations in pro-inflammatory cytokines. by Theofilos Poutahidis (288280)

“…<p><b>A</b>) Serum levels of pro-inflammatory cytokines were increased in <i>Apc</i>^<i>Min/+</i> mice after <i>H</i>. …”

Image_10_Identification, Characterization, and Expression Profile Analysis of the mTERF Gene Family and Its Role in the Response to Abiotic Stress in Barley (Hordeum vulgare L.).JP... by Tingting Li (10553)

“…In this study, we identified 60 mTERFs in the barley genome (HvmTERFs) through a comprehensive search against the most updated barley reference genome, Morex V2. …”

Supplementary Material for: MDM2 is essential to maintain the homeostasis of epithelial cells by targeting p53 by Wang S. (3116754)

“…A mechanistic study showed that following the decreased expression of Mdm2 in lung epithelial cells and A549 cell line, p53 was overactivated, and the expression of its downstream genes p21, Puma, and Noxa was elevated, which resulted in apoptosis. …”

DataSheet_1_Modulating Neuro-Immune-Induced Macrophage Polarization With Topiramate Attenuates Experimental Abdominal Aortic Aneurysm.zip by Xing Chen (140292)

“…Topiramate, which is an agonist of the GABA_A receptor, makes contributions to neuronal disease and is partially involved in immune regulation, may be effective upon abdominal aortic aneurysm progression. …”