FTI-277 treatment reversed burn-induced impaired insulin receptor (IR)-insulin receptor substrate-1 (IRS-1) signaling in skeletal muscle. by Harumasa Nakazawa (684211)

“…Insulin significantly increased p-IRS-1/GAPDH ratio and p-IRS-1/IRS-1 ratio in sham-burned mice and FTI-277-treated burned mice, whereas insulin failed to significantly increase p-IRS-1/GAPDH ratio or p-IRS-1/IRS-1 ratio in vehicle-treated burned mice (F, G). There was a trend of increase in insulin-stimulated p-IRS-1/IRS-1 ratio in vehicle-treated burned mice, but there was no statistical difference (G). n = 5 mice per group for saline-injected mice, n = 6 mice per group for insulin-injected sham-burned mice, n = 8 mice per group for insulin-injected burned mice. …”

Relation between different CTL mechanisms, non-CTL inhibition and HT during infection clearance. by Ashish Goyal (644290)

“…As non-CTL inhibition increases in strength, the number of cells required to be killed by each CTL (<i>n</i>_<i>CTL</i>) to achieve clearance either remains constant or decreases. For a given non-CTL inhibition, an <i>n</i>_<i>R</i> higher than <i>n</i>_<i>CTL</i> will also clear infection with lower HT. …”

Results from the virtual experiment using the diffusion model. by Honghan Li (19332798)

“…(B) Relationship between distance from the geometrically constrained edge <i>r</i>* and probability of generating SFs <i>P</i>_<i>mean</i> for three cases of aspect ratio (<i>AR</i> = 1, 3 and 5). (C,D) Probability distribution function (PDF) of the probability of generating SFs <i>P</i> with a constraint of (C) <i>AR</i> = 1 and (D) <i>AR</i> = 3. …”

Physiological and Molecular Alterations Promoted by <i>Schizotetranychus oryzae</i> Mite Infestation in Rice Leaves by Giseli Buffon (1392436)

Mechanisms mediating risk for HIV acquisition and transmission in menopausal women. by Kerry Murphy (724422)

“…During menopause there is a loss of epithelial barrier integrity (1) and increase in BV associated species including <i>Atopobium</i>, <i>Prevotella</i>, and <i>Gardnerella</i> (2), which influence release of proinflammatory cytokines e.g. …”

Data_Sheet_1_Optimisation of Lactobacillus fermentation conditions and its application in the fermentation of salt-free sauerkraut.PDF by Wenlun Wang (18863641)

“…The total number of bacterial colonies decreased by 37.5%. All other indicators complied with the national standard, providing overall the basis to improve salt-free sauerkraut fermentation.…”

Image_2_Integrating Mortality Risk and the Adaptiveness of Hibernation.pdf by Théo Constant (9109544)

“…Hibernation is considered a seasonal adaptation to prolonged periods of food shortage and cold. …”

Table1_Integratively Genomic Analysis Reveals the Prognostic and Immunological Characteristics of Pyroptosis and Ferroptosis in Pancreatic Cancer for Precision Immunotherapy.XLSX by Ting Yu (156230)

“…A high P-F score was associated with active immune phenotype, decreased genomic alterations, and significantly longer survival. …”

Long-term effects of neonatal malnutrition on microbicide response, production of cytokines, and survival of macrophages infected by Staphylococcus aureus sensitive/resistant to me... by Natália Gomes de Morais (10470273)

“…The plates were incubated in a humid atmosphere at 37 degrees Celsius containing 5% CO2 for 24 hours. …”

Image_1_Physiological and molecular mechanisms of the response of roots of Pinus massoniana Lamb. to low-temperature stress.png by Jingyu Lu (621174)

“…BAM, 4CL, CCoAOMT, PRX5, WRKYs, and hormone synthesis related genes play important roles. …”

IL-6 increases Oct-4 and telomerase expression in KPCs and SKPs. by Qunzhou Zhang (257627)

“…The results are representative of at least five independent experiments using KPCs and the matched SKPs from different patient donors (n = 5).…”

