Table 1_Mechanism of action of Butein in cutaneous squamous cell carcinoma through regulation of the TWEAK-FN14 signaling pathway.docx by Qinyi Dong (22824800)

“…</p>Results<p>Molecular docking predicted that Butein exhibits strong binding affinity with TWEAK, FN14, cIAP1, and TRAF1/2 proteins, with binding energies ranging from −5.8 to −6.9 kcal/mol.In vitro experiments demonstrated that Butein inhibited the proliferation and migration of human cSCC cell line A431 with an IC₅₀ of 43 μM and induced dose-dependent apoptosis. …”

Relative membrane levels of endogenous endoglin in HMEC-1 cells upon transient or stable mutant protein expression. by Tassilo Förg (606727)

“…Cells expressing the variant endoglin^ΔC (DC, without cytoplasmic domain) showed a 1.5 times higher ectopic expression than endoglin^wt.…”

Table 1_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Furthermore, the expression of SA and JA response-related genes (NbPR5 and NbPR12) was up-regulated in NbSOS1-13-silenced plants.…”

Data from: Innovative Methodology for Antimicrobial Susceptibility Determination in Mycoplasma Biofilms by Bryan Tegner Jacobson (20554884)

“…For mature biofilms that were cultured for 4- 5 days before antibiotic exposure, results also were variable, with some strains showing an increased resistance with certain antibiotics and a decreased resistance with others. …”

Table4_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Table8_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx by Ye Yang (297214)

“…RT-qPCR revealed that the CKO mice presented a significantly less transcription of Sp5, an important element of the Wnt signaling pathway.…”

Celastrol increases the protein level of HIF-1α. by Xiaoxi Han (407707)

“…<p>1a. Celastrol dose-dependently enhanced HIF-1α expression under hypoxia. …”

Additional file 2 of Endotoxemia and circulating bacteriome in severe COVID-19 patients by Phatadon Sirivongrangson (9742671)

“…Shannon diversity index (A) and Chao1 richness (B) representing alpha diversity of bacterial community profiles in COVID-19 patients on day 1, 3, and 7. …”

DataSheet_1_Transcriptional changes in the gilthead seabream (Sparus aurata) skin in response to ultraviolet B radiation exposure.docx by Ricardo N. Alves (8839895)

“…S. aurata juveniles were exposed for 43 days to two experimental groups: 1) UVB (daily dose, 6 kJ m^-2; representing levels between 5 and 7 m depth); 2) Unirradiated treatment, used as a control. …”

Table_1_The changes and its significance of peripheral blood NK cells in patients with tuberculous meningitis.DOCX by Jie Mi (152887)

“…The proportion of TBM patients (48.7%) with a lower absolute count of NK cells than the normal reference value was significantly higher than that in NC (5.2%) and LTBI groups (4.0%) (p < 0.05), and slightly higher than that in NSTB group (36.0%) (p > 0.05). …”

Image_1_Microwave ablation with hydrodissection used for the treatment of vascular malformations: effectiveness and safety study.jpeg by Lu Wang (45927)

“…</p>Results<p>Among the 39 VMs, the maximum volume is 128.58ml, while the minimum volume is 0.99ml. After a mean follow-up of 13.06 ± 4.83 months, the mean numerical rating scale (NRS) score decreased from 5.13 ± 1.65 to 0.53 ± 0.83 (P<0.0001). …”

Data_Sheet_1_Tle4z1 Facilitate the Male Sexual Differentiation of Chicken Embryos.doc by Chen Chen (6544)

“…Background<p>Sex differentiation is a complex and precisely regulated process by multiple genes in chicken. …”

Tropical fishes can benefit more from novel than familiar species interactions at their cold-range edges by Angus Mitchell (8391018)

“…</p><p dir="ltr">3. All five tropical fish species showed increased anti-predator behaviours and decreased bite rate at their novel temperate range compared to their native tropical and subtropical ranges. …”

DataSheet_1_Immunoregulatory effects of RGMb in gut inflammation.docx by Magdiel Pérez-Cruz (6422627)

“…Anti-RGMb mAb (9D1) treatment decreased IFN-γ and significantly increased IL-5 and IL-10 in the gut of the treated mice compared to the isotype control treated mice.…”

Downregulation of Protein Kinase CK2 Activity Facilitates Tumor Necrosis Factor-α-Mediated Chondrocyte Death through Apoptosis and Autophagy by Sung Won Lee (222509)

“…It should be clarified in the future if autophagy observed is a consequence versus a cause of the degeneration <em>in vivo.…”

Image_1_Cell origin and genome profile difference of penoscrotum invasive extramammary Paget disease compared with its in situ counterpart.jpeg by Yamin Rao (13166352)

“…In our cohort, invasive pEMPD presented increased expression of androgen receptor and decreased MUC5CA expression, and these two changes might bring to the shift of invasive phenotype. …”

DataSheet1_Albuca Bracteata Polysaccharides Attenuate AOM/DSS Induced Colon Tumorigenesis via Regulating Oxidative Stress, Inflammation and Gut Microbiota in Mice.docx by Ziyan Qin (4058464)

“…In this study, we investigate the properties of polysaccharides of A. bracteate, named ABP. The average molecular weight of ABP was 18.3 kDa and ABP consisted of glucose, mannose, galactose, xylose, galacturonic acid, glucuronic acid at a molar ratio of 37.8:8:2.5:1.7:1:1. …”

Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx by Fei Yan (128878)

“…The median OS was not reached (95% CI: 13.27-NR), with a 1-year OS rate of 73.5% (95% CI: 60.4–89.3%). …”

Table_4_Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis.xlsx by Wan-Chun Li (450324)

“…Loss of HK2 in HNSCC cells resulted in reduced cell (in vitro) and tumor (in vivo) growth, as well as decreased epithelial-mesenchymal transition–mediated cell movement; in contrast, HK2-deficient HNSCC cells exhibited greater sensitivity to chemotherapeutic drugs cisplatin and 5-fluorouracil but are more resistant to photodynamic therapy, indicating that HK2 expression could selectively define treatment sensitivity in HNSCC cells. …”

Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing by Saartje Bloemen (820484)

“…In conclusion, bleeding in patients taking VKAs is associated with a decreased whole blood ETP and peak as well as with an increased HAS-BLED score.…”