Upregulation of HLA Expression in Primary Uveal Melanoma by Infiltrating Leukocytes by T. Huibertus van Essen (3233880)

“…Implantation of fresh human tumor samples into SCID mice led to a loss of infiltrating leukocytes, and to a decreased expression of HLA class I and II genes, and their regulators.…”

Data_Sheet_1_Association of dietary total antioxidant capacity and its distribution across three meals with all-cause, cancer, and non-cancer mortality among cancer survivors: the... by Peng Wang (34436)

“…Among cancer survivors, compared with participants in the lowest quartile of total DAC from three meals, those in the highest quartile had a 24% decreased risk of noncancer mortality (aHR = 0.76, 95% confidence interval [CI]: 0.60–0.92), but not of all-cause and cancer mortality (each p trend >0.1). …”

Table 8_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.xlsx by Haibi Zhao (10869861)

“…Thirty-six male Hu sheep (2 months old) with similar weight [(10 ± 0.5) kg] were randomly divided into four groups of nine sheep each, and were divided into groups A (FNDF/starch = 0), B (FNDF/starch = 0.23), C (FNDF/starch = 0.56) and D (FNDF/starch = 1.10) with different FNDF/starch of pelleted rations, respectively. …”

Image 2_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.tif by Haibi Zhao (10869861)

“…Thirty-six male Hu sheep (2 months old) with similar weight [(10 ± 0.5) kg] were randomly divided into four groups of nine sheep each, and were divided into groups A (FNDF/starch = 0), B (FNDF/starch = 0.23), C (FNDF/starch = 0.56) and D (FNDF/starch = 1.10) with different FNDF/starch of pelleted rations, respectively. …”

Eyes shut homolog is important for the maintenance of photoreceptor morphology and visual function in zebrafish by Muriël Messchaert (5565926)

“…The transcript is predicted to encode a 2,905-aa protein that contains 39 EGF-like domains and five laminin A G-like domains, which overall shows 33% identity with human EYS. …”

Image_1_Integrating Serum Metabolome and Gut Microbiome to Evaluate the Benefits of Lauric Acid on Lipopolysaccharide- Challenged Broilers.tif by Yanping Wu (626519)

“…LA enhanced immune functions and inhibited inflammatory responses by upregulating the concentrations of immunoglobulins (IgA, IgM, and IgY), decreasing IL-6 and increasing IL-4 and IL-10. …”

Drivers of Tree Growth, Mortality and Harvest Preferences in Species-Rich Plantations for Smallholders and Communities in the Tropics by Huong Nguyen (43776)

“…While tree density of stands at age 10+ years (more than 1000 trees/ha with diameter > 5cm) did not have an impact on growth, growth rates were decreasing in stands with a high basal area. …”

Table 4_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.xlsx by Haibi Zhao (10869861)

“…Thirty-six male Hu sheep (2 months old) with similar weight [(10 ± 0.5) kg] were randomly divided into four groups of nine sheep each, and were divided into groups A (FNDF/starch = 0), B (FNDF/starch = 0.23), C (FNDF/starch = 0.56) and D (FNDF/starch = 1.10) with different FNDF/starch of pelleted rations, respectively. …”

Conophylline inhibits high fat diet-induced non-alcoholic fatty liver disease in mice by Tomohiko Ohashi (4096861)

“…However, little is known about the CnP mediated inhibition of hepatic steatosis in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD) mouse models. CnP (0.5 and 1 μg/g/body weight) was co-administered along with a high-fat diet to male BALB/c mice. …”

Table 7_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.xlsx by Haibi Zhao (10869861)

“…Thirty-six male Hu sheep (2 months old) with similar weight [(10 ± 0.5) kg] were randomly divided into four groups of nine sheep each, and were divided into groups A (FNDF/starch = 0), B (FNDF/starch = 0.23), C (FNDF/starch = 0.56) and D (FNDF/starch = 1.10) with different FNDF/starch of pelleted rations, respectively. …”

Differences in Meiotic Recombination Rates in Childhood Acute Lymphoblastic Leukemia at an MHC Class II Hotspot Close to Disease Associated Haplotypes by Pamela Thompson (449563)