Data Sheet 1_Supply chain integration, strategic choice and corporate growth of agricultural companies: an analysis of dynamic QCA.csv by Xiaonan Fan (5743178)

“…At the strategy level, entrepreneurial orientation is crucial for the corporate growth. (5) There is a substitution relationship between the factors. …”

Effect of dihydroferulic acid obtained from fermented rice bran extract on neuroprotection and behavioral recovery in an ischemic rat model by Sang Hyun LEE (5160065)

“…In vivo dFA administration exerted a neuroprotective effect by reducing the infarct volume and enhancing behavioral function following cerebral ischemia. dFA treatment protected neuronal cells from ischemic injury and increased the transcription levels of anti-oxidant genes (PDI and Nrf2) and neurotrophic factors (BDNF and NGF). dFA treatment decreased the expression of Iba-1 and MFG-E8 genes, which signal neural cell death.…”

Supplemental Figure 1-8 from Dual HDAC and PI3K Inhibitor CUDC-907 Downregulates MYC and Suppresses Growth of MYC-dependent Cancers by Kaiming Sun (15069697)

“…CUDC-907 does not induce significant body weight loss or obvious toxicity in human DLBCL cell line-derived xenograft models or Eμ-Myc transgenic tumor mouse syngeneic models of B-cell lymphoma; Supplemental Figure S5. CUDC-907 decreases MYC protein levels in cell line-derived Burkitt lymphoma xenograft tumors; Supplemental Figure S6. …”

Table6_Integratively Genomic Analysis Reveals the Prognostic and Immunological Characteristics of Pyroptosis and Ferroptosis in Pancreatic Cancer for Precision Immunotherapy.XLSX by Ting Yu (156230)

“…A high P-F score was associated with active immune phenotype, decreased genomic alterations, and significantly longer survival. …”

STC in the bladder leads to increased expression of YAP/WWTR1 target genes. by Karen J. Aitken (16679497)

“…<p><b>A:</b> Pan-<i>BDNF</i> at 1 and 7 weeks augmented significantly with STC, but not incision at 1week. …”

Untitled Ite<b>Elucidating the Gut Microbiota-Driven Crosstalk: Mechanistic Interplay of </b><b>Lobetyolin</b><b> in Coordinating Cholesterol Homeostasis and Anti-Inflammatory Path... by Guofeng Duan (14590910)

“…Lobetyolin enhances the expression of ABCA1, ABCG5, ABCG8, and LDLR, promoting reverse cholesterol transport and facilitating the clearance of cholesterol from peripheral tissues. …”

Effects of Curcuma longa on the intestinal health of chicks infected with Salmonella Typhimurium by Gisele Mendanha Nascimento (6935009)

“…A randomized 4×2 factorial design scheme (C. longa levels × inoculation by Salmonella Typhimurium) was used. …”

Doxycycline-Dependent Smad7 Expression and TGF-β Signaling Inhibition in <i>Pdx1-tTA/Smad7</i> Adult Islets by Nora G Smart (72089)

“…<div><p>Data are from tissues of male mice aged 4–5 mo.</p> <p>(A–C and E–J) Smad7 expression by β cells in wild-type and <i>Pdx1-tTA</i> controls is undetectable while immunohistochemical studies demonstrate Smad7 expression (red) in insulin-expressing β cells (green) of bitransgenic <i>Pdx1-tTA, TRE-Smad7</i> adults. …”

Image_1_Characterization of Oxytocin Receptor Expression Within Various Neuronal Populations of the Mouse Dorsal Hippocampus.pdf by W. Scott Young (8591811)

“…Outside of those excitatory neurons, over 90% of Oxtr-expressing neurons co-express glutamic acid decarboxylase-1 (Gad-1) with progressively decreasing numbers of co-expressing cholecystokinin, somatostatin, parvalbumin, neuronal nitric oxide synthase, the serotonin 3a receptor, the vesicular glutamate transporter 3, calbindin 2 (calretinin), and vasoactive intestinal polypeptide neurons. …”