Defective expression of <i>Foxa2</i> and <i>Gsc</i> at the late streak stage of ethanol-treated <i>Cdon^−/−</i> embryos. by Mingi Hong (129953)

“…<i>Cdon</i> expression was also monitored via ß-galactosidase (ß-gal) activity derived from a <i>LacZ</i> reporter knocked into the <i>Cdon</i> locus in mutant E7.5 embryos (O) at the early bud stage; a wild-type embryo stained for ß-gal activity is shown as a negative control (N). …”

Proportional distribution of mutated and ambiguous mutated amino acids at HIVDR sites. by Du-Ping Zheng (40489)

“…The scores were summed by 1 for a pure amino acid mutation and 0.5 for an ambiguous amino acid mutation, and then converted to percentages against the total number of wild-type amino acids at the site. …”

Different simulations of disruption scenarios for 1 year. by Brinkley Raynor (10844527)

“…Panels A-C depict different vaccination scenarios with normal levels of surveillance and control measures leading to an average survival time (ST) of rabid dogs to be 2.5 days. …”

Model Predictions. by Carmen Pin (113170)

“…C) The time for the propagation of a mutation to the stem cell compartment is shorter when the mutation decreases the duration of the division cycle. …”

Early Fumagillin Treatment is Associated with Growth in Monocrotaline-Injured Rats. by Daniel J. Kass (173086)

“…At weeks 1–4, all MCT-injured animals gained weight at a similar rate (A). Panel (B) represents the data shown in panel (A) at week 5. …”

One-parameter bifurcation diagrams for the DA neuron and the HH neuron. by Andrey Dovzhenok (311885)

“…Parameters are from C), except that the K⁺ current half-activation is decreased by 5 mV (<i>v</i>_nh = −58 mV). …”

Suppression of NF-κB signaling in <i>Iqgap2</i>^<i>-/-</i> colons. by Amr M. Ghaleb (668342)

“…<p><b>A.</b> IHC shows decreased baseline levels of p65 subunit of NF-κB in <i>Iqgap2</i>^<i>-/-</i> colon compared to WT (panels a, d). …”

Effects of lipid raft perturbation on Dectin-1 dynamics during phagocytosis. by Valeria de Turris (825676)

“…The resulting effect of these events was a severely decreased phagocytosis. See also Supplementary <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0142531#pone.0142531.s002" target="_blank">S2</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0142531#pone.0142531.s003" target="_blank">S3</a> Movies.…”

Microscopy Image Dataset for Deep Learning-Based Quantitative Assessment of Pulmonary Vascular Changes by Aleksandr Sinitca (14513951)

Morpholino knockdown of <i>hjv</i> results in notochord and somite abnormalities. by Yann Gibert (232725)

“…Somites (arrows) in uninjected (<b>H</b>) and control morpholino-injected embryos (<b>I</b>) appeared V-shaped, while somites appeared U-shaped with decreased anterior-posterior dimension (distance between each pair of arrows) in <i>hjv</i> morphants (<b>J</b>). …”

PCR and WB of KLF8 after shRNA knockdown in U87-MG. by Oliver Schnell (187202)

“…(B) Subsequent Western Blot analysis of the nuclear fraction of KLF8-kd U87-MG cells on day 4 after seeding revealed that KLF8 protein was still detectable in all transfected U87-MG cells but only to a small extent in the KLF8-knockdown cells indicating that shRNA-knockdown was successful in these transfected cells in concordance with the qPCR results (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030429#pone-0030429-g005" target="_blank">Figure 5A</a>).…”

Retreatment status in the 2+L cohort. by Shinsuke Iida (385074)

“…Retreatment with lenalidomide-, daratumumab-, and isatuximab-based therapy occurred in 44.1%, 35.2%, and 5.6% of patients, respectively.</p><p>Conclusion</p><p>The high use of lenalidomide and DRd in 1L, and high rates of retreatment with lenalidomide and anti-CD38 mAbs in 2L+ indicate a substantial need for new treatment modalities that can be used in 2L+ patients who previously received lenalidomide with/without an anti-CD38 mAb therapy.…”

Proline utilization is influenced by carbon source but not by NCR. by Fitz Gerald S. Silao (138169)

“…Respiratory growth predominates as glucose level decreases. WT cells were diluted to OD₆₀₀ of 0.5 in pre-warmed synthetic proline media containing 10 mM proline (YNB+Pro+BCP) and the indicated levels of glucose with the initial pH adjusted to 6.0. …”

Attrition of the study sample. by Shinsuke Iida (385074)

“…Retreatment with lenalidomide-, daratumumab-, and isatuximab-based therapy occurred in 44.1%, 35.2%, and 5.6% of patients, respectively.</p><p>Conclusion</p><p>The high use of lenalidomide and DRd in 1L, and high rates of retreatment with lenalidomide and anti-CD38 mAbs in 2L+ indicate a substantial need for new treatment modalities that can be used in 2L+ patients who previously received lenalidomide with/without an anti-CD38 mAb therapy.…”

Vocalization subsystem responses (Croake et al., 2018) by Daniel J. Croake (4873486)

“…Acoustic formant measures indicated that the spacing between the upper formants decreased (F3–F5), whereas the spacing between F1 and F2 increased. …”

Frequency distribution of depths of coverage (DP) and allele balances (AB). by Eileen Marie Hanna (9693992)

“…The depth of coverage distribution is shown to have its mode around 40x after which the frequency keeps decreasing. The allele balances of the heterozygous variants vary around a maximum frequency of 0.5, while the balances of the homozygous variants are at the single line at value 1.…”

Co-localisation of Runx1t1 and OX42 in the postnatal rat brain by double immunofluorescent staining. by Nimmi Baby (524594)

“…<p>Confocal images showing the expression of Runx1t1 (B,E,H,K,N,Q; red) in OX42-positive (A,D,G,J,M,P; green) microglia (C,F,I,L,O,R; yellow) from the corpus callosum of 1, 3, 5,7, 14& 21 days rat brains, respectively. …”

Data_Sheet_1_In vitro and in vivo Virulence Potential of the Emergent Species of the Acinetobacter baumannii (Ab) Group.xlsx by Clara Cosgaya (7536140)

“…In this study 76 isolates of 5 species within the Ab group (A. baumannii n = 16, A. lactucae n = 12, A. nosocomialis n = 16, A. pittii n = 20, and A. seifertii n = 12), were compared in terms of antimicrobial susceptibility, carriage of intrinsic resistance genes, biofilm formation, and the ability to kill Caenorhabditis elegans in an infection assay. …”

Table_1_In vitro and in vivo Virulence Potential of the Emergent Species of the Acinetobacter baumannii (Ab) Group.pdf by Clara Cosgaya (7536140)

“…In this study 76 isolates of 5 species within the Ab group (A. baumannii n = 16, A. lactucae n = 12, A. nosocomialis n = 16, A. pittii n = 20, and A. seifertii n = 12), were compared in terms of antimicrobial susceptibility, carriage of intrinsic resistance genes, biofilm formation, and the ability to kill Caenorhabditis elegans in an infection assay. …”

Image_1_In vitro and in vivo Virulence Potential of the Emergent Species of the Acinetobacter baumannii (Ab) Group.tif by Clara Cosgaya (7536140)

“…In this study 76 isolates of 5 species within the Ab group (A. baumannii n = 16, A. lactucae n = 12, A. nosocomialis n = 16, A. pittii n = 20, and A. seifertii n = 12), were compared in terms of antimicrobial susceptibility, carriage of intrinsic resistance genes, biofilm formation, and the ability to kill Caenorhabditis elegans in an infection assay. …”