SREBP-1 expression increases insulin signaling in primary hepatocytes. by Victoria Jideonwo (5172071)

“…<p><b>(A)</b> Mouse primary hepatocytes were cultured in DMEM containing 5 mM glucose, 10% FBS and 100 IU/ml penicillin/100 μg/ml streptomycin, 100 nM dexamethasone. …”

YK-4-279 inhibits ETV1 target gene expression in-vivo. by Said Rahim (222786)

“…Experiments were performed in triplicates with 5 mice analyzed per group. YK-4-279 treatment resulted in decreased gene expression of MMP7, GLYATL2 and FKBP10 without significant reduction in ETV1 levels. *; p<0.05, n.s.; not-significant, unpaired student's t-test. b) ETV1 target gene expression levels in late treatment study high dose group. *; p<0.05, n.s.; not-significant, unpaired student's t-test.…”

Patients with atrial fibrillation and permanent pacemaker: Temporal changes in patient characteristics and pharmacotherapy by Frederik Dalgaard (5029952)

“…Thus, the proportional amount of NVAF patients with a PPM decreased from 1.3% to 1.1% (p = 0.015). …”

Mtb infection induced alternate polyadenylation in THP-1 macrophages. by Haroon Kalam (3813094)

“…<p>(A) Number of transcripts in the human genome known to have 1, 2 to 5, 6 to 10 or more than 10 reported 3’UTRs is shown here as obtained from NCBI database. …”

Changes in gene transcript abundance following TDV vaccination. by Fiona R. Strouts (2805394)

“…FDR<0.05; fold-change≥1.3 solid areas, fold-change≥1.5 dashed areas. Red bars indicate increased abundance; blue bars indicate decreased abundance. …”

Image_2_Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children.JPEG by Juan Chen (61123)

“…Meanwhile, increases of 20, 120, 245, and 395 mg/L from 5 mg/L in CRP levels were associated with increases in voriconazole dose requirements by 7.15, 14.23, 17.35, and 19.43%, respectively, in the PM group; with decreases in voriconazole dose requirements by 3.71, 7.38, 8.97, and 10.03%, respectively, in the NM group; and with decreases by 4, 9.10, 11.05, and 12.35%, respectively, in the IM group. …”

DataSheet4_Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.xlsx by Lili Lin (451927)

“…Finally, pharmacodynamic investigations indicated that QF reduced airway inflammation caused by excessive autophagy by decreasing lung levels of RSV F and G proteins, Beclin-1, Atg5, and LC3B II, IL-1 and TNF-α (p < 0.05).…”

DataSheet2_Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.xlsx by Lili Lin (451927)

“…Finally, pharmacodynamic investigations indicated that QF reduced airway inflammation caused by excessive autophagy by decreasing lung levels of RSV F and G proteins, Beclin-1, Atg5, and LC3B II, IL-1 and TNF-α (p < 0.05).…”

DataSheet1_The Multiple Metamorphism of Mafic Granulites From the East Hebei Terrane, North China Craton: Insights Into the Transition of Tectonic Regimes.DOCX by Ting Liu (45625)

“…The first-episode recovered from JD15120 and YC8-43 is represented by peak assemblage of medium-grained clinopyroxene, orthopyroxene, amphibole, plagioclase, and ilmenite, which yields ultrahigh temperature (UHT) conditions of 940–960°C at 7.5–8.5 kbar and 950–990°C at 8 kbar, respectively, constrained by contours of the maximum anorthite (X_An) in plagioclase cores. …”

DataSheet3_Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.xlsx by Lili Lin (451927)

“…Finally, pharmacodynamic investigations indicated that QF reduced airway inflammation caused by excessive autophagy by decreasing lung levels of RSV F and G proteins, Beclin-1, Atg5, and LC3B II, IL-1 and TNF-α (p < 0.05).…”

Table_1_Association of egg intake with risks of cardiometabolic factors among adults in China.docx by Yingying Jiao (10433030)

“…After adjusting for demographic characteristics, lifestyle, energy and BMI, using the lowest quintile (Q1) as a reference, the risk of central obesity, elevated TG, decreased HDL-C, and elevated plasma glucose in the highest quintile (Q5) were reduced by 15% (HR = 0.85, 95% CI = 0.73–0.98, P = 0.16), 33% (HR = 0.67, 95% CI = 0.57–0.78), 25% (HR = 0.75, 95% CI = 0.63 0.90, p = 0.05), and 28% (HR = 0.72, 95% CI = 0.63–0.83, p < 0.05), respectively. …”