“…Of four haplotype blocks identified, predicted haplotypes in Block 1 (centromeric of <i>DNA3</i>) differed significantly between BCP-ALL and controls (P = 0.002) and in Block 4 (including <i>HLA-DPB1</i>) between T-ALL and controls (P = 0.049). Of specific common (>5%) haplotypes in Block 1, two were less frequent in BCP-ALL, and in Block 4 a single haplotype was more frequent in T-ALL, compared to controls. …”

Improved Muscle Function in Duchenne Muscular Dystrophy through L-Arginine and Metformin: An Investigator-Initiated, Open-Label, Single-Center, Proof-Of-Concept-Study by Patricia Hafner (479961)

“…Five ambulatory, genetically confirmed Duchenne muscular dystrophy patients aged between 7–10 years were treated with L-arginine (3 x 2.5 g/d) and metformin (2 x 250 mg/d) for 16 weeks. …”

The effects of acute administration of dexamfetamine on spontaneous swimming and on startle response. by Stefan Spulber (148803)

“…In larvae exposed to 1 mg/L PFOS, the amplitude of the startle response is not altered (presumably accounted for by more than one bout; see also D and E), but the duration of hyperactivity following the vibrational stimulation is shortened by both 1 and 10 µM dexamfetamine (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094227#pone.0094227.s005" target="_blank">Figure S5</a>). …”

Determination of gene expression signature for high microglia/macrophage infiltrate and association with cell-specific gene signatures and molecular subtypes. by Jane R. Engler (140558)

“…(<b>B</b>) Q-Q plot of genes differentially expressed in high microglia/macrophage tumors (n = 9) and low microglia/macrophage tumors (n = 9), as denoted in (A). (<b>C</b>) Unsupervised hierarchical clustering of adult GBMs (TCGA, n = 573), based on the six differentially expressed genes between high and low microglia/macrophage tumors as denoted in (A) and shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043339#pone-0043339-t002" target="_blank">Table 2</a>, identified four distinct clusters (red, increased expression and green, decreased expression). …”

Improved HLA-class I restricted avidity of CD8αß expressing HA-2-TCR td CD4⁺ T-cells results in improved proliferation. by Marleen M. van Loenen (416496)

“…Histograms depict PKH dilution measured 5 days after stimulation, and a representative example of 2 independent experiments is depicted.…”

H3K27me3 ChIP-seq. by Dana Lau-Corona (8861900)

“…Also see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008796#pgen.1008796.s014" target="_blank">S6A Table</a>. …”

Image 1_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.tif by Haibi Zhao (10869861)

“…Thirty-six male Hu sheep (2 months old) with similar weight [(10 ± 0.5) kg] were randomly divided into four groups of nine sheep each, and were divided into groups A (FNDF/starch = 0), B (FNDF/starch = 0.23), C (FNDF/starch = 0.56) and D (FNDF/starch = 1.10) with different FNDF/starch of pelleted rations, respectively. …”

Single-driver controllability of brain networks. by Remy Ben Messaoud (20521877)

“…Colors code for different systems. Values are shown for a representative subject. By decreasing <i>r</i> all values become positive and numerically reliable after a critical threshold <i>r</i>*. …”

Alteration in Endometrial Proteins during Early- and Mid-Secretory Phases of the Cycle in Women with Unexplained Infertility by Murli Manohar (423568)

“…The expression of Ras-related protein Rap-1b, Protein disulfide isomerase A3, Apolipoprotein-A1 (Apo-A1), Cofilin-1 and RAN GTP-binding nuclear protein (Ran) were found to be significantly increased, whereas, Tubulin polymerization promoting protein family member 3, Superoxide dismutase [Cu-Zn], Sorcin, and Proteasome subunit alpha type-5 were significantly decreased in mid- secretory phase endometrium of infertile women as compared to early-secretory phase endometrium of infertile women. …”

Data_Sheet_2_Features and Colonization Strategies of Enterococcus faecalis in the Gut of Bombyx mori.pdf by Xiancui Zhang (8349426)

“…In addition, the successful colonization of E. faecalis LX10 led to drastically increased expression of all adhesion genes (znuA, lepB, hssA, adhE, EbpA, and Lap), defense genes (cspp, tagF, and esp), regulation gene (BfmRS), secretion gene (prkC) and immune evasion genes (patA and patB), while the expression of iron acquisition genes (ddpD and metN) was largely unchanged or decreased. …”