DataSheet6_Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.pdf by Lili Lin (451927)

“…Finally, pharmacodynamic investigations indicated that QF reduced airway inflammation caused by excessive autophagy by decreasing lung levels of RSV F and G proteins, Beclin-1, Atg5, and LC3B II, IL-1 and TNF-α (p < 0.05).…”

DataSheet1_Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation.doc by Lili Lin (451927)

“…Finally, pharmacodynamic investigations indicated that QF reduced airway inflammation caused by excessive autophagy by decreasing lung levels of RSV F and G proteins, Beclin-1, Atg5, and LC3B II, IL-1 and TNF-α (p < 0.05).…”

Image_1_Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children.JPEG by Juan Chen (61123)

“…Meanwhile, increases of 20, 120, 245, and 395 mg/L from 5 mg/L in CRP levels were associated with increases in voriconazole dose requirements by 7.15, 14.23, 17.35, and 19.43%, respectively, in the PM group; with decreases in voriconazole dose requirements by 3.71, 7.38, 8.97, and 10.03%, respectively, in the NM group; and with decreases by 4, 9.10, 11.05, and 12.35%, respectively, in the IM group. …”

The number of English- and non-English-language studies testing the effectiveness of conservation interventions for each amphibian, bird, and mammal species. by Tatsuya Amano (544039)

“…Note that 2 mammal species with 82 and 63 English-language studies are not shown as outliers (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001296#pbio.3001296.s013" target="_blank">S5 Data</a>). …”

Fatty Acid Solubilizer from the Oral Disk of the Blowfly by Yuko Ishida (104789)

“…The binding affinity of PregOBP56a decreased at pH 5. We propose that PregOBP56a is a protein that solubilizes fatty acids during feeding and subsequently helps to deliver the fatty acids to the midgut where it may help in the process of reproduction. …”

Changes in relative abundance of genera in both therapeutic groups. by Flavia Furlaneto (20161022)

“…Negative values refer to reduction in abundance after treatment (Mann-Whitney test, a, p = 0.049; b, p = 0.001; c, p = 0.006). For instance, <i>Catonella</i> had a median increase of 35.5% in the probiotic group compared to a median reduction of 52% in the placebo. …”

CLUES captures bivalent chromatin status, core regulation genes circuitry and novel self-renewal and pluripotency regulators of mouse ES cells by integrating prioritized broad E-si... by Chao Wu (199897)

“…Y-axes, RPKM of Nanog, Oct4, H3K4me3, and H3K27me3 ChIP-Seq datasets and RNA-Seq datasets. c. A heat-map of broad H3K4me3 E-signals associated with broad H3K27me3 E-signals, top-ranked Nanog (top 5%) and top-ranked Oct4 (top 5%) broad E-signals. …”

Table1_Synthesis of green zinc‐oxide nanoparticles and its dose‐dependent beneficial effect on spermatozoa during preservation: sperm functional integrity, fertility and antimicrob... by Meiaishan Eliezer Lyngdoh (18013783)

“…This study demonstrates the beneficial effect of zinc oxide nanoparticles (ZnO-NPs) as an additive to semen extenders to improve semen quality, fertility, and antibacterial activity during liquid preservation in a boar model.</p><p>Methods: Initially, to find out the safe concentration of ZnO-NPs in sperm cells, a wide range of ZnO-NP concentrations (0, 5, 10, 50, 100, 500, and 1,000 μM) were co-incubated with sperm at 37°C for a cytotoxic study. …”

Image1_Synthesis of green zinc‐oxide nanoparticles and its dose‐dependent beneficial effect on spermatozoa during preservation: sperm functional integrity, fertility and antimicrob... by Meiaishan Eliezer Lyngdoh (18013783)

“…This study demonstrates the beneficial effect of zinc oxide nanoparticles (ZnO-NPs) as an additive to semen extenders to improve semen quality, fertility, and antibacterial activity during liquid preservation in a boar model.</p><p>Methods: Initially, to find out the safe concentration of ZnO-NPs in sperm cells, a wide range of ZnO-NP concentrations (0, 5, 10, 50, 100, 500, and 1,000 μM) were co-incubated with sperm at 37°C for a cytotoxic study. …